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GENE：POLR1B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLR1B
FullNmae RNA polymerase I subunit B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20454
EnsembleID ENSG00000125630
Uniprot Q9H9Y6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLR1B parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLR1B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLR1B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
POLR1B GO:0001054,GO:0001650,GO:0003677,GO:0005515,GO:0005654,GO:0005694,GO:0005736,GO:0005829,GO:0006360,GO:0007566,GO:0009303,GO:0014029,GO:0017126,GO:0032549,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POLR1B hsa:84172 path:hsa03020 RNA polymerase - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 POLR1B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 POLR1B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 POLR1B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 POLR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA POLR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A POLR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF POLR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 POLR1B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000324096 POLR1B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000031B6ED POLR1B 20371350 23446348 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000047A67D POLR1B 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 POLR1B 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB POLR1B 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 POLR1B 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB POLR1B 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 POLR1B 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 POLR1B 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003E2232 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A POLR1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E POLR1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A POLR1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 POLR1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D POLR1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 POLR1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 POLR1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 POLR1B 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
POLR1B UBTF 25361965 interaction type N/A PTMCode2
UBTF POLR1B 25361965 interaction type N/A PTMCode2
POLR1B POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR1B 25361965 interaction type N/A PTMCode2
POLR1B NME1 25361965 interaction type N/A PTMCode2
NME1 POLR1B 25361965 interaction type N/A PTMCode2
POLR1B POLR2F 25361965 interaction type N/A PTMCode2
POLR2F POLR1B 25361965 interaction type N/A PTMCode2
NME3 POLR1B 25361965 interaction type N/A PTMCode2
POLR1B NME3 25361965 interaction type N/A PTMCode2
POLR2E POLR1B 25361965 interaction type N/A PTMCode2
POLR1B POLR2E 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RPL9 POLR1B 25348397 N/A physical interaction ComPPI
POLR2L POLR1B 25348397 N/A physical interaction ComPPI
CCND1 POLR1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPL11 POLR1B 25348397 N/A physical interaction ComPPI
ACTB POLR1B 25348397 N/A physical interaction ComPPI
TBL3 POLR1B 25348397 N/A physical interaction ComPPI
ERBB2 POLR1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIK3R1 POLR1B 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
NCK1 POLR1B 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SKAP1 POLR1B 25348397 N/A physical interaction ComPPI
GRB2 POLR1B 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
POLR1G POLR1B 25348397 N/A physical interaction ComPPI
POLR1E POLR1B 14525934 15226435 25348397 9254723 N/A experimental interaction detection,in vitro ComPPI,HPRD
NTRK1 POLR1B 25348397 N/A physical interaction ComPPI
RPA1 POLR1B 25348397 N/A physical interaction ComPPI
RPA2 POLR1B 25348397 N/A physical interaction ComPPI
RPA3 POLR1B 25348397 N/A physical interaction ComPPI
NFKBIB POLR1B 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
LDB1 POLR1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ABCE1 POLR1B 25348397 N/A physical interaction ComPPI
ARRB2 POLR1B 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NOLC1 POLR1B 25348397 N/A physical interaction ComPPI
POLR2E POLR1B 25348397 N/A physical interaction ComPPI
CDK7 POLR1B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HDAC6 POLR1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPN21 POLR1B 25348397 N/A physical interaction ComPPI
BAZ1B POLR1B 16514417 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
USP11 POLR1B 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GIT2 POLR1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EIF2S3 POLR1B 25348397 N/A physical interaction ComPPI
CAND1 POLR1B 25348397 N/A physical interaction ComPPI
TRIM25 POLR1B 25348397 N/A physical interaction ComPPI
NOP56 POLR1B 25348397 N/A physical interaction ComPPI
NBN POLR1B 24234451 25064736 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ESR1 POLR1B 11953755 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SMARCA5 POLR1B 16514417 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
EIF3L POLR1B 11592397 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
POLR1A POLR1B 16514417 19214185 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,chromatography technology,physical interaction ComPPI,IntAct
POLR3A POLR1B 25348397 N/A physical interaction ComPPI
POLR2F POLR1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRN3 POLR1B 11250903 14525934 15004009 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
POLR1B POLR1D 25348397 N/A physical interaction ComPPI
POLR1B POLR1D 25348397 N/A physical interaction ComPPI
POLR1B POLR1C 25348397 N/A physical interaction ComPPI
POLR1B TSR1 25348397 N/A physical interaction ComPPI
POLR1B DHX8 25348397 N/A physical interaction ComPPI
POLR1B ACTA1 25348397 N/A physical interaction ComPPI
POLR1B MED20 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
POLR1B AKT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
POLR1B RPL37 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
POLR1B ZNF207 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
POLR1B GPN3 25348397 N/A physical interaction ComPPI
POLR1B POLR1F 25348397 N/A physical interaction ComPPI
POLR1B GFOD1 25348397 N/A physical interaction ComPPI
POLR1B EEFSEC 25348397 N/A physical interaction ComPPI
POLR1B EIF2S3B 25348397 N/A physical interaction ComPPI
POLR1B DDX18 25348397 N/A physical interaction ComPPI
POLR1B POLR2B 25348397 N/A physical interaction ComPPI
POLR1B POLR3B 25348397 N/A physical interaction ComPPI
POLR1B POLR2H 25348397 N/A physical interaction ComPPI
POLR1B POLR2I 25348397 N/A physical interaction ComPPI
POLR1B RPL30 25348397 N/A physical interaction ComPPI
POLR1B RPS5 25348397 N/A physical interaction ComPPI
POLR1B WDR36 25348397 N/A physical interaction ComPPI
POLR1B MYO1C 16514417 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
POLR1B TCOF1 25348397 N/A physical interaction ComPPI
POLR1B FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LZTR1 POLR1B 25348397 N/A physical interaction ComPPI
TAF1D POLR1B 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1B POLR1B 11981034 14525934 N/A experimental interaction detection HPRD
BCAP31 POLR1B 24234451 30021884 physical association cross-linking study IntAct
SIRT7 POLR1B 16618798 27898060 stimulant N/A OmniPath

Visualization










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