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GENE：MXD4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MXD4
FullNmae MAX dimerization protein 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13906
EnsembleID ENSG00000123933
Uniprot Q14582

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MXD4 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MXD4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MXD4 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0005515,GO:0005654,GO:0006357,GO:0046983

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MXD4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 MXD4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MXD4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MXD4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MXD4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MXD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MXD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MXD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MXD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MXD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MXD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR MXD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MXD4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000451A1 MXD4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SIN3A MXD4 14525934 25348397 8521822 N/A experimental interaction detection,in vivo ComPPI,HPRD
MXD1 MXD4 25348397 N/A physical interaction ComPPI
SMC3 MXD4 25348397 N/A physical interaction ComPPI
MLX MXD4 10593926 11230181 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MXD4 TCP10L 14525934 15469726 21988832 24234451 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct,OmniPath
MXD4 MAX 14525934 24234451 25348397 25609649 27705803 8521822 association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
SHBG MXD4 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MAX MXD4 10229200 10593926 25609649 27898060 7954804 8521822 9528857 inhibition,stimulant N/A OmniPath

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