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GENE：MRPL57

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPL57
FullNmae mitochondrial ribosomal protein L57
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14514
EnsembleID ENSG00000173141
Uniprot Q9BQC6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPL57 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPL57 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPL57 GO:0003735,GO:0003735,GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005761,GO:0005761,GO:0005762,GO:0005762,GO:0032543,GO:0032543

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 MRPL57 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 MRPL57 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRPL57 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 MRPL57 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MRPL57 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MRPL57 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MRPL57 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000008A99 MRPL57 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000E7139 MRPL57 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000453664 MRPL57 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MRPL57 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MRPL28 MRPL57 25348397 N/A physical interaction ComPPI
KBTBD7 MRPL57 25348397 N/A physical interaction ComPPI
EWSR1 MRPL57 25348397 N/A physical interaction ComPPI
ABCC2 MRPL57 25348397 N/A physical interaction ComPPI
CREB3 MRPL57 25348397 N/A physical interaction ComPPI
PLP2 MRPL57 25348397 N/A physical interaction ComPPI
CIDEB MRPL57 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FBXW11 MRPL57 25348397 N/A physical interaction ComPPI
SLC25A10 MRPL57 25348397 N/A physical interaction ComPPI
HNRNPA1 MRPL57 25348397 N/A physical interaction ComPPI
MRPL4 MRPL57 25348397 N/A physical interaction ComPPI
MRPL12 MRPL57 25348397 N/A physical interaction ComPPI
MRPL19 MRPL57 25348397 N/A physical interaction ComPPI
EPB41 MRPL57 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
E2F3 MRPL57 22157815 24234451 25348397 association pull down ComPPI,IntAct
MRPL10 MRPL57 25348397 N/A physical interaction ComPPI
RPS8 MRPL57 25348397 N/A physical interaction ComPPI
MRPL1 MRPL57 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL15 MRPL57 25348397 N/A physical interaction ComPPI
MRPS30 MRPL57 25348397 N/A physical interaction ComPPI

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