Gene Information gene info

GENE:PLEKHB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLEKHB2
FullNmae pleckstrin homology domain containing B2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19236
EnsembleID ENSG00000115762
Uniprot Q96CS7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLEKHB2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PLEKHB2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLEKHB2 GO:0005515,GO:0005547,GO:0045595,GO:0055038

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PLEKHB2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PLEKHB2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 PLEKHB2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PLEKHB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D PLEKHB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039A052 PLEKHB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 PLEKHB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PLEKHB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA PLEKHB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 PLEKHB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000001EB3 PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 PLEKHB2 22012620 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000544FF1 PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 PLEKHB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 PLEKHB2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA PLEKHB2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 PLEKHB2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PLEKHB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041CB9C PLEKHB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000040EE1D PLEKHB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000007A060 PLEKHB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000F0F49 PLEKHB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000007D64A PLEKHB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E1509 PLEKHB2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNRPB PLEKHB2 25348397 N/A two hybrid ComPPI
RHOXF2 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 PLEKHB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBASH3A PLEKHB2 25348397 N/A two hybrid ComPPI
PSMD14 PLEKHB2 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
DCUN1D1 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT31 PLEKHB2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HEYL PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBB PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBC PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPS27A PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBA52 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEY1 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STAM2 PLEKHB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBAC1 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBQLN2 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EPN1 PLEKHB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
POGZ PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ITCH PLEKHB2 25348397 N/A physical interaction ComPPI
TAX1BP1 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UPF1 PLEKHB2 15231747 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRIM25 PLEKHB2 25348397 N/A physical interaction ComPPI
PLEKHB2 KRT85 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PLEKHB2 KRT82 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PLEKHB2 C1ORF94 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PLEKHB2 MAP3K1 25348397 N/A physical interaction ComPPI
PLEKHB2 ATF7IP 15231748 24234451 25348397 physical association two hybrid ComPPI,IntAct
PLEKHB2 GJB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLEKHB2 CD68 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLEKHB2 UBXN6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLEKHB2 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLEKHB2 OTUB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLEKHB2 GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BIRC2 PLEKHB2 24234451 30561431 association virotrap IntAct
TANK PLEKHB2 24234451 30561431 association virotrap IntAct
TNIP1 PLEKHB2 24234451 30561431 association virotrap IntAct
TNFAIP3 PLEKHB2 24234451 30561431 association virotrap IntAct
TRAF2 PLEKHB2 24234451 30561431 association virotrap IntAct
IKBKG PLEKHB2 24234451 30561431 association virotrap IntAct

Visualization