Gene Information gene info

  1. Home

GENE：BRAF

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BRAF
FullNmae B-Raf proto-oncogene, serine/threonine kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1097
EnsembleID ENSG00000157764
Uniprot P15056

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BRAF necroptosis 26355347 Our data suggest that loss of RIPK3 in melanoma and selective inhibition of the RIPK3/MLKL axis by BRAF inhibitor Dabrafenib, but not Vemurafenib, is critical to protect from necroptosis. retulator signature
BRAF autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BRAF GO:0000165,GO:0000165,GO:0002318,GO:0004672,GO:0004674,GO:0004708,GO:0004709,GO:0005509,GO:0005515,GO:0005524,GO:0005634,GO:0005739,GO:0005829,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0006468,GO:0007173,GO:0008542,GO:0009887,GO:0010628,GO:0010764,GO:0010828,GO:0016079,GO:0030878,GO:0031434,GO:0033077,GO:0033138,GO:0034446,GO:0035019,GO:0042802,GO:0043005,GO:0043066,GO:0043149,GO:0043231,GO:0043367,GO:0043369,GO:0043434,GO:0043524,GO:0044297,GO:0044877,GO:0045580,GO:0048538,GO:0048680,GO:0050772,GO:0050852,GO:0051496,GO:0051591,GO:0060291,GO:0060323,GO:0060324,GO:0070371,GO:0070374,GO:0070413,GO:0071277,GO:0071466,GO:0072577,GO:0090150,GO:0097110,GO:0098793,GO:0106310,GO:1900026,GO:1990090,GO:2000301,GO:2000352

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BRAF hsa:673 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
BRAF hsa:673 path:hsa01522 Endocrine resistance - Homo sapiens (human)
BRAF hsa:673 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
BRAF hsa:673 path:hsa04510 Focal adhesion - Homo sapiens (human)
BRAF hsa:673 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
BRAF hsa:673 path:hsa04720 Long-term potentiation - Homo sapiens (human)
BRAF hsa:673 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04726 Serotonergic synapse - Homo sapiens (human)
BRAF hsa:673 path:hsa04730 Long-term depression - Homo sapiens (human)
BRAF hsa:673 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
BRAF hsa:673 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
BRAF hsa:673 path:hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human)
BRAF hsa:673 path:hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)
BRAF hsa:673 path:hsa04934 Cushing syndrome - Homo sapiens (human)
BRAF hsa:673 path:hsa05010 Alzheimer disease - Homo sapiens (human)
BRAF hsa:673 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
BRAF hsa:673 path:hsa05034 Alcoholism - Homo sapiens (human)
BRAF hsa:673 path:hsa05160 Hepatitis C - Homo sapiens (human)
BRAF hsa:673 path:hsa05161 Hepatitis B - Homo sapiens (human)
BRAF hsa:673 path:hsa05200 Pathways in cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
BRAF hsa:673 path:hsa05210 Colorectal cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)
BRAF hsa:673 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05213 Endometrial cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05214 Glioma - Homo sapiens (human)
BRAF hsa:673 path:hsa05215 Prostate cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05216 Thyroid cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05218 Melanoma - Homo sapiens (human)
BRAF hsa:673 path:hsa05219 Bladder cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
BRAF hsa:673 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)
BRAF hsa:673 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05224 Breast cancer - Homo sapiens (human)
BRAF hsa:673 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
BRAF hsa:673 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GRB2 BRAF 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26192618 26552706 7510700 8551221 9510155 interaction type N/A ACSN
KSR1 BRAF 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 18332145 19449109 19541618 19565474 19568798 19615955 21102635 22435554 23180781 24027568 26192618 26552706 7510700 8551221 9510155 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
HRAS BRAF 10545207 16803888 18098337 18988627 23180781 23331499 7706312 9154803 stimulation,physical association anti tag coimmunoprecipitation,two hybrid InnateDB,SignaLink,SignaLink
RAF1 BRAF 16803888 23180781 physical association anti tag coimmunoprecipitation InnateDB
RB1 BRAF 15485920 23180781 physical association gst pull down InnateDB
MAP2K1 BRAF 15485920 23180781 physical association gst pull down InnateDB
BRAF RHEB 12214276 15150271 23180781 physical association anti tag coimmunoprecipitation InnateDB
BRAF MAP2K1 16810323 16888650 18988627 21071413 23331499 7731720 7835430 8157000 8394352 8621729 stimulation N/A SignaLink,SignaLink
BRAF MAP2K2 23331499 8668348 stimulation N/A SignaLink,SignaLink
PEBP1 BRAF 10490027 23331499 stimulation N/A SignaLink,SignaLink
KRAS BRAF 17635919 23331499 stimulation N/A SignaLink,SignaLink
RAP1B BRAF 12446733 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
YWHAB BRAF 10931830 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
YWHAG BRAF 20005715 interaction type N/A PSP
YWHAH BRAF 20005715 interaction type N/A PSP
YWHAQ BRAF 20005715 interaction type N/A PSP
YWHAZ BRAF 20005715 interaction type N/A PSP
YWHAQ BRAF 20005715 20005715 N/A N/A SignaLink
YWHAZ BRAF 18988627 20005715 20005715 8668348 N/A N/A SignaLink
YWHAG BRAF 15324660 18988627 20005715 20005715 N/A N/A SignaLink
YWHAH BRAF 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 BRAF 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 BRAF 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 BRAF 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 BRAF 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 BRAF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 BRAF N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE BRAF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 BRAF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002B2B5C BRAF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000008A99 BRAF 23128394 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004F4657 BRAF 23128394 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001B0D1E BRAF 25416803 27503895 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 BRAF 22135298 phosphorylation N/A PhosphoSite
MAPK3 BRAF 22135298 phosphorylation N/A PhosphoSite
MAPK1 BRAF 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PAK1 BRAF 22135298 phosphorylation N/A PhosphoSite
BRAF SLC9A1 22135298 phosphorylation N/A PhosphoSite
BRAF BAD 22135298 phosphorylation N/A PhosphoSite
BRAF EEF1A1 22135298 phosphorylation N/A PhosphoSite
BRAF BRAF 22135298 phosphorylation N/A PhosphoSite
BRAF MAP2K1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
BRAF EEF1A2 22135298 phosphorylation N/A PhosphoSite
BRAF TTK 22135298 phosphorylation N/A PhosphoSite
BRAF MAP2K2 22135298 phosphorylation N/A PhosphoSite
AKT3 BRAF 22135298 phosphorylation N/A PhosphoSite
AKT1 BRAF 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RHEB BRAF 25361965 interaction type N/A PTMCode2
BRAF RHEB 25361965 interaction type N/A PTMCode2
RAF1 BRAF 25361965 interaction type N/A PTMCode2
BRAF RAF1 25361965 interaction type N/A PTMCode2
BRAF MAPK1 25361965 interaction type N/A PTMCode2
HSPA8 BRAF 25361965 interaction type N/A PTMCode2
BRAF HSPA8 25361965 interaction type N/A PTMCode2
YWHAE BRAF 25361965 interaction type N/A PTMCode2
BRAF YWHAE 25361965 interaction type N/A PTMCode2
BRAF HSPA9 25361965 interaction type N/A PTMCode2
HSPA9 BRAF 25361965 interaction type N/A PTMCode2
BRAF YWHAB 25361965 interaction type N/A PTMCode2
YWHAB BRAF 25361965 interaction type N/A PTMCode2
MAP2K1 BRAF 25361965 interaction type N/A PTMCode2
BRAF PRKCE 25361965 interaction type N/A PTMCode2
PRKCE BRAF 25361965 interaction type N/A PTMCode2
BRAF YWHAG 25361965 interaction type N/A PTMCode2
YWHAG BRAF 25361965 interaction type N/A PTMCode2
BRAF HRAS 25361965 interaction type N/A PTMCode2
HRAS BRAF 25361965 interaction type N/A PTMCode2
BRAF PHKB 25361965 interaction type N/A PTMCode2
PHKB BRAF 25361965 interaction type N/A PTMCode2
BRAF RAP1A 25361965 interaction type N/A PTMCode2
RAP1A BRAF 25361965 interaction type N/A PTMCode2
BRAF RAP1GAP 25361965 interaction type N/A PTMCode2
RAP1GAP BRAF 25361965 interaction type N/A PTMCode2
BRAF HSPA1A 25361965 interaction type N/A PTMCode2
HSPA1A BRAF 25361965 interaction type N/A PTMCode2
BRAF ARAF 25361965 interaction type N/A PTMCode2
ARAF BRAF 25361965 interaction type N/A PTMCode2
BRAF MAP3K1 25361965 interaction type N/A PTMCode2
MAP3K1 BRAF 25361965 interaction type N/A PTMCode2
RRAS2 BRAF 25361965 interaction type N/A PTMCode2
BRAF RRAS2 25361965 interaction type N/A PTMCode2
BRAF AKT1 25361965 interaction type N/A PTMCode2
YWHAH BRAF 25361965 interaction type N/A PTMCode2
BRAF YWHAH 25361965 interaction type N/A PTMCode2
YWHAQ BRAF 25361965 interaction type N/A PTMCode2
BRAF YWHAQ 25361965 interaction type N/A PTMCode2
PRKCA BRAF 25361965 interaction type N/A PTMCode2
BRAF PRKCA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
OIP5 BRAF 12620389 14525934 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
HSPA8 BRAF 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FBP1 BRAF 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
DELE1 BRAF 25348397 N/A physical interaction ComPPI
SPRY2 BRAF 25348397 N/A physical interaction ComPPI
PAK2 BRAF 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
KRAS BRAF 25348397 N/A physical interaction ComPPI
VIM BRAF 25348397 N/A physical interaction ComPPI
YWHAG BRAF 14525934 15324660 17353931 17979178 24234451 25348397 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
HSP90AB1 BRAF 17979178 22939624 24234451 25348397 association,physical association physical interaction,tandem affinity purification,luminescence based mammalian interactome mapping ComPPI,IntAct
BAD BRAF 25348397 N/A physical interaction ComPPI
MAPK1 BRAF 14525934 14654779 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HRAS BRAF 14525934 16803888 24234451 24441586 25348397 26165597 7706312 9154803 N/A two hybrid,experimental interaction detection,molecular sieving,nuclear magnetic resonance,static light scattering,physical interaction,in vitro ComPPI,HPRD,IntAct
PRKCA BRAF 16810323 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FBXW7 BRAF 25348397 N/A physical interaction ComPPI
ARAF BRAF 17979178 20130576 24234451 25241761 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification,proximity ligation assay ComPPI,IntAct
MAPK3 BRAF 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
PRKCE BRAF 14525934 16810323 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PRKACA BRAF 11510412 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
YWHAB BRAF 10931830 12620389 14525934 15324660 17353931 24234451 24255178 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
YWHAZ BRAF 14525934 15161933 15324660 17353931 17979178 24234451 25348397 26496610 8668348 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
MRAS BRAF 12138204 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HSP90AA1 BRAF 25348397 N/A physical interaction ComPPI
PLD2 BRAF 25348397 N/A physical interaction ComPPI
COPA BRAF 25348397 N/A physical interaction ComPPI
HSPA5 BRAF 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHB BRAF 25348397 N/A physical interaction ComPPI
HSPA1A BRAF 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HSPA1B BRAF 25348397 N/A physical interaction,tandem affinity purification ComPPI
HSP90B1 BRAF 25348397 N/A physical interaction ComPPI
PPP1CA BRAF 25348397 N/A physical interaction ComPPI
MAP2K1 BRAF 14525934 16810323 17979178 23934108 24234451 24746704 25155755 25348397 25437913 25600339 26496610 7731720 8157000 8394352 8621729 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,fluorescence technology,molecular sieving,pull down,surface plasmon resonance,phosphorylation reaction,physical interaction,kinase homogeneous time resolved fluorescence,protein kinase assay,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
RPS6KA2 BRAF 16810323 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRAF3 BRAF 23153539 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KSR2 BRAF 22510884 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PPP2CB BRAF 25348397 N/A physical interaction ComPPI
MAP2K2 BRAF 14525934 17979178 24234451 24746704 25348397 25600339 8668348 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
IQGAP1 BRAF 17563371 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
ZNF510 BRAF 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
RAP1A BRAF 14525934 25348397 9560161 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RAP1B BRAF 25348397 N/A physical interaction ComPPI
YWHAQ BRAF 14525934 15324660 17353931 17979178 24234451 25348397 8668348 association,physical association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,physical interaction,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
NEDD4L BRAF 25348397 N/A physical interaction ComPPI
YWHAH BRAF 14525934 17979178 24234451 25348397 8668348 association two hybrid,physical interaction,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
SFN BRAF 15778465 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
YWHAE BRAF 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RAF1 BRAF 11325826 14525934 16803888 20130576 20141835 22169110 22510884 23680146 23934108 24234451 25155755 25348397 26466569 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,solid phase assay ComPPI,HPRD,IntAct
HSPA4 BRAF 25348397 N/A physical interaction ComPPI
RHEB BRAF 14525934 16803888 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HSPA9 BRAF 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LIMK1 BRAF 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDC37 BRAF 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAP2K7 BRAF 25348397 N/A physical interaction ComPPI
SGK1 BRAF 10869359 11410590 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DNAJB11 BRAF 25348397 N/A physical interaction ComPPI
RAP1GAP BRAF 10854065 11278445 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPKAPK3 BRAF 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PIP5K1A BRAF 25348397 N/A physical interaction ComPPI
GNAS BRAF 25348397 N/A physical interaction ComPPI
RAD50 BRAF 25348397 N/A physical interaction ComPPI
TERF1 BRAF 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BRAF AKT1 10869359 11410590 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
BRAF CCDC88A 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BRAF RNF149 25348397 N/A physical interaction ComPPI
BRAF KSR1 22510884 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRAF BRAP 25348397 N/A physical interaction ComPPI
BRAF RPS6KB2 25348397 N/A physical interaction ComPPI
BRAF HSP90AA2P 25348397 N/A physical interaction ComPPI
BRAF PHKB 17979178 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
BRAF LIPF 25348397 N/A physical interaction ComPPI
BRAF FNIP1 25348397 N/A physical interaction ComPPI
BRAF FNIP2 25348397 N/A physical interaction ComPPI
BRAF RAB3GAP1 25348397 N/A physical interaction ComPPI
BRAF ARMCX3 25348397 N/A physical interaction ComPPI
BRAF KCNC4 25348397 N/A physical interaction ComPPI
BRAF RPTOR 25348397 N/A physical interaction ComPPI
BRAF CYLD 25348397 N/A physical interaction ComPPI
BRAF NRAS 21478863 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
BRAF DNAJB6 25348397 N/A physical interaction ComPPI
BRAF PDCD11 25348397 N/A physical interaction ComPPI
BRAF VANGL1 25348397 N/A physical interaction ComPPI
BRAF DNAJC11 25348397 N/A physical interaction ComPPI
BRAF FKBP5 25348397 N/A physical interaction ComPPI
BRAF HSPA4L 25348397 N/A physical interaction ComPPI
BRAF GNAI2 25348397 N/A physical interaction ComPPI
BRAF DNAJC13 25348397 N/A physical interaction ComPPI
BRAF GNAS 25348397 N/A physical interaction ComPPI
BRAF GNAS 25348397 N/A physical interaction ComPPI
BRAF HSD11B2 25348397 N/A physical interaction ComPPI
BRAF CPNE3 25348397 N/A physical interaction ComPPI
BRAF MYOF 25348397 N/A physical interaction ComPPI
BRAF PIP4K2C 25348397 N/A physical interaction ComPPI
BRAF PGAM1 25348397 N/A physical interaction ComPPI
BRAF DNAJA1 25348397 N/A physical interaction ComPPI
BRAF TIMM50 12620389 24234451 25348397 physical association two hybrid ComPPI,IntAct
BRAF MAP3K1 16810323 16888650 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,protein kinase assay ComPPI,IntAct
BRAF CTSV 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
BRAF HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
BRAF ZNF189 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
UBLCP1 BRAF 25348397 N/A physical interaction ComPPI
FKBPL BRAF 25348397 N/A physical interaction ComPPI
WDR6 BRAF 25348397 N/A physical interaction ComPPI
DNAJC15 BRAF 25348397 N/A physical interaction ComPPI
BRAF BRAF 14525934 16858395 17192257 1748651 19727074 22169110 22510884 24234451 25155755 25437913 7935374 association,physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,cosedimentation in solution,experimental interaction detection,fluorescent resonance energy transfer HPRD,IntAct
BRAF PSME1 27898060 9679960 N/A N/A OmniPath
PRKACA BRAF 10931830 11510412 27898060 stimulant N/A OmniPath
BRAF RB1 15485920 27898060 N/A N/A OmniPath
HRAS BRAF 10545207 16803888 18098337 21779497 24441586 27898060 7706312 8668348 9154803 stimulant N/A OmniPath
BRAF MAP2K1 15485920 16810323 16888650 17979178 18039929 18332145 20212043 23934108 24746704 25155755 25437913 25600339 26496610 27898060 7731720 8157000 8394352 8413257 8621729 stimulant N/A OmniPath
MAP2K1 BRAF 15485920 16810323 16888650 17979178 18332145 20212043 23934108 24746704 25155755 25437913 25600339 26496610 27898060 7731720 8157000 8394352 8413257 8621729 N/A N/A OmniPath
BRAF MAP2K2 18039929 25600339 27898060 8668348 stimulant N/A OmniPath
PEBP1 BRAF 10490027 27898060 stimulant N/A OmniPath
AKT1 BRAF 10869359 11410590 18452278 18669648 19651622 20058876 20068231 20230923 25241761 27898060 inhibition N/A OmniPath
RHEB BRAF 12214276 15150271 16803888 18452278 18669648 18691976 19651622 20068231 20166139 27898060 inhibition N/A OmniPath
BRAF MAPK3 18039929 25241761 27898060 stimulant N/A OmniPath
MAPK3 BRAF 16508002 19933846 21135229 25241761 27898060 inhibition N/A OmniPath
PRMT5 BRAF 21917714 27898060 N/A N/A OmniPath
BRAF TGFB1 19861538 27898060 stimulant N/A OmniPath
RAF1 BRAF 11325826 16803888 18332145 20130576 20141835 20212043 22169110 22510884 23153539 23680146 23934108 25155755 26466569 27898060 N/A N/A OmniPath
BRAF RAF1 11325826 16803888 18332145 20130576 20141835 20212043 22169110 22510884 23153539 23680146 23934108 25155755 26466569 27898060 N/A N/A OmniPath
BRAF EEF1A1 22378069 27898060 N/A N/A OmniPath
NRAS BRAF 21779497 27898060 7935411 stimulant N/A OmniPath
BRAF MAPK1 14654779 18039929 27898060 stimulant N/A OmniPath
MAPK1 BRAF 14654779 16508002 19710016 19933846 27898060 inhibition N/A OmniPath
PAK1 BRAF 10869359 11510412 15710605 27898060 N/A N/A OmniPath
AKT3 BRAF 10869359 11293329 19933846 27898060 inhibition N/A OmniPath
SGK1 BRAF 10869359 11410590 17192257 18452278 18669648 19651622 20058876 20068231 20230923 27898060 N/A N/A OmniPath
AKT2 BRAF 10869359 27898060 inhibition N/A OmniPath
GSK3B BRAF 10869359 11410590 15258589 16093354 27898060 N/A N/A OmniPath
KSR1 BRAF 18332145 22510884 27898060 inhibition N/A OmniPath
RAP1B BRAF 12446733 27898060 stimulant N/A OmniPath
KRAS BRAF 17635919 21779497 27898060 stimulant N/A OmniPath
YWHAH BRAF 10931830 27898060 7744815 8085158 8085159 8668348 stimulant N/A OmniPath
BRAF MAP4K1 1748651 27898060 3043188 7731720 8073291 8385802 stimulant N/A OmniPath

Visualization










  Return