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GENE：LAMP3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LAMP3
FullNmae lysosomal associated membrane protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14582
EnsembleID ENSG00000078081
Uniprot Q9UQV4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LAMP3 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
LAMP3 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
LAMP3 autophagy 24434718 Lysosome-associated membrane protein 3 (LAMP3) is a member of the LAMP-family of proteins, which are involved in the process of autophagy. retulator signature
LAMP3 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
LAMP3 GO:0002250,GO:0005765,GO:0005769,GO:0005886,GO:0005886,GO:0009986,GO:0010506,GO:0010628,GO:0031901,GO:0031902,GO:0031982,GO:0035455,GO:0043154,GO:0043231,GO:0048471,GO:0072594,GO:0097233,GO:1901799,GO:1903900

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LAMP3 hsa:27074 path:hsa04142 Lysosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 LAMP3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 LAMP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LAMP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LAMP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LAMP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LAMP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LAMP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LAMP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 LAMP3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001EFEC1 LAMP3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB LAMP3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA LAMP3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD LAMP3 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAD2L2 LAMP3 25348397 N/A physical interaction ComPPI
MARCHF5 LAMP3 25348397 N/A physical interaction ComPPI
MAPK8 LAMP3 25348397 N/A physical interaction ComPPI
JAK1 LAMP3 25348397 N/A physical interaction ComPPI
RAB3B LAMP3 25348397 N/A physical interaction ComPPI
CDC6 LAMP3 25348397 N/A physical interaction ComPPI
HUS1 LAMP3 25348397 N/A physical interaction ComPPI
RABGGTA LAMP3 25348397 N/A physical interaction ComPPI
SEC14L1 LAMP3 25348397 N/A physical interaction ComPPI
ARFGEF1 LAMP3 25348397 N/A physical interaction ComPPI
RAB9A LAMP3 23386062 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
PDK1 LAMP3 25348397 N/A physical interaction ComPPI
NISCH LAMP3 23386062 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
MAP2K7 LAMP3 25348397 N/A physical interaction ComPPI
RIF1 LAMP3 25348397 N/A physical interaction ComPPI
XRCC3 LAMP3 25348397 N/A physical interaction ComPPI
NEK6 LAMP3 25348397 N/A physical interaction ComPPI
NEK7 LAMP3 25348397 N/A physical interaction ComPPI
HEATR1 LAMP3 25348397 N/A physical interaction ComPPI
TUBB3 LAMP3 25348397 N/A physical interaction ComPPI
UGDH LAMP3 25348397 N/A physical interaction ComPPI
KNTC1 LAMP3 25348397 N/A physical interaction ComPPI
FLOT2 LAMP3 24234451 24809731 25348397 colocalization fluorescence microscopy ComPPI,IntAct
GLS LAMP3 25348397 N/A physical interaction ComPPI
PDS5A LAMP3 25348397 N/A physical interaction ComPPI
TUBB2A LAMP3 25348397 N/A physical interaction ComPPI
ARFGEF2 LAMP3 25348397 N/A physical interaction ComPPI
TUBB2B LAMP3 25348397 N/A physical interaction ComPPI
LTN1 LAMP3 25348397 N/A physical interaction ComPPI
RNF213 LAMP3 25348397 N/A physical interaction ComPPI
MYADM LAMP3 25348397 N/A physical interaction ComPPI
UTP15 LAMP3 25348397 N/A physical interaction ComPPI
HBS1L LAMP3 25348397 N/A physical interaction ComPPI
ZRANB3 LAMP3 25348397 N/A physical interaction ComPPI
ATL3 LAMP3 25348397 N/A physical interaction ComPPI

Visualization










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