Gene Information gene info

GENE:TNPO2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNPO2
FullNmae transportin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19998
EnsembleID ENSG00000105576
Uniprot O14787

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNPO2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNPO2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TNPO2 GO:0005515,GO:0005634,GO:0005737,GO:0006606,GO:0008139,GO:0031267,GO:0061608

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNPO2 hsa:30000 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TNPO2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TNPO2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TNPO2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 TNPO2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001597DC TNPO2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000021D7C8 TNPO2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001F0C23 TNPO2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002B2B5C TNPO2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00003D5391 TNPO2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000028FD1A TNPO2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 TNPO2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 TNPO2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AAAFF TNPO2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C TNPO2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000011A030 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000023F008 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 TNPO2 20371350 21572407 22012620 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000192A75 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 TNPO2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 TNPO2 20371350 21572407 22012620 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000047A8F TNPO2 20371350 21572407 22012620 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000032015F TNPO2 20371350 21572407 22012620 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075ABF4 TNPO2 20371350 22012620 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000047A67D TNPO2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C TNPO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 TNPO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 TNPO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED TNPO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 TNPO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE TNPO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000001C659 TNPO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005F305A TNPO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 TNPO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 TNPO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 TNPO2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237E04 TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D1FC TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000AD002 TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E226A TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000021202F TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004F859B TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000036AFF1 TNPO2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000381CEC TNPO2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NUP98 TNPO2 25361965 interaction type N/A PTMCode2
TNPO2 NUP98 25361965 interaction type N/A PTMCode2
RAN TNPO2 25361965 interaction type N/A PTMCode2
TNPO2 RAN 25361965 interaction type N/A PTMCode2
ELAVL1 TNPO2 25361965 interaction type N/A PTMCode2
TNPO2 ELAVL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EXOC5 TNPO2 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VASN TNPO2 25348397 N/A physical interaction ComPPI
BYSL TNPO2 25348397 N/A physical interaction ComPPI
CRYAB TNPO2 25348397 N/A physical interaction ComPPI
PNMA5 TNPO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TUBB TNPO2 25348397 N/A physical interaction ComPPI
TMA16 TNPO2 25348397 N/A physical interaction ComPPI
RAN TNPO2 25348397 N/A physical interaction ComPPI
CD44 TNPO2 25348397 N/A physical interaction ComPPI
NTRK1 TNPO2 25348397 N/A physical interaction ComPPI
NME1 TNPO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EPHA1 TNPO2 25348397 N/A physical interaction ComPPI
NUP98 TNPO2 25348397 N/A physical interaction ComPPI
XPO1 TNPO2 25348397 N/A physical interaction ComPPI
TNFSF13B TNPO2 25348397 N/A physical interaction ComPPI
CAMK2D TNPO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EGFR TNPO2 25348397 N/A physical interaction ComPPI
PTPRE TNPO2 25348397 N/A physical interaction ComPPI
RP2 TNPO2 25348397 N/A physical interaction ComPPI
HTR2C TNPO2 25348397 N/A physical interaction ComPPI
A1CF TNPO2 12896982 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CD274 TNPO2 25348397 N/A physical interaction ComPPI
FCGRT TNPO2 25348397 N/A physical interaction ComPPI
BCAM TNPO2 25348397 N/A physical interaction ComPPI
GYPB TNPO2 25348397 N/A physical interaction ComPPI
ELAVL1 TNPO2 11729309 14525934 14981248 15037768 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
EDNRB TNPO2 25348397 N/A physical interaction ComPPI
TERF1 TNPO2 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
APIP TNPO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF11 TNPO2 25348397 N/A physical interaction ComPPI
TNPO2 TCL1B 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TNPO2 PTP4A3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TNPO2 NXF1 12384575 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TNPO2 KLHL2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNPO2 C1ORF94 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNPO2 MOV10 25348397 N/A physical interaction ComPPI
TNPO2 ADORA3 25348397 N/A physical interaction ComPPI
TNPO2 VSIG2 25348397 N/A physical interaction ComPPI
TNPO2 CA14 25348397 N/A physical interaction ComPPI
TNPO2 CD68 25348397 N/A physical interaction ComPPI
TNPO2 NT5E 25348397 N/A physical interaction ComPPI
TNPO2 PNKD 25348397 N/A physical interaction ComPPI
TNPO2 LPAR6 25348397 N/A physical interaction ComPPI
TNPO2 LYPD3 25348397 N/A physical interaction ComPPI
TNPO2 CD200R1 25348397 N/A physical interaction ComPPI
TNPO2 MICA 25348397 N/A physical interaction ComPPI
TNPO2 PTGER3 25348397 N/A physical interaction ComPPI
TNPO2 ARL13B 25348397 N/A physical interaction ComPPI
TNPO2 SCN2B 25348397 N/A physical interaction ComPPI
TNPO2 TRARG1 25348397 N/A physical interaction ComPPI
TNPO2 IKBKG 25348397 N/A physical interaction ComPPI
TNPO2 SIGLECL1 25348397 N/A physical interaction ComPPI
TNPO2 FZD10 25348397 N/A physical interaction ComPPI
TNPO2 PACC1 25348397 N/A physical interaction ComPPI
TNPO2 CHRM4 25348397 N/A physical interaction ComPPI
TNPO2 LRRC4 25348397 N/A physical interaction ComPPI
TNPO2 FAM234B 25348397 N/A physical interaction ComPPI
TNPO2 FAM174A 25348397 N/A physical interaction ComPPI
TNPO2 TMEM108 25348397 N/A physical interaction ComPPI
TNPO2 VSIG1 25348397 N/A physical interaction ComPPI
TNPO2 DLK2 25348397 N/A physical interaction ComPPI
TNPO2 CD83 25348397 N/A physical interaction ComPPI
TNPO2 NCR3LG1 25348397 N/A physical interaction ComPPI
TNPO2 G3BP1 25348397 N/A physical interaction ComPPI
TNPO2 PIK3CD 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TNPO2 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
COMTD1 TNPO2 25348397 N/A physical interaction ComPPI

Visualization