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GENE：ATP6V0C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6V0C
FullNmae ATPase H+ transporting V0 subunit c
LocusType gene with protein product
Status Approved
HGNC_id HGNC:855
EnsembleID ENSG00000185883
Uniprot P27449

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6V0C lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
ATP6V0C lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
ATP6V0C immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V0C autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V0C autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP6V0C GO:0000139,GO:0000220,GO:0005515,GO:0005765,GO:0005765,GO:0005765,GO:0005886,GO:0005886,GO:0005925,GO:0007035,GO:0007042,GO:0010008,GO:0010008,GO:0015986,GO:0016020,GO:0016241,GO:0030177,GO:0030665,GO:0030670,GO:0030672,GO:0031625,GO:0033176,GO:0035577,GO:0046933,GO:0046961,GO:0048388,GO:0051452,GO:0061795,GO:0070062,GO:0070821,GO:0101003,GO:1902495,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6V0C hsa:527 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa04142 Lysosome - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa04966 Collecting duct acid secretion - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa05152 Tuberculosis - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6V0C hsa:527 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATP6V0C EDA 23180781 25416956 physical association two hybrid InnateDB
ATP6V0C MSR1 23180781 25416956 physical association two hybrid InnateDB
ATP6V0C PSMA3 23180781 25416956 physical association two hybrid InnateDB
ATP6V0C SMIM3 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ATP6V0C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ATP6V0C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004505E4 ATP6V0C 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ZCCHC12 ATP6V0C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMIM3 ATP6V0C 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TMEM199 ATP6V0C 25348397 N/A physical interaction ComPPI
ATP5F1B ATP6V0C 25348397 N/A physical interaction ComPPI
LMNA ATP6V0C 25348397 N/A physical interaction ComPPI
GPR25 ATP6V0C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C CERS2 11543633 14525934 21988832 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ATP6V0C MARK3 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ATP6V0C ARF6 14525934 16415858 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ATP6V0C RNF182 25348397 N/A physical interaction ComPPI
ATP6V0C CLIC1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ATP6V0C EDA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATP6V0C MSR1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATP6V0C PSMA3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATP6V0C ATP6AP2 25348397 N/A physical interaction ComPPI
ATP6V0C TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6V0C CREB3 25348397 N/A physical interaction ComPPI
ATP6V0C MDFI 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP6V0C ATP6V0D1 25348397 N/A physical interaction ComPPI
ATP6V0C ATP6V0A2 25348397 N/A physical interaction ComPPI
ATP6V0C ATP6V0D2 25348397 N/A physical interaction ComPPI
ATP6V0C KIAA2013 25348397 N/A physical interaction ComPPI
ATP6V0C VMA21 25348397 N/A physical interaction ComPPI
ATP6V0C MTUS2 25348397 N/A physical interaction ComPPI
ATP6V0C FAM241B 25348397 N/A physical interaction ComPPI
ATP6V0C PTPRE 25348397 N/A physical interaction ComPPI
ATP6V0C PDGFRB 1334459 24234451 25348397 27898060 physical association coimmunoprecipitation ComPPI,IntAct,OmniPath
ATP6V0C VSIR 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C NIPAL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C ERH 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C CD69 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C FAM210B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C CLEC14A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C TMEM139 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C PI16 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C EVI2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C RETREG3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C SLC7A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C SLC35E3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C CD53 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C DNAJC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C EDA2R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C KLRC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C LRRC25 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C CPLX4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C HSD17B13 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C PDCD1LG2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C CD79A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C SCN3B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C FFAR2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C SUSD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C GPR152 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C CLEC17A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C SSMEM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C MCEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C GPR42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C STOM 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C TMEM9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HTR2C ATP6V0C 24234451 28298427 physical association ubiquitin reconstruction IntAct
ATP6V0C DRD2 24234451 28298427 physical association ubiquitin reconstruction IntAct

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