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GENE：NDEL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDEL1
FullNmae nudE neurodevelopment protein 1 like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17620
EnsembleID ENSG00000166579
Uniprot Q9GZM8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDEL1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NDEL1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NDEL1 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
NDEL1 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
NDEL1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NDEL1 GO:0000132,GO:0000776,GO:0000776,GO:0001833,GO:0005515,GO:0005813,GO:0005819,GO:0005829,GO:0005871,GO:0005874,GO:0007020,GO:0007059,GO:0007059,GO:0007100,GO:0008017,GO:0008021,GO:0008090,GO:0008286,GO:0010975,GO:0016477,GO:0021799,GO:0021955,GO:0031252,GO:0032418,GO:0033157,GO:0042802,GO:0043014,GO:0043203,GO:0043547,GO:0047496,GO:0048487,GO:0051303,GO:0051642,GO:0060052,GO:0060053,GO:0140650,GO:1900029,GO:1904115,GO:1990138

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR NDEL1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NDEL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NDEL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NDEL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 NDEL1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NDEL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NDEL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NDEL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NDEL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB NDEL1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 NDEL1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000065D58 NDEL1 18668040 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS00001F0C23 NDEL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007A060 NDEL1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A NDEL1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 NDEL1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A NDEL1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 NDEL1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 NDEL1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 NDEL1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 NDEL1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F NDEL1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 NDEL1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 NDEL1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB0E NDEL1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 NDEL1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 NDEL1 22135298 phosphorylation N/A PhosphoSite
MAPK1 NDEL1 22135298 phosphorylation N/A PhosphoSite
YWHAE NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 YWHAE 25361965 interaction type N/A PTMCode2
LMNB1 NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 LMNB1 25361965 interaction type N/A PTMCode2
BUB1 NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 BUB1 25361965 interaction type N/A PTMCode2
NDEL1 DYNC1H1 25361965 interaction type N/A PTMCode2
DYNC1H1 NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 PCNT 25361965 interaction type N/A PTMCode2
PCNT NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 DIXDC1 25361965 interaction type N/A PTMCode2
DIXDC1 NDEL1 25361965 interaction type N/A PTMCode2
CDK5 NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 CDK5 25361965 interaction type N/A PTMCode2
CDC42 NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 CDC42 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF572 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GOLGA2 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BCAS2 NDEL1 25348397 N/A physical interaction ComPPI
AIMP2 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF230 NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZNF490 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDC42 NDEL1 25348397 N/A anti tag coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
NDC80 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MIS18A NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNAP29 NDEL1 25348397 N/A physical interaction ComPPI
ZNF264 NDEL1 25348397 N/A physical interaction ComPPI
ZNF707 NDEL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZNF180 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YWHAG NDEL1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BMI1 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRT40 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF844 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF544 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BORCS6 NDEL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TACC3 NDEL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PICK1 NDEL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KTN1 NDEL1 25348397 N/A physical interaction ComPPI
KALRN NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TUBG1 NDEL1 25348397 N/A physical interaction ComPPI
PKP2 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNX6 NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BUB1 NDEL1 17600710 24234451 25348397 colocalization fluorescence technology ComPPI,IntAct
PXN NDEL1 19492042 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
RPS6KA3 NDEL1 25348397 N/A physical interaction ComPPI
NDE1 NDEL1 22843697 24234451 25348397 physical association cross-linking study,physical interaction ComPPI,IntAct
VCL NDEL1 19492042 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CEP135 NDEL1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CTR9 NDEL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UTRN NDEL1 25348397 N/A physical interaction ComPPI
XPA NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PAFAH1B1 NDEL1 10931877 11163260 14525934 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
CCDC183 NDEL1 25348397 N/A physical interaction ComPPI
ABI3 NDEL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MED11 NDEL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TUBA1A NDEL1 25348397 N/A physical interaction ComPPI
YWHAE NDEL1 12796778 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
LMNB1 NDEL1 25348397 N/A physical interaction ComPPI
EVI5 NDEL1 25348397 N/A physical interaction ComPPI
SNTA1 NDEL1 25348397 N/A physical interaction ComPPI
SSX2IP NDEL1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ZNF197 NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK5 NDEL1 12796778 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ZNF10 NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNTB1 NDEL1 25348397 N/A physical interaction ComPPI
SNTB2 NDEL1 25348397 N/A physical interaction ComPPI
DTNB NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SYNE1 NDEL1 25348397 N/A physical interaction ComPPI
GRIPAP1 NDEL1 25348397 N/A physical interaction ComPPI
DYNC1H1 NDEL1 11163259 11163260 14525934 14970193 15208636 18331715 18784752 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
MLLT10 NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CENPF NDEL1 17043677 17600710 24234451 25348397 colocalization,physical association two hybrid,fluorescence technology,pull down,physical interaction ComPPI,IntAct
IMMT NDEL1 25348397 N/A two hybrid,far western blotting,pull down,physical interaction,physical interaction ComPPI
MBIP NDEL1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BRK1 NDEL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLT1 NDEL1 25348397 N/A physical interaction ComPPI
NUP54 NDEL1 25348397 N/A physical interaction ComPPI
KIF20B NDEL1 25348397 N/A physical interaction ComPPI
CLPX NDEL1 25348397 N/A physical interaction ComPPI
TRIM27 NDEL1 24234451 25348397 25416956 physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PAFAH1B2 NDEL1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NDEL1 MAGEA11 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NDEL1 DISC1 12506198 12812986 14525934 17043677 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,far western blotting,physical interaction,fluorescence microscopy,two hybrid ComPPI,HPRD,IntAct
NDEL1 CCDC88A 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 CEP170 25348397 N/A physical interaction ComPPI
NDEL1 CEP63 25348397 N/A physical interaction ComPPI
NDEL1 ANK2 25348397 N/A physical interaction ComPPI
NDEL1 CCSER1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 LUC7L2 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 CCSER2 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 DIXDC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 MRC2 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 ZNF17 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 ZNF211 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 ZNF91 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDEL1 DCTN2 25348397 N/A physical interaction ComPPI
NDEL1 KATNA1 25348397 N/A physical interaction ComPPI
NDEL1 KATNB1 25348397 N/A physical interaction ComPPI
NDEL1 APP 25348397 N/A physical interaction ComPPI
NDEL1 KIFC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 USP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 SNAPC5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 CCHCR1 25348397 N/A physical interaction ComPPI
NDEL1 TRAF3IP3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 CWF19L2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 ZNF417 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 ZNF599 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 SCARA3 25348397 N/A physical interaction ComPPI
NDEL1 NAP1L5 25348397 N/A physical interaction ComPPI
NDEL1 DYNC1I1 19927128 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NDEL1 CEP152 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NDEL1 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NDEL1 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NDEL1 ANKRD26 25348397 N/A physical interaction ComPPI
NDEL1 FBXW5 25348397 N/A physical interaction ComPPI
NDEL1 ZNF445 25348397 N/A physical interaction ComPPI
NDEL1 MTCL1 25348397 N/A physical interaction ComPPI
NDEL1 CCDC18 25348397 N/A physical interaction ComPPI
NDEL1 SLC25A43 25348397 N/A physical interaction ComPPI
NDEL1 SHTN1 25348397 N/A physical interaction ComPPI
NDEL1 OFD1 25348397 N/A physical interaction ComPPI
NDEL1 TRIM7 25348397 N/A physical interaction ComPPI
NDEL1 TRIOBP 25348397 N/A physical interaction ComPPI
NDEL1 PRPF19 25348397 N/A physical interaction ComPPI
NDEL1 PTPN14 25348397 N/A physical interaction ComPPI
NDEL1 LNX1 25348397 N/A physical interaction ComPPI
NDEL1 ZNF365 16682949 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
NDEL1 CDK1 16682949 24234451 25348397 phosphorylation reaction in-gel kinase assay ComPPI,IntAct
NDEL1 TCTE1 24234451 25348397 26638075 association proximity-dependent biotin identification ComPPI,IntAct
NDEL1 MLLT6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDEL1 ZNF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDEL1 PARVG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDEL1 ZNF12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDEL1 ZNF35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZNF260 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDEL1 NDEL1 10931877 17997972 22843697 24234451 25416956 physical association two hybrid,cross-linking study,light scattering,molecular sieving,x-ray crystallography,two hybrid array,comigration in sds page,two hybrid prey pooling approach IntAct
CDK5 NDEL1 11163260 12796778 18669648 19413330 20068231 27898060 stimulant N/A OmniPath
AURKA NDEL1 17060449 27898060 stimulant N/A OmniPath
CDK1 NDEL1 12556484 16682949 17060449 18669648 27898060 stimulant N/A OmniPath
MAPK1 NDEL1 18669648 27898060 N/A N/A OmniPath
YWHAE NDEL1 12796778 16944949 17202468 18331715 27898060 stimulant N/A OmniPath
PPP4C NDEL1 18347064 27898060 inhibition N/A OmniPath
DISC1 NDEL1 12506198 12812986 14962739 17043677 17202468 20880836 27898060 stimulant N/A OmniPath
ZDHHC2 NDEL1 19927128 27898060 N/A N/A OmniPath

Visualization










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