Gene Information gene info

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GENE：NUP50

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUP50
FullNmae nucleoporin 50
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8065
EnsembleID ENSG00000093000
Uniprot Q9UKX7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUP50 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NUP50 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NUP50 GO:0005515,GO:0005635,GO:0005643,GO:0005654,GO:0005654,GO:0006606,GO:0006913,GO:0031965,GO:0051028

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NUP50 hsa:10762 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)
NUP50 hsa:10762 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR NUP50 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA NUP50 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000070B1D NUP50 20371350 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00003D5391 NUP50 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008F0CF NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 NUP50 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C NUP50 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D NUP50 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 NUP50 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A NUP50 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000034B6F5 NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 NUP50 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075ADAC NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D NUP50 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 NUP50 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC379 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C NUP50 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 NUP50 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 NUP50 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF NUP50 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 NUP50 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000028BB8 NUP50 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 NUP50 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 NUP50 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041E11D NUP50 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000072E4C NUP50 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 NUP50 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK3 NUP50 22135298 phosphorylation N/A PhosphoSite
CDK1 NUP50 22135298 phosphorylation N/A PhosphoSite
MAPK1 NUP50 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
KPNA2 NUP50 12176322 14525934 24234451 25348397 25416956 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
KPNA3 NUP50 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KPNA4 NUP50 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KPNA5 NUP50 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IPO13 NUP50 25348397 N/A physical interaction ComPPI
PPP1CC NUP50 24234451 24366813 25348397 28330616 association anti tag coimmunoprecipitation,pull down,proximity-dependent biotin identification ComPPI,IntAct
LDHB NUP50 25348397 N/A physical interaction ComPPI
NPM1 NUP50 25348397 N/A physical interaction ComPPI
HSPBP1 NUP50 25348397 N/A physical interaction ComPPI
IMPDH2 NUP50 25348397 N/A physical interaction ComPPI
KIF5B NUP50 25348397 N/A physical interaction ComPPI
CDKN1B NUP50 10811608 10891500 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
TP53BP1 NUP50 25348397 N/A physical interaction ComPPI
KPNA1 NUP50 24234451 25348397 25416956 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LMNA NUP50 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MRGBP NUP50 25348397 N/A physical interaction ComPPI
RAN NUP50 12176322 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CCDC22 NUP50 25348397 N/A physical interaction ComPPI
KEAP1 NUP50 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PFDN4 NUP50 25348397 N/A physical interaction ComPPI
SMARCD1 NUP50 25348397 N/A physical interaction ComPPI
EIF4G1 NUP50 25348397 N/A physical interaction ComPPI
CUL3 NUP50 25348397 N/A physical interaction ComPPI
KPNB1 NUP50 12176322 14525934 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
NUP85 NUP50 25348397 N/A physical interaction ComPPI
PRKAA1 NUP50 25348397 N/A physical interaction ComPPI
PPP1R3A NUP50 25348397 N/A physical interaction ComPPI
NTRK1 NUP50 25348397 N/A physical interaction ComPPI
PTPN2 NUP50 25348397 N/A physical interaction ComPPI
PLEC NUP50 25348397 N/A physical interaction ComPPI
GMFB NUP50 25348397 N/A physical interaction ComPPI
DUSP4 NUP50 25348397 N/A physical interaction ComPPI
STXBP1 NUP50 25348397 N/A physical interaction ComPPI
RANBP1 NUP50 25348397 N/A physical interaction ComPPI
XPO1 NUP50 10891499 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
AP2B1 NUP50 25348397 N/A physical interaction ComPPI
EPB41L1 NUP50 25348397 N/A physical interaction ComPPI
TAF4 NUP50 25348397 N/A physical interaction ComPPI
HDAC6 NUP50 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NARS1 NUP50 25348397 N/A physical interaction ComPPI
FLNB NUP50 25348397 N/A physical interaction ComPPI
NUP153 NUP50 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RANBP2 NUP50 25348397 N/A physical interaction ComPPI
NISCH NUP50 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SART3 NUP50 25348397 N/A physical interaction ComPPI
BRD7 NUP50 25348397 N/A physical interaction ComPPI
GARS1 NUP50 25348397 N/A physical interaction ComPPI
PSME3 NUP50 25348397 N/A physical interaction ComPPI
ELP1 NUP50 25348397 N/A physical interaction ComPPI
NUP50 SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP50 APP 25348397 N/A physical interaction ComPPI
NUP50 UBAP2 25348397 N/A physical interaction ComPPI
NUP50 TOR1AIP1 25348397 N/A physical interaction ComPPI
NUP50 SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
NUP50 ACACA 25348397 N/A physical interaction ComPPI
NUP50 WASHC4 25348397 N/A physical interaction ComPPI
NUP50 TSC22D1 25348397 N/A physical interaction ComPPI
NUP50 TTI1 25348397 N/A physical interaction ComPPI
NUP50 PHF10 25348397 N/A physical interaction ComPPI
NUP50 WDHD1 25348397 N/A physical interaction ComPPI
NUP50 SMARCC2 25348397 N/A physical interaction ComPPI
NUP50 BOD1L1 25348397 N/A physical interaction ComPPI
NUP50 ARID2 25348397 N/A physical interaction ComPPI
NUP50 KIFC1 25348397 N/A physical interaction ComPPI
NUP50 PBRM1 25348397 N/A physical interaction ComPPI
NUP50 SMARCD3 25348397 N/A physical interaction ComPPI
NUP50 SMARCD2 25348397 N/A physical interaction ComPPI
NUP50 KLHL7 25348397 N/A physical interaction ComPPI
NUP50 FBXO28 25348397 N/A physical interaction ComPPI
NUP50 BCL7B 25348397 N/A physical interaction ComPPI
NUP50 RNGTT 25348397 N/A physical interaction ComPPI
NUP50 SETD1A 25348397 N/A physical interaction ComPPI
NUP50 CDCA2 25348397 N/A physical interaction ComPPI
NUP50 SPOP 25348397 N/A physical interaction ComPPI
NUP50 CXXC1 25348397 N/A physical interaction ComPPI
NUP50 KIF18B 25348397 N/A physical interaction ComPPI
NUP50 FBXW11 25348397 N/A physical interaction ComPPI
NUP50 ASNS 25348397 N/A physical interaction ComPPI
NUP50 CDV3 25348397 N/A physical interaction ComPPI
NUP50 KHSRP 25348397 N/A physical interaction ComPPI
NUP50 PFDN2 25348397 N/A physical interaction ComPPI
NUP50 PAIP1 25348397 N/A physical interaction ComPPI
NUP50 SBDS 25348397 N/A physical interaction ComPPI
NUP50 IFI16 25348397 N/A physical interaction ComPPI
NUP50 NUP43 25348397 N/A physical interaction ComPPI
NUP50 NUP107 25348397 N/A physical interaction ComPPI
NUP50 NUP133 25348397 N/A physical interaction ComPPI
NUP50 NUP160 25348397 N/A physical interaction ComPPI
NUP50 NUP35 25348397 N/A physical interaction ComPPI
NUP50 B9D2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NUP50 DYNLT1 25348397 N/A physical interaction ComPPI
NUP50 MARF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NUP50 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NUP50 PAN2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NUP50 EIF4ENIF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NUP50 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NUP50 LRRK2 23075850 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUP50 TCTE1 24234451 25348397 26638075 association proximity-dependent biotin identification ComPPI,IntAct
NUP50 SOWAHA 24234451 25348397 physical association inference by socio-affinity scoring ComPPI,IntAct
KPNA6 NUP50 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CSW NUP50 25348397 N/A physical interaction ComPPI
NUP50 RAS85D 25348397 N/A anti tag coimmunoprecipitation ComPPI
NUP50 TAK1 25348397 N/A physical interaction ComPPI
NUP50 RAF 25348397 N/A physical interaction ComPPI
NUP50 MYC 25348397 N/A physical interaction ComPPI
NUP50 PDK1 25348397 N/A physical interaction ComPPI
NUP50 DOS 25348397 N/A physical interaction ComPPI
H1-2 NUP50 24234451 30021884 physical association cross-linking study IntAct
H3-4 NUP50 24234451 30021884 physical association cross-linking study IntAct
H2BC5 NUP50 24234451 30021884 physical association cross-linking study IntAct
H2BC21 NUP50 24234451 30021884 physical association cross-linking study IntAct
H2BC13 NUP50 24234451 30021884 physical association cross-linking study IntAct
H2BC9 NUP50 24234451 30021884 physical association cross-linking study IntAct
HDAC1 NUP50 24234451 30021884 physical association cross-linking study IntAct
MAPK3 NUP50 19767751 27898060 inhibition N/A OmniPath
CDK1 NUP50 19767751 27898060 inhibition N/A OmniPath
MAPK1 NUP50 19767751 27898060 inhibition,stimulant N/A OmniPath

Visualization










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