Gene Information gene info

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GENE：CRX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CRX
FullNmae cone-rod homeobox
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2383
EnsembleID ENSG00000105392
Uniprot O43186

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CRX autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CRX GO:0000785,GO:0000785,GO:0000977,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0001216,GO:0001228,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0006355,GO:0006357,GO:0007399,GO:0007601,GO:0009887,GO:0016922,GO:0030154,GO:0043522,GO:0045944,GO:0045944,GO:0050896,GO:0061629,GO:0090575,GO:1990837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TLE5 CRX 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 CRX 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 CRX 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA CRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A CRX 12408971 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000365675 CRX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 CRX 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039A052 CRX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032835F CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037E170 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000AD002 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001A122A CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 CRX 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CRX NRL 25361965 interaction type N/A PTMCode2
NRL CRX 25361965 interaction type N/A PTMCode2
CRX PDC 25361965 interaction type N/A PTMCode2
PDC CRX 25361965 interaction type N/A PTMCode2
CRX ATXN7 25361965 interaction type N/A PTMCode2
ATXN7 CRX 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RBPMS CRX 25348397 N/A barcode fusion genetics two hybrid ComPPI
VPS37C CRX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LGALS3 CRX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STK16 CRX 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CFAP206 CRX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOXF2 CRX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX GCM2 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
CRX PSMB10 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX ROR2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX DELE1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX UBXN2B 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX QRICH1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX ATXN7 25348397 N/A two hybrid,physical interaction ComPPI
CRX NRL 10887186 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
CRX NR2E3 14525934 15689355 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
CRX IPO13 14525934 15143176 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CRX PDC 10866677 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CRX MDFI 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CRX M1AP 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
CRX EP300 10708567 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CRX CREBBP 10708567 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CRX RAX2 14525934 15028672 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
CRX BANF1 12215455 25348397 27898060 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
CRX KAT2A 25348397 N/A physical interaction ComPPI
CRX SP4 25348397 N/A physical interaction ComPPI
CRX SP1 25348397 N/A physical interaction ComPPI
CRX SP3 25348397 N/A physical interaction ComPPI
CRX PRKCI 25348397 N/A physical interaction ComPPI
CRX RBFOX1 25348397 N/A physical interaction ComPPI
CRX NPAS2 25348397 N/A physical interaction ComPPI
CRX PRKN 25348397 N/A physical interaction ComPPI
CRX PRKAB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX TLE5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX CCNC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX EIF5A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX EIF5AL1 25348397 N/A physical interaction ComPPI
CRX MLLT6 25348397 N/A physical interaction ComPPI
CRX SOX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX ATG12 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX SFI1 25348397 N/A physical interaction ComPPI
CRX ABI2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX SZT2 25348397 N/A physical interaction ComPPI
CRX PPP1R16B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX OSGIN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX NIP7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX C1ORF109 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX PID1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX GUCD1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX LONRF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX LARP4 25348397 N/A physical interaction ComPPI
CRX KLHL32 25348397 N/A physical interaction ComPPI
CRX C9ORF72 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX HGS 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX SMUG1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRX PSMF1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
CRX PSMA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SAE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX PRR35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX MENT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SPG21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX NTF4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX C19ORF25 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX BOD1L2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX C1ORF50 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX GYS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX PNMA6A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX TFG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SUFU 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX AASDHPPT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX TLX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX ZC3H10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SOX10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX MYOZ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX POGZ 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX NEIL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SMAP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX TBX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX CDKN2C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SEC14L4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX TNS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SOX14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SOX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX ZIC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX ATXN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX OR6B1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX IRX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX ATP6V0D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SUOX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX FOXH1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX HNF1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX UBXN7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRX SMAD3 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
CA8 CRX 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
ARIH2 CRX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SP1 CRX 15781457 27898060 stimulant N/A OmniPath
SP4 CRX 15781457 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B96E2 CRX 27087310 direct interaction,inhibition N/A NPInter

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