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GENE：NFRKB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NFRKB
FullNmae nuclear factor related to kappaB binding protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7802
EnsembleID ENSG00000170322
Uniprot Q6P4R8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NFRKB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NFRKB GO:0000723,GO:0002020,GO:0002020,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006275,GO:0006281,GO:0006282,GO:0006310,GO:0006338,GO:0031011,GO:0033044,GO:0045739,GO:0045893,GO:0045995,GO:0051726,GO:0060382,GO:1904507

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NFRKB hsa:4798 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NFRKB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NFRKB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 NFRKB 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 NFRKB 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 NFRKB 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 NFRKB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF NFRKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NFRKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NFRKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005C1F22 NFRKB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018D2BE NFRKB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 NFRKB 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TFPT NFRKB 25348397 N/A physical interaction ComPPI
PSMC3 NFRKB 25348397 N/A physical interaction ComPPI
HSP90AB1 NFRKB 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
INO80B NFRKB 16230350 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNDBP1 NFRKB 25348397 N/A physical interaction ComPPI
HSP90AA1 NFRKB 25348397 N/A physical interaction ComPPI
RUVBL1 NFRKB 25348397 N/A physical interaction ComPPI
EWSR1 NFRKB 25348397 N/A physical interaction ComPPI
CUL2 NFRKB 25348397 N/A physical interaction ComPPI
IPO7 NFRKB 25348397 N/A physical interaction ComPPI
CAV3 NFRKB 25348397 N/A physical interaction ComPPI
YY1 NFRKB 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
MCRS1 NFRKB 16230350 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTL6A NFRKB 16230350 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPS1 NFRKB 25348397 N/A physical interaction ComPPI
CDC37 NFRKB 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NFKB1 NFRKB 14525934 2050119 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
EPHB3 NFRKB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ACTR8 NFRKB 16230350 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLT1 NFRKB 25348397 N/A physical interaction ComPPI
TERF2 NFRKB 25348397 N/A physical interaction ComPPI
CARD8 NFRKB 25348397 N/A physical interaction ComPPI
CARD9 NFRKB 25348397 N/A physical interaction ComPPI
IL20RA NFRKB 25348397 N/A physical interaction ComPPI
RUVBL2 NFRKB 25348397 N/A physical interaction ComPPI
UCHL5 NFRKB 17721549 18922472 19615732 24234451 25194926 25348397 25416956 25702870 25702872 26186194 27898060 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
ADRM1 NFRKB 18922472 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EMILIN1 NFRKB 25348397 N/A physical interaction ComPPI
KPTN NFRKB 25348397 N/A physical interaction ComPPI
NFRKB INO80 25348397 N/A physical interaction ComPPI
NFRKB INO80E 16230350 18922472 21303910 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NFRKB DLK1 25348397 N/A physical interaction ComPPI
NFRKB BCL7C 25348397 N/A physical interaction ComPPI
NFRKB CCDC102B 25348397 N/A physical interaction ComPPI

Visualization










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