Gene Information gene info

GENE:PELO

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PELO
FullNmae pelota mRNA surveillance and ribosome rescue factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8829
EnsembleID ENSG00000152684
Uniprot Q9BRX2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PELO autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PELO GO:0001833,GO:0005515,GO:0005737,GO:0006417,GO:0007049,GO:0007492,GO:0019827,GO:0022626,GO:0030513,GO:0032790,GO:0032790,GO:0043022,GO:0046872,GO:0051276,GO:0051301,GO:0060231,GO:0070481,GO:0070651,GO:0070966,GO:0070966,GO:0071025,GO:0072344,GO:0170011,GO:1990533

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PELO hsa:53918 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PELO 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PELO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PELO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PELO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PELO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PELO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 PELO 17669516 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 PELO 17669516 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 PELO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 PELO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075A513 PELO 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B PELO 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B PELO 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 PELO 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC PELO 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B PELO 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LMO4 PELO 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF3G PELO 20406461 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,bimolecular fluorescence complementation ComPPI,IntAct
CDC5L PELO 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 PELO 25348397 N/A physical interaction ComPPI
KEAP1 PELO 25348397 N/A physical interaction ComPPI
PELO RUVBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO AIFM1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO ABCD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO HEATR1 25348397 N/A physical interaction ComPPI
PELO HACD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO TIMM50 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO FANCI 25348397 N/A physical interaction ComPPI
PELO SLC25A12 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO MCM7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO MYC 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PELO CUL3 25348397 N/A physical interaction ComPPI
PELO ECT2 25348397 N/A physical interaction ComPPI
PELO MDC1 25348397 N/A physical interaction ComPPI
PELO PAXIP1 25348397 N/A physical interaction ComPPI
PELO HDAC6 25348397 N/A physical interaction ComPPI
PELO PRMT6 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PELO HBS1L 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PELO EGFR 25348397 N/A physical interaction ComPPI
PELO HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
PELO NOP56 25348397 N/A physical interaction ComPPI
PELO SMARCA4 25348397 N/A physical interaction ComPPI
PELO YBX3 25348397 N/A physical interaction ComPPI
PELO PIK3R3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
PELO PTEN 25348397 N/A physical interaction ComPPI
PELO XPO1 25348397 N/A physical interaction ComPPI
PELO G3BP1 25348397 N/A physical interaction ComPPI
PELO PSMD4 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PELO RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PELO JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PELO DYNLT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PELO HAX1 20406461 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,fluorescence microscopy,bimolecular fluorescence complementation ComPPI,IntAct
PELO CHICO 14605208 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct

Visualization