Gene Information gene info

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GENE：UROS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UROS
FullNmae uroporphyrinogen III synthase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12592
EnsembleID ENSG00000188690
Uniprot P10746

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UROS autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UROS GO:0004852,GO:0004852,GO:0004852,GO:0005542,GO:0005739,GO:0005829,GO:0005829,GO:0006780,GO:0006780,GO:0006782,GO:0006783,GO:0006783,GO:0006783,GO:0070541,GO:0071243,GO:0071418

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UROS hsa:7390 path:hsa00860 Porphyrin metabolism - Homo sapiens (human)
UROS hsa:7390 path:hsa01100 Metabolic pathways - Homo sapiens (human)
UROS hsa:7390 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 UROS 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UROS 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UROS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UROS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UROS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A UROS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UROS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UROS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFIC UROS N/A trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 UROS N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E96DA UROS 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000411752 UROS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD UROS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 UROS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001481F9 UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000221168 UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CC20C UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075BDAA UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EC1BE UROS 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BOLA1 UROS 25348397 N/A physical interaction ComPPI
COPS5 UROS 25348397 N/A physical interaction ComPPI
EED UROS 25348397 N/A physical interaction ComPPI
TRIM25 UROS 25348397 N/A physical interaction ComPPI
ATG7 UROS 25348397 N/A physical interaction ComPPI
TCEAL1 UROS 25348397 N/A physical interaction ComPPI
UROS GCLM 25348397 N/A physical interaction ComPPI

Visualization










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