GENE:SEC24D
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SEC24D |
| FullNmae | SEC24 homolog D, COPII coat complex component |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10706 |
| EnsembleID | ENSG00000150961 |
| Uniprot | O94855 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SEC24D | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SEC24D | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SEC24D | GO:0000149,GO:0000149,GO:0001701,GO:0005515,GO:0005789,GO:0005829,GO:0006886,GO:0006888,GO:0006888,GO:0008270,GO:0008270,GO:0012507,GO:0030127,GO:0030127,GO:0030127,GO:0043231,GO:0070971,GO:0090110,GO:0090110 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SEC24D | hsa:9871 | path:hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
| SEC24D | hsa:9871 | path:hsa05130 | Pathogenic Escherichia coli infection - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SEC24D | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | SEC24D | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | SEC24D | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | SEC24D | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | SEC24D | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SEC24D | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000075ABF4 | SEC24D | 19336450 | rna interference,inhibition | western blot,quantitative reverse transcription pcr | miRSponge |
| URS000075ABF4 | SEC24D | 19336450 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr | TarBase |
| URS0000237AF9 | SEC24D | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000F31F4 | SEC24D | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | SEC24D | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000028DE3F | SEC24D | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000451A1 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001AFC71 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D2F5 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMO4 | SEC24D | 14525934 15231748 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| SEC23B | SEC24D | 14525934 16189514 21516116 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
| SH3KBP1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| TMA16 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| SF3B4 | SEC24D | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CD2AP | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| ARFIP1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| WWP2 | SEC24D | 21516116 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PXN | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | SEC24D | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| XPO1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| GTF2E2 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| CDK16 | SEC24D | 16091426 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| ERN1 | SEC24D | 24234451 25348397 25742138 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| H1-2 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| VPS29 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| PLEKHO1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| SHMT2 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| RSU1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| SEC24A | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
| SEC24D | TMED2 | 20427317 24234451 25348397 | physical association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| SEC24D | SEC23IP | 10097109 10330397 10720463 10749860 10753972 11535824 12239560 12408798 12671686 12778054 21532587 24947508 27898060 8930902 | N/A | N/A | OmniPath |
