Gene Information gene info

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GENE：SLF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLF2
FullNmae SMC5-SMC6 complex localization factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17814
EnsembleID ENSG00000119906
Uniprot Q8IX21

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLF2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLF2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLF2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLF2 GO:0000724,GO:0000781,GO:0000785,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0006974,GO:0006974,GO:0016605,GO:0016925,GO:0030915,GO:0031334,GO:0031625,GO:0032204,GO:0034184,GO:0035861,GO:0035861,GO:0043231,GO:0044877,GO:0140588,GO:1990166,GO:1990166,GO:2000781,GO:2000781

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 SLF2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SLF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC SLF2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SLF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 SLF2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 SLF2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 SLF2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CALM1 SLF2 25348397 N/A physical interaction ComPPI
OPTN SLF2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
PSMA1 SLF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAD18 SLF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ITGA1 SLF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 SLF2 25348397 N/A physical interaction ComPPI
BRCA1 SLF2 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
SMC6 SLF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLF2 TRIM14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
H2BC20P SLF2 24234451 30021884 physical association cross-linking study IntAct

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