GENE：RAB8B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RAB8B |
| FullNmae | RAB8B, member RAS oncogene family |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:30273 |
| EnsembleID | ENSG00000166128 |
| Uniprot | Q92930 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RAB8B | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RAB8B | GO:0003924,GO:0003924,GO:0005102,GO:0005515,GO:0005525,GO:0005768,GO:0005778,GO:0005886,GO:0006904,GO:0008021,GO:0009306,GO:0017157,GO:0019003,GO:0019882,GO:0030140,GO:0030670,GO:0030911,GO:0031346,GO:0032456,GO:0045046,GO:0045335,GO:0048210,GO:0048471,GO:0051286,GO:0051461,GO:0055038,GO:0070062,GO:0072659,GO:0150115 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| RAB8B | hsa:51762 | path:hsa04530 | Tight junction - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | RAB8B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | RAB8B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | RAB8B | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | RAB8B | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | RAB8B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | RAB8B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RAB8B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RAB8B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RAB8B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RAB8B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RAB8B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000CF1D2 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00000F31F4 | RAB8B | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | RAB8B | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000DDD35 | RAB8B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000006FDD4 | RAB8B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003E1A9 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008DA94 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A25B | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | RAB8B | 20371350 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A8BB2 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000496C56 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000319E1 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037B2E0 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004283FE | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AEA5 | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B13F | RAB8B | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | RAB8B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | RAB8B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000195F5B | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A71AD | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000285DCB | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFEC1 | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000E601 | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009A9A2 | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A9CF | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ECEE4 | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | RAB8B | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VIM | RAB8B | 25361965 | interaction type | N/A | PTMCode2 |
| RAB8B | VIM | 25361965 | interaction type | N/A | PTMCode2 |
| CDH1 | RAB8B | 25361965 | interaction type | N/A | PTMCode2 |
| RAB8B | CDH1 | 25361965 | interaction type | N/A | PTMCode2 |
| JUP | RAB8B | 25361965 | interaction type | N/A | PTMCode2 |
| RAB8B | JUP | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VIM | RAB8B | 12639940 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| RABIF | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| TUBB | RAB8B | 25348397 | N/A | physical interaction,in vivo | ComPPI |
| UBL4A | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| ACTB | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| OCLN | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| GDI2 | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RAB8A | RAB8B | 24234451 25348397 26824392 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SYTL4 | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RPH3A | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| GRB2 | RAB8B | 17474147 24234451 25348397 | physical association | peptide array | ComPPI,IntAct |
| FLNC | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| ITGB1 | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| FLNA | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| JUP | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RAB7A | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| TUBG1 | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | RAB8B | 25348397 | N/A | physical interaction,in vivo | ComPPI |
| PXN | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RALA | RAB8B | 10889189 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| TUBA4A | RAB8B | 12639940 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CHM | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RAB3IP | RAB8B | 12221131 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| MICALL1 | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RAB5A | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| GDI1 | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RAP1A | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RAP1B | RAB8B | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | CDH2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | TES | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | CTNNB1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | TJP1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | TUBA1A | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | APP | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | RAB1C | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | RAB1B | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | HSD17B10 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | NEDD8 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | RAB5C | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | MICALL2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | MICAL3 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | UHRF1BP1L | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | NARS2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | CHML | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | MOCS1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | RAB13 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | NOCT | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | CTU2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | BIN1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | EHBP1L1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8B | PTBP3 | 22575643 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| RAB8B | TUBB2A | 12639940 14525934 | N/A | experimental interaction detection | HPRD |
| RAB8B | OTOF | 18772196 27898060 | N/A | N/A | OmniPath |