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GENE：CXCL8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CXCL8
FullNmae C-X-C motif chemokine ligand 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6025
EnsembleID ENSG00000169429
Uniprot P10145

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CXCL8 necroptosis 40138999 The CXCL8/C3AR1 axis, validated by Transwell and co-immunoprecipitation assays, is crucial for communication between necroptosis and neutrophil chemotaxis in DPCs. retulator signature
CXCL8 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CXCL8 GO:0001525,GO:0002237,GO:0005153,GO:0005515,GO:0005576,GO:0005615,GO:0006935,GO:0006954,GO:0006954,GO:0007165,GO:0007186,GO:0008009,GO:0008009,GO:0008009,GO:0008201,GO:0008285,GO:0010628,GO:0010629,GO:0019722,GO:0030155,GO:0030593,GO:0030593,GO:0030593,GO:0031328,GO:0031623,GO:0034976,GO:0035556,GO:0042119,GO:0042119,GO:0044344,GO:0045091,GO:0045236,GO:0045744,GO:0045766,GO:0048566,GO:0050930,GO:0060354,GO:0061844,GO:0070098,GO:0071222,GO:0071222,GO:0071347,GO:0071356,GO:0090023,GO:2000535

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CXCL8 hsa:3576 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04218 Cellular senescence - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05131 Shigellosis - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05132 Salmonella infection - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05133 Pertussis - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05134 Legionellosis - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05135 Yersinia infection - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05142 Chagas disease - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05144 Malaria - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05146 Amoebiasis - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05161 Hepatitis B - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05164 Influenza A - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05200 Pathways in cancer - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05219 Bladder cancer - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)
CXCL8 hsa:3576 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CXCL8 CXCR2 12628493 15079071 17533374 17784835 17916596 18555777 18555778 18633355 18980965 19190236 21328342 21847358 23180781 23869868 24406209 25922287 26192618 26201938 27557510 7592830 8245475 8662882 8702798 9126332 9464567 9485196 association,physical association isothermal titration calorimetry,competition binding ACSN,InnateDB
ANGPT1 CXCL8 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26192618 26552706 8551221 interaction type N/A ACSN
GRB2 CXCL8 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 CXCL8 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26192618 26552706 8551221 interaction type N/A ACSN
RELA CXCL8 15079071 15536066 17550372 19171876 23180781 23430059 24634218 24761865 26192618 8383323 9743347 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
KLRG1 CXCL8 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 26192618 27557510 9751747 interaction type N/A ACSN
PTPN11 CXCL8 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 26192618 27557510 9751747 interaction type N/A ACSN
IKBKB CXCL8 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 IRF1 15057743 18198374 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
CXCL8 RELA 12820969 14527995 15057743 15223809 15485852 15489293 15494311 15531761 17447895 18045535 18198374 18694960 19064995 19173296 19837667 19903813 21131967 21399639 23180781 24129565 8413306 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
CXCL8 NFKB1 15057743 15223809 15494311 18198374 19837667 23180781 8413306 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
FOS CXCL8 15057743 19173296 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
CXCL8 JUN 15057743 18198374 19064995 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
EP300 CXCL8 15286281 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 HDAC3 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 NCOR2 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 H3-4 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 CHUK 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 RELB 17823304 23180781 physical association electrophoretic mobility supershift assay InnateDB
AHR CXCL8 17823304 23180781 physical association electrophoretic mobility supershift assay InnateDB
CXCL8 REL 23180781 8413306 physical association electrophoretic mobility supershift assay InnateDB
CXCL8 CEBPB 19064995 23180781 24038085 8413306 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
CXCL8 NFKB2 23180781 8413306 physical association electrophoretic mobility supershift assay InnateDB
CXCL8 TRIP6 15489293 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 NR3C1 15489293 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 RPS3 18045535 21399639 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 ELAVL1 15514971 18650551 19591856 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 TIAL1 15514971 23180781 physical association anti tag coimmunoprecipitation InnateDB
KHSRP CXCL8 15514971 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 CXCL8 1988949 2184886 23180781 8195702 physical association cross-linking study,nuclear magnetic resonance,x-ray crystallography InnateDB
CXCL8 CXCR1 10368283 12628493 1840701 23180781 8245475 8662882 8702798 9485196 physical association nuclear magnetic resonance,competition binding,saturation binding InnateDB
A2M CXCL8 23180781 9029135 physical association comigration in non denaturing gel electrophoresis,solid phase assay InnateDB
ELANE CXCL8 23180781 9029135 protein cleavage protease assay InnateDB
CXCL8 PIGR 11509627 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 PF4 12586630 23180781 physical association nuclear magnetic resonance,surface plasmon resonance InnateDB
CXCL8 MMP8 17375198 23180781 protein cleavage protease assay InnateDB
CXCL8 MMP1 17375198 18660381 23180781 protein cleavage protease assay InnateDB
CXCL8 MMP9 17375198 18660381 23180781 protein cleavage protease assay InnateDB
CXCL8 MMP13 17375198 23180781 protein cleavage protease assay InnateDB
CXCL8 CTNNB1 19173296 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 SDC1 12902511 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 ACKR1 15720550 23180781 7592830 8132497 9195930 physical association competition binding,saturation binding InnateDB
CXCL8 GNAI2 23180781 8662698 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 IRF3 17035306 18198374 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
CXCL8 CXCL5 11509627 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 CXCL2 11509627 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 HNRNPD 18650551 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 EGR1 18988806 19837667 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 EHMT1 21131967 23180781 physical association anti tag coimmunoprecipitation InnateDB
MMP12 CXCL8 18660381 23180781 protein cleavage protease assay InnateDB
CXCL8 CREB1 23180781 24038085 physical association anti tag coimmunoprecipitation InnateDB
BRD4 CXCL8 23180781 24761865 physical association anti tag coimmunoprecipitation InnateDB
KLF6 CXCL8 23180781 24634218 physical association anti tag coimmunoprecipitation InnateDB
BCL3 CXCL8 23180781 25089799 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR CXCL8 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
CEBPB CXCL8 11120852 15085176 15688424 16818736 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
DDIT3 CXCL8 18772138 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOS CXCL8 12218154 16818736 18971253 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CXCL8 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
JUN CXCL8 11120852 12218154 12643600 12716652 14670967 16701870 18684922 19132242 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
NFKB1 CXCL8 10477716 10506755 10530453 11120852 11297551 11342414 11512674 11564889 11953364 12058956 12218154 12485925 12643600 12707271 12716652 14631383 14670967 15289496 15350531 15387324 15517885 15688424 15950427 15958549 16004996 16105834 16701870 16764699 16803583 17040605 17041011 17045242 17917246 18074095 18281166 18996370 19376732 19732956 19786024 19837667 22340043 7876168 8413215 8878392 9698090 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
YBX1 CXCL8 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA CXCL8 10477716 10506755 10530453 11120852 11297551 11342414 11564889 11953364 12058956 12218154 12485925 12643600 12707271 12716652 14631383 14670967 15289496 15350531 15387324 15517885 15688424 15950427 15958549 16004996 16105834 16455661 16764699 16803583 16818736 17040605 17041011 17045242 17917246 18074095 18281166 18996370 19376732 19732956 19786024 19837667 19966855 22340043 22891766 7876168 8413215 8617886 8878392 9698090 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
FOXP3 CXCL8 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CXCL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CXCL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CXCL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CXCL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CXCL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CXCL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF4 CXCL8 16931790 trascriptional regulation,stimulation inferred by curator TFlink
DEK CXCL8 16829531 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CXCL8 15517885 19837667 trascriptional regulation,stimulation inferred by curator TFlink
ELF4 CXCL8 12438253 14625302 trascriptional regulation,stimulation inferred by curator TFlink
EP300 CXCL8 19966855 trascriptional regulation,stimulation inferred by curator TFlink
ERG CXCL8 19359602 22235125 trascriptional regulation,stimulation inferred by curator TFlink
KCNH2 CXCL8 19359602 22235125 trascriptional regulation,stimulation inferred by curator TFlink
ETS2 CXCL8 12438253 trascriptional regulation,stimulation inferred by curator TFlink
FOSB CXCL8 20826776 trascriptional regulation,stimulation inferred by curator TFlink
HDAC1 CXCL8 11564889 trascriptional regulation,stimulation inferred by curator TFlink
HDAC2 CXCL8 11564889 19411311 trascriptional regulation,stimulation inferred by curator TFlink
IKBKB CXCL8 12296854 trascriptional regulation,stimulation inferred by curator TFlink
ING4 CXCL8 17848618 20707719 trascriptional regulation,stimulation inferred by curator TFlink
NFE2L2 CXCL8 21925595 trascriptional regulation,stimulation inferred by curator TFlink
NFKBIA CXCL8 12296854 trascriptional regulation,stimulation inferred by curator TFlink
NR4A2 CXCL8 19732956 trascriptional regulation,stimulation inferred by curator TFlink
SFPQ CXCL8 24507715 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 CXCL8 17726017 trascriptional regulation,stimulation inferred by curator TFlink
STAT6 CXCL8 16004996 trascriptional regulation,stimulation inferred by curator TFlink
VDR CXCL8 24250750 9431991 trascriptional regulation,stimulation inferred by curator TFlink
XBP1 CXCL8 16931790 trascriptional regulation,stimulation inferred by curator TFlink
ZFP36 CXCL8 21593445 trascriptional regulation,stimulation inferred by curator TFlink
ZNF823 CXCL8 21593445 trascriptional regulation,stimulation inferred by curator TFlink
ZNF300 CXCL8 21777376 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink
ETV4 CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFKB2 CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARA CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink
REL CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink
TP53 CXCL8 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFBE3 CXCL8 18504431 rna interference,inhibition western blot,northern blot miRSponge
URS0000338542 CXCL8 21030878 rna interference,inhibition western blot miRSponge
URS00001EFBE3 CXCL8 18504431 20124483 25416803 mrna cleavage,inhibition array technology,western blot,northern blot TarBase
URS000029D9F1 CXCL8 21282569 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS0000237AF9 CXCL8 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 CXCL8 21030878 25416803 mrna cleavage,inhibition western blot TarBase
URS00001CC864 CXCL8 24498188 25416803 26314966 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000DDD35 CXCL8 24433094 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004DA9DB CXCL8 25416803 26304234 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS000027080C CXCL8 25416803 26199092 mrna cleavage,inhibition array technology,experimental interaction detection,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000041E949 CXCL8 25416803 26199092 mrna cleavage,inhibition array technology,experimental interaction detection,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00001A405B CXCL8 25416803 27542871 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000039E1E1 CXCL8 25416803 25950430 26265888 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000324096 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C85C7 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003D8730 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000024CEE0 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032BDF4 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C7662 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 CXCL8 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SGTA CXCL8 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CTSL CXCL8 12818188 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
EP300 CXCL8 25348397 N/A physical interaction ComPPI
BAG6 CXCL8 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PF4 CXCL8 12586630 14525934 15531763 24234451 25348397 28381538 N/A experimental interaction detection,filter binding,surface plasmon resonance,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
CCL5 CXCL8 25348397 N/A physical interaction ComPPI
WASF1 CXCL8 14525934 16862120 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CXCR2 CXCL8 14525934 22904195 23597562 24234451 25348397 8626516 8702798 9464567 physical association affinity chromatography technology,experimental interaction detection,scintillation proximity assay,surface plasmon resonance,physical interaction,biochemical,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
CCL4 CXCL8 14525934 25348397 27898060 8077676 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CCL8 CXCL8 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
SDC1 CXCL8 12902511 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CXCL8 MMP9 11023497 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CXCL8 IL12A 14525934 16862120 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CXCL8 GNAI2 14525934 25348397 8662698 N/A experimental interaction detection,in vivo ComPPI,HPRD
CXCL8 CXCR1 14525934 1840701 25348397 N/A affinity chromatography technology,experimental interaction detection,x-ray crystallography,physical interaction,biochemical,in vitro,in vivo ComPPI,HPRD
CXCL8 ARFGAP3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CXCL8 POMGNT1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CXCL8 ACKR1 14525934 17416748 25348397 9921412 N/A affinity chromatography technology,experimental interaction detection,physical interaction,biochemical ComPPI,HPRD
CXCL8 TNFAIP6 24234451 24501198 25348397 N/A surface plasmon resonance,enzyme linked immunosorbent assay ComPPI,IntAct
CXCL8 CCL2 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL8 CXCL8 10368283 10707023 14525934 1988949 2184886 2681204 9141135 N/A experimental interaction detection HPRD
CXCL8 TAT 18226242 27898060 N/A N/A OmniPath
CXCL8 GNAI2 27898060 8662698 N/A N/A OmniPath
ELANE CXCL8 27898060 9029135 stimulant N/A OmniPath
ELAVL1 CXCL8 18650551 19591856 27898060 stimulant N/A OmniPath
MMP9 CXCL8 11023497 17375198 18660381 27898060 N/A N/A OmniPath
TIAL1 CXCL8 15514971 27898060 N/A N/A OmniPath
CXCL8 HNRNPD 18650551 27898060 N/A N/A OmniPath
NFE2L2 CXCL8 16220540 27898060 N/A N/A OmniPath
RELA CXCL8 24634218 27898060 stimulant N/A OmniPath
EP300 CXCL8 11940655 15286281 27898060 stimulant N/A OmniPath
CXCL8 SDC2 14527339 27898060 N/A N/A OmniPath
CXCL8 SDC1 12902511 27898060 N/A N/A OmniPath
PF4 CXCL8 12586630 15531763 27898060 inhibition N/A OmniPath
KHSRP CXCL8 15514971 27898060 N/A N/A OmniPath
MMP13 CXCL8 17375198 27898060 N/A N/A OmniPath
MMP1 CXCL8 17375198 18660381 27898060 N/A N/A OmniPath
MMP8 CXCL8 17375198 27898060 N/A N/A OmniPath
PIGR CXCL8 11509627 27898060 N/A N/A OmniPath
CXCL8 A2M 27898060 9029135 N/A N/A OmniPath
CXCL8 CXCR2 10188995 10206993 10216072 11350788 12628493 1379593 15282370 15946947 19190236 22904195 23597562 24218476 27898060 7559482 7592830 8245475 8550564 8626516 8662882 8702798 8940121 9126332 9195914 9464567 9485196 9553055 9725262 stimulant N/A OmniPath
CXCR2 CXCL8 10206993 10216072 12628493 19190236 22904195 23597562 27898060 7559482 7592830 8245475 8550564 8626516 8662882 8702798 9126332 9195914 9464567 9485196 9553055 9725262 N/A N/A OmniPath
CXCL8 CXCR1 10188995 10206993 10368283 11350788 12628493 1379593 15282370 15946947 1840701 24218476 27898060 8245475 8550564 8662882 8702798 8940121 9195914 9485196 9553055 9725262 stimulant N/A OmniPath
CXCL8 ACKR1 10206993 15720550 17416748 24218476 27898060 7592830 8132497 8558064 9195930 9921412 N/A N/A OmniPath

Visualization










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