GENE：PRDM10
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PRDM10 |
| FullNmae | PR/SET domain 10 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:13995 |
| EnsembleID | ENSG00000170325 |
| Uniprot | Q9NQV6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PRDM10 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PRDM10 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PRDM10 | GO:0000785,GO:0003677,GO:0005515,GO:0005634,GO:0008168,GO:0017053,GO:0032259,GO:0045944,GO:0045944,GO:0046872 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | PRDM10 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | PRDM10 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | PRDM10 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | PRDM10 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PRDM10 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | PRDM10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002C02E4 | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003003B4 | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042B108 | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B0D1E | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004407DC | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | PRDM10 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EC3B | PRDM10 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFEC1 | PRDM10 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017EA6A | PRDM10 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000277201 | PRDM10 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CD44 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| REL | PRDM10 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| RAP1GDS1 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| SDC2 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| CUL1 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| SDC1 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| CASQ2 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| BAP1 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| FOXK2 | PRDM10 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| PPAN | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| PRDM5 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |