Gene Information gene info

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GENE：MYT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYT1
FullNmae myelin transcription factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7622
EnsembleID ENSG00000196132
Uniprot Q01538

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYT1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYT1 GO:0000785,GO:0000981,GO:0003677,GO:0003700,GO:0005634,GO:0005654,GO:0005829,GO:0006355,GO:0006357,GO:0007399,GO:0008270,GO:0030154

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAPK8 MYT1 19204086 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
MAPK10 MYT1 19204086 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
PIN1 MYT1 10504341 23180781 9499405 physical association anti tag coimmunoprecipitation,pull down InnateDB
CDK1 MYT1 10504341 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF3 MYT1 22792062 23180781 physical association anti tag coimmunoprecipitation InnateDB
KDM5B MYT1 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
EZH2 MYT1 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MYT1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 MYT1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA1 MYT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MYT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MYT1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MYT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATM MYT1 12926986 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001B341F MYT1 N/A 18006846 rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS00001B341F MYT1 18006846 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 MYT1 25361965 interaction type N/A PTMCode2
MYT1 PIN1 25361965 interaction type N/A PTMCode2
PLK1 MYT1 25361965 interaction type N/A PTMCode2
MYT1 PLK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 MYT1 25348397 N/A physical interaction ComPPI
PLK1 MYT1 12738781 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TRAF3 MYT1 25348397 N/A physical interaction ComPPI
HNRNPL MYT1 25348397 N/A physical interaction ComPPI
AURKA MYT1 25348397 N/A physical interaction ComPPI
SIN3B MYT1 25348397 N/A physical interaction ComPPI
MYT1 HDAC1 25348397 N/A physical interaction ComPPI
MYT1 CDK1 14525934 24234451 25348397 9001210 9268380 phosphorylation reaction experimental interaction detection,in-gel kinase assay ComPPI,HPRD,IntAct
NPM1 MYT1 24234451 30021884 physical association cross-linking study IntAct
MAPK10 MYT1 19204086 27898060 N/A N/A OmniPath
MYT1 PIN1 10504341 27898060 9499405 N/A N/A OmniPath
PIN1 MYT1 10504341 27898060 9499405 N/A N/A OmniPath
MYT1 CDK1 10504341 18452278 18669648 18691976 19413330 19415658 19651622 19901323 20068230 20068231 27898060 9001210 9268380 inhibition N/A OmniPath
MAPK8 MYT1 19204086 27898060 N/A N/A OmniPath
MYT1 MAPK8 19204086 27898060 N/A N/A OmniPath
TRAF3 MYT1 22792062 27898060 N/A N/A OmniPath

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