GENE:PLEKHB2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PLEKHB2 |
| FullNmae | pleckstrin homology domain containing B2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:19236 |
| EnsembleID | ENSG00000115762 |
| Uniprot | Q96CS7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PLEKHB2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PLEKHB2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PLEKHB2 | GO:0005515,GO:0005547,GO:0045595,GO:0055038 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PLEKHB2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | PLEKHB2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| PRDM14 | PLEKHB2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | PLEKHB2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000070B1D | PLEKHB2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000039A052 | PLEKHB2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003D5391 | PLEKHB2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000005481D | PLEKHB2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002367FA | PLEKHB2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000016D2D4 | PLEKHB2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000001EB3 | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000345DEB | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058BB84 | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D1FC | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000008A99 | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | PLEKHB2 | 22012620 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000544FF1 | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEE35 | PLEKHB2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000E601 | PLEKHB2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007FBA | PLEKHB2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | PLEKHB2 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | PLEKHB2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | PLEKHB2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | PLEKHB2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000007A060 | PLEKHB2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | PLEKHB2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | PLEKHB2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | PLEKHB2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SNRPB | PLEKHB2 | 25348397 | N/A | two hybrid | ComPPI |
| RHOXF2 | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| BHLHE40 | PLEKHB2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| UBASH3A | PLEKHB2 | 25348397 | N/A | two hybrid | ComPPI |
| PSMD14 | PLEKHB2 | 16169070 24234451 25348397 | physical association | two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| DCUN1D1 | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| KRT31 | PLEKHB2 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HEYL | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBB | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBC | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RPS27A | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBA52 | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| HEY1 | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| STAM2 | PLEKHB2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| UBAC1 | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBQLN2 | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| EPN1 | PLEKHB2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| POGZ | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ITCH | PLEKHB2 | 25348397 | N/A | physical interaction | ComPPI |
| TAX1BP1 | PLEKHB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UPF1 | PLEKHB2 | 15231747 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TRIM25 | PLEKHB2 | 25348397 | N/A | physical interaction | ComPPI |
| PLEKHB2 | KRT85 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PLEKHB2 | KRT82 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PLEKHB2 | C1ORF94 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| PLEKHB2 | MAP3K1 | 25348397 | N/A | physical interaction | ComPPI |
| PLEKHB2 | ATF7IP | 15231748 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| PLEKHB2 | GJB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLEKHB2 | CD68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLEKHB2 | UBXN6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLEKHB2 | NTAQ1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLEKHB2 | OTUB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLEKHB2 | GLIS2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| BIRC2 | PLEKHB2 | 24234451 30561431 | association | virotrap | IntAct |
| TANK | PLEKHB2 | 24234451 30561431 | association | virotrap | IntAct |
| TNIP1 | PLEKHB2 | 24234451 30561431 | association | virotrap | IntAct |
| TNFAIP3 | PLEKHB2 | 24234451 30561431 | association | virotrap | IntAct |
| TRAF2 | PLEKHB2 | 24234451 30561431 | association | virotrap | IntAct |
| IKBKG | PLEKHB2 | 24234451 30561431 | association | virotrap | IntAct |
