Gene Information gene info

GENE:STX5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STX5
FullNmae syntaxin 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11440
EnsembleID ENSG00000162236
Uniprot Q13190

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STX5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
STX5 GO:0000139,GO:0000139,GO:0000149,GO:0005484,GO:0005484,GO:0005515,GO:0005789,GO:0005794,GO:0005829,GO:0006886,GO:0006888,GO:0006906,GO:0012505,GO:0012507,GO:0031201,GO:0031201,GO:0031982,GO:0033116,GO:0034498,GO:0042147,GO:0045296,GO:0045732,GO:0048278,GO:0048280,GO:0090166,GO:1903358

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STX5 hsa:6811 path:hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 STX5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 STX5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 STX5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXA1 STX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 STX5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
STX5 STXBP1 25361965 interaction type N/A PTMCode2
STXBP1 STX5 25361965 interaction type N/A PTMCode2
STX5 NSF 25361965 interaction type N/A PTMCode2
NSF STX5 25361965 interaction type N/A PTMCode2
BET1 STX5 25361965 interaction type N/A PTMCode2
STX5 BET1 25361965 interaction type N/A PTMCode2
NAPA STX5 25361965 interaction type N/A PTMCode2
STX5 NAPA 25361965 interaction type N/A PTMCode2
GOSR2 STX5 25361965 interaction type N/A PTMCode2
STX5 GOSR2 25361965 interaction type N/A PTMCode2
SNAP23 STX5 25361965 interaction type N/A PTMCode2
STX5 SNAP23 25361965 interaction type N/A PTMCode2
SEC24B STX5 25361965 interaction type N/A PTMCode2
STX5 SEC24B 25361965 interaction type N/A PTMCode2
STXBP2 STX5 25361965 interaction type N/A PTMCode2
STX5 STXBP2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GPANK1 STX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GET3 STX5 25348397 N/A physical interaction ComPPI
SEC22A STX5 25348397 N/A physical interaction ComPPI
VAMP5 STX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNAP29 STX5 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX12 STX5 25348397 N/A physical interaction ComPPI
MAGEA6 STX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EMD STX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNA STX5 25348397 N/A physical interaction ComPPI
KASH5 STX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
JAGN1 STX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USO1 STX5 25348397 N/A physical interaction,in vitro ComPPI
CANX STX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDH1 STX5 25348397 N/A physical interaction ComPPI
BAG6 STX5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SNAP25 STX5 25348397 N/A physical interaction ComPPI
SNAP23 STX5 25348397 N/A physical interaction ComPPI
STXBP1 STX5 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
EVC2 STX5 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PDHA1 STX5 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
STX4 STX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NSF STX5 25348397 N/A physical interaction ComPPI
STX1A STX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAPB STX5 25348397 N/A physical interaction ComPPI
NAPA STX5 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
STX8 STX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COPS6 STX5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HAP1 STX5 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
STX7 STX5 25348397 N/A physical interaction ComPPI
STX3 STX5 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EBP STX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IMMT STX5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LRIF1 STX5 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TNPO3 STX5 25348397 N/A physical interaction ComPPI
ARFGAP1 STX5 25348397 N/A physical interaction ComPPI
HMMR STX5 25348397 N/A physical interaction ComPPI
RIF1 STX5 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
STX5 GOSR1 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
STX5 GOSR2 11035026 14525934 24234451 25348397 9094723 9647643 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
STX5 SEC22B 11035026 15029241 22153078 24234451 24705552 25348397 27898060 9166403 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,in vitro ComPPI,IntAct,OmniPath
STX5 NSFL1C 12473691 14525934 25348397 9506515 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
STX5 SCFD1 12506202 14525934 14565970 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
STX5 VCPIP1 12473691 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
STX5 BET1 14525934 24234451 25348397 29568061 9094723 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo,proximity-dependent biotin identification ComPPI,HPRD,IntAct
STX5 APLP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
STX5 TP53 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
STX5 STX17 25348397 N/A physical interaction ComPPI
STX5 BET1L 25348397 N/A physical interaction ComPPI
STX5 YKT6 25348397 N/A physical interaction ComPPI
STX5 VTI1B 25348397 N/A physical interaction ComPPI
STX5 LNX1 25348397 N/A physical interaction ComPPI
STX5 TMED9 25348397 N/A physical interaction ComPPI
STX5 TACC1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STX5 NAPB 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STX5 STX6 25348397 N/A physical interaction ComPPI
STX5 USE1 25348397 N/A physical interaction ComPPI
STX5 SRPRB 25348397 N/A physical interaction ComPPI
STX5 RBM26 25348397 N/A physical interaction ComPPI
STX5 FAAP100 25348397 N/A physical interaction ComPPI
STX5 CLEC12A 25348397 N/A physical interaction ComPPI
STX5 TMEM171 25348397 N/A physical interaction ComPPI
STX5 STX18 25348397 N/A physical interaction ComPPI
STX5 DTNBP1 25348397 N/A physical interaction ComPPI
STX5 CHST9 25348397 N/A physical interaction ComPPI
STX5 LPAR1 25348397 N/A physical interaction ComPPI
STX5 NUP160 25348397 N/A physical interaction ComPPI
STX5 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STX5 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STX5 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STX5 INSYN2A 25348397 N/A physical interaction ComPPI
STX5 VAMP4 25348397 N/A physical interaction ComPPI
STX5 TMEM266 25348397 N/A physical interaction ComPPI
STX5 HAUS1 25348397 N/A physical interaction ComPPI
STX5 CSGALNACT2 25348397 N/A physical interaction ComPPI
STX5 IL4R 25348397 N/A physical interaction ComPPI
STX5 CCDC107 25348397 N/A physical interaction ComPPI
STX5 ACADS 25348397 N/A physical interaction ComPPI
STX5 CNGA3 25348397 N/A physical interaction ComPPI
STX5 TRPM8 25348397 N/A physical interaction ComPPI
STX5 DKK3 25348397 N/A physical interaction ComPPI
STX5 MANSC1 25348397 N/A physical interaction ComPPI
STX5 IL20RA 25348397 N/A physical interaction ComPPI
STX5 COG4 19536132 24234451 25348397 physical association pull down ComPPI,IntAct
STX5 SNAP47 24234451 25348397 26359495 physical association anti tag coimmunoprecipitation ComPPI,IntAct
STX5 REEP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 AARD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 HSD17B11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 RETREG3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 STING1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 GPR152 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 FAM209A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 CREB3L3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 LRRC4C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX5 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STX5 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB STX5 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
STX5 VCP 12473691 14525934 9506515 N/A experimental interaction detection HPRD
STX5 PKD2 18836075 27898060 inhibition N/A OmniPath

Visualization