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GENE：SREK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SREK1
FullNmae splicing regulatory glutamic acid and lysine rich protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17882
EnsembleID ENSG00000153914
Uniprot Q8WXA9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SREK1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SREK1 GO:0003723,GO:0005515,GO:0005654,GO:0005681,GO:0006397,GO:0008380,GO:0016607

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DDX17 SREK1 14559993 23180781 physical association pull down InnateDB
SREK1 YBX1 14559993 23180781 physical association pull down InnateDB
SAFB SREK1 14559993 23180781 physical association pull down InnateDB
SREK1 RBMXL2 14559993 23180781 physical association pull down InnateDB
SREK1 SRSF7 14559993 23180781 physical association pull down InnateDB
SRPK1 SREK1 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB
SRPK2 SREK1 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 SREK1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SREK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 SREK1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SREK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SREK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SREK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SREK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SREK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SREK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D SREK1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00000A07C1 SREK1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000D5659 SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF SREK1 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 SREK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 SREK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 SREK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 SREK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB SREK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000157FBE SREK1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC SREK1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SF3A3 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PIN1 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
HNRNPK SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TXLNA SREK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDC5L SREK1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPC SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NPM1 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RPL37A SREK1 25348397 N/A physical interaction ComPPI
SNRPD1 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NIFK SREK1 25348397 N/A physical interaction ComPPI
INO80B SREK1 25348397 N/A physical interaction ComPPI
RACK1 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RRS1 SREK1 25348397 N/A physical interaction ComPPI
DDX17 SREK1 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
GPRASP2 SREK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBM39 SREK1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SFPQ SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NTRK1 SREK1 25348397 N/A physical interaction ComPPI
PRPF40A SREK1 25348397 N/A two hybrid ComPPI
YBX1 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PARP1 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 CD8A 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 DDX3X 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 RBMX 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 HNRNPA2B1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRSF1 10757789 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRSF2 10757789 11991645 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRSF5 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
SREK1 HNRNPH1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SNRPD3 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 HNRNPD 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 TRA2B 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 HNRNPU 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SAFB 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRSF8 14525934 14559993 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SREK1 SRSF3 10757789 11991645 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 PABPC4 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 EFTUD2 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SSRP1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 PABPC1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRSF10 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 HNRNPA3 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 CSNK2A1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRPK3 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 THRAP3 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRSF7 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
SREK1 SRSF4 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SRSF6 10757789 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 ZRANB2 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SF3B3 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SH3GLB2 14525934 14559993 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SREK1 SRPK1 14525934 14559993 23602568 24234451 25348397 phosphorylation reaction two hybrid,experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SREK1 ELAVL1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SUPT16H 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 DGKA 14525934 14559993 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SREK1 DDX39B 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 HNRNPA1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 RNPS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SREK1 DGKD 25348397 N/A physical interaction ComPPI
SREK1 TARBP1 25348397 N/A physical interaction ComPPI
SREK1 SRSF9 25348397 N/A physical interaction ComPPI
SREK1 C1QBP 25348397 N/A physical interaction ComPPI
SREK1 NCL 14525934 14559993 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
SREK1 HNRNPCL1 25348397 N/A physical interaction ComPPI
SREK1 CUL1 25348397 N/A physical interaction ComPPI
SREK1 VPS33A 25348397 N/A physical interaction ComPPI
SREK1 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
SREK1 SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
SREK1 LIN28A 25348397 N/A physical interaction ComPPI
SREK1 SRSF11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SREK1 H1-1 25348397 N/A physical interaction ComPPI
SREK1 LUC7L2 25348397 N/A physical interaction ComPPI
SREK1 PNN 25348397 N/A physical interaction ComPPI
SREK1 JMJD6 25348397 N/A physical interaction ComPPI
SREK1 PUF60 25348397 N/A physical interaction ComPPI
SREK1 RBM25 25348397 N/A physical interaction ComPPI
SREK1 SNRNP40 25348397 N/A physical interaction ComPPI
SREK1 CEP135 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SREK1 CEP290 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SREK1 SSX2IP 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SREK1 SPATA1 25348397 N/A physical interaction ComPPI
SREK1 H1-6 25348397 N/A physical interaction ComPPI
SREK1 CDX1 25348397 N/A physical interaction ComPPI
SREK1 CHCHD10 25348397 N/A physical interaction ComPPI
SREK1 PAIP1 25348397 N/A physical interaction ComPPI
RBM10 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ILF2 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SREK1 SREK1 10757789 14525934 14559993 24234451 25416956 physical association experimental interaction detection,two hybrid array,two hybrid HPRD,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B8479 SREK1 27087310 direct interaction,inhibition N/A NPInter

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