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GENE：MRPS14

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS14
FullNmae mitochondrial ribosomal protein S14
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14049
EnsembleID ENSG00000120333
Uniprot O60783

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS14 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPS14 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS14 GO:0003723,GO:0003735,GO:0003735,GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005761,GO:0005763,GO:0005763,GO:0005763,GO:0006412,GO:0006412,GO:0031965,GO:0032543,GO:0032543

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRPS14 hsa:63931 path:hsa03010 Ribosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MRPS14 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MRPS14 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MRPS14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRPS14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MRPS14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MRPS14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MRPS14 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AD002 MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00006DE17B MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB0E MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032835F MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 MRPS14 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AAF6D MRPS14 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 MRPS14 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 MRPS14 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000019F055 MRPS14 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F MRPS14 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 MRPS14 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A MRPS14 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF MRPS14 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 MRPS14 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 MRPS14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 MRPS14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 MRPS14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 MRPS14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 MRPS14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 MRPS14 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TUFM MRPS14 25348397 N/A physical interaction ComPPI
SNRNP70 MRPS14 25348397 N/A physical interaction ComPPI
JUN MRPS14 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
YBX1 MRPS14 22118625 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HNRNPU MRPS14 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PINX1 MRPS14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MAP1LC3A MRPS14 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBGCP3 MRPS14 25348397 N/A physical interaction ComPPI
PDK1 MRPS14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPL6 MRPS14 25348397 N/A physical interaction ComPPI
RPL23 MRPS14 25348397 N/A physical interaction ComPPI
RBM42 MRPS14 25348397 N/A physical interaction ComPPI
AURKAIP1 MRPS14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRA2A MRPS14 25348397 N/A physical interaction ComPPI
IKBKE MRPS14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RAB5C MRPS14 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CEP250 MRPS14 25348397 N/A physical interaction ComPPI
TUBGCP4 MRPS14 25348397 N/A physical interaction ComPPI
DDX56 MRPS14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPD1 MRPS14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DLST MRPS14 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MRPS34 MRPS14 25348397 N/A physical interaction ComPPI
ILF3 MRPS14 25348397 N/A physical interaction ComPPI
SLC25A10 MRPS14 25348397 N/A physical interaction ComPPI
RPS2 MRPS14 25348397 N/A physical interaction ComPPI
RPS15A MRPS14 25348397 N/A physical interaction ComPPI
MRPL12 MRPS14 25348397 N/A physical interaction ComPPI
MRPS31 MRPS14 25348397 N/A physical interaction ComPPI
KSR1 MRPS14 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
FLOT2 MRPS14 25348397 N/A physical interaction ComPPI
TP53 MRPS14 25348397 N/A physical interaction ComPPI
ERBB3 MRPS14 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPS14 MRPS11 25348397 N/A physical interaction ComPPI
MRPS14 MRPS2 25348397 N/A physical interaction ComPPI
MRPS14 ZC3H3 25348397 N/A physical interaction ComPPI
MRPS14 RPS8 25348397 N/A physical interaction ComPPI
MRPS14 SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B MRPS14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MKI67 MRPS14 24234451 26949251 association anti tag coimmunoprecipitation IntAct

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