GENE:USP36
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | USP36 |
| FullNmae | ubiquitin specific peptidase 36 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20062 |
| EnsembleID | ENSG00000055483 |
| Uniprot | Q9P275 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| USP36 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| USP36 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| USP36 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| USP36 | GO:0003723,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006325,GO:0007000,GO:0016242,GO:0016579,GO:0016579,GO:0016579,GO:0016607,GO:0031647,GO:0042981,GO:0050821,GO:1903146,GO:1903955,GO:1990380,GO:2000232,GO:2000232 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | USP36 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | USP36 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | USP36 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | USP36 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | USP36 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000148B91 | USP36 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003D5391 | USP36 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000016C318 | USP36 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000B0E50 | USP36 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005DEC41 | USP36 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BF7F9 | USP36 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000209F04 | USP36 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000519450 | USP36 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NPM1 | USP36 | 19679658 25348397 26186194 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| TBL3 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RPL10 | USP36 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FBXW7 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| NUP85 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| UBC | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| PARP1 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MYC | USP36 | 21150319 24234451 25348397 25775507 27898060 | association | physical interaction,tandem affinity purification | ComPPI,IntAct,OmniPath |
| HNRNPU | USP36 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RPS6 | USP36 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PJA1 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| FOXA1 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| SRPK2 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| IFI16 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| STK25 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SHPRH | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FBL | USP36 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PPP6R3 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SOD2 | USP36 | 21268071 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| PWP2 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CELSR2 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| FANCI | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CHD4 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GNL2 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DDX41 | USP36 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TRIM26 | USP36 | 25348397 | N/A | physical interaction | ComPPI |
| USP36 | PPM1G | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP36 | IFRD2 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP36 | WDR3 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP36 | DHX33 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| USP36 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
| MKI67 | USP36 | 24234451 26949251 | association | anti tag coimmunoprecipitation | IntAct |
