GENE:SEC24D
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SEC24D |
FullNmae | SEC24 homolog D, COPII coat complex component |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:10706 |
EnsembleID | ENSG00000150961 |
Uniprot | O94855 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SEC24D | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
SEC24D | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SEC24D | GO:0000149,GO:0000149,GO:0001701,GO:0005515,GO:0005789,GO:0005829,GO:0006886,GO:0006888,GO:0006888,GO:0008270,GO:0008270,GO:0012507,GO:0030127,GO:0030127,GO:0030127,GO:0043231,GO:0070971,GO:0090110,GO:0090110 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
SEC24D | hsa:9871 | path:hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
SEC24D | hsa:9871 | path:hsa05130 | Pathogenic Escherichia coli infection - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | SEC24D | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | SEC24D | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | SEC24D | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | SEC24D | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
TFAP2C | SEC24D | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | SEC24D | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | SEC24D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000075ABF4 | SEC24D | 19336450 | rna interference,inhibition | western blot,quantitative reverse transcription pcr | miRSponge |
URS000075ABF4 | SEC24D | 19336450 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr | TarBase |
URS0000237AF9 | SEC24D | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000F31F4 | SEC24D | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | SEC24D | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000028DE3F | SEC24D | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00000451A1 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001AFC71 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075C1E1 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075D2F5 | SEC24D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
LMO4 | SEC24D | 14525934 15231748 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
SEC23B | SEC24D | 14525934 16189514 21516116 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
SH3KBP1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
TMA16 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
SF3B4 | SEC24D | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
CD2AP | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
ARFIP1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
NTRK1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
WWP2 | SEC24D | 21516116 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
PXN | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
EWSR1 | SEC24D | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
XPO1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
GTF2E2 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
CDK16 | SEC24D | 16091426 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
ERN1 | SEC24D | 24234451 25348397 25742138 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
H1-2 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
VPS29 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
PLEKHO1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
SHMT2 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
RSU1 | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
SEC24A | SEC24D | 25348397 | N/A | physical interaction | ComPPI |
SEC24D | TMED2 | 20427317 24234451 25348397 | physical association | anti tag coimmunoprecipitation | ComPPI,IntAct |
SEC24D | SEC23IP | 10097109 10330397 10720463 10749860 10753972 11535824 12239560 12408798 12671686 12778054 21532587 24947508 27898060 8930902 | N/A | N/A | OmniPath |