Gene Information gene info

GENE:PRKAA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRKAA1
FullNmae protein kinase AMP-activated catalytic subunit alpha 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9376
EnsembleID ENSG00000132356
Uniprot Q13131

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRKAA1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRKAA1 autophagy 34612140 Our results indicate that the enhanced autophagy activity in EC was controlled by the energy-sensing PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1). retulator signature
PRKAA1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PRKAA1 GO:0000785,GO:0001666,GO:0003682,GO:0004672,GO:0004674,GO:0004674,GO:0004679,GO:0004679,GO:0004679,GO:0004691,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006006,GO:0006338,GO:0006468,GO:0006468,GO:0006633,GO:0006695,GO:0006914,GO:0007165,GO:0008284,GO:0008610,GO:0009411,GO:0009631,GO:0010332,GO:0010508,GO:0010508,GO:0010508,GO:0010628,GO:0010629,GO:0014823,GO:0015721,GO:0016055,GO:0016324,GO:0016607,GO:0019395,GO:0030424,GO:0030425,GO:0031000,GO:0031588,GO:0031588,GO:0031588,GO:0031588,GO:0031669,GO:0031669,GO:0032007,GO:0032007,GO:0033135,GO:0034599,GO:0035556,GO:0038183,GO:0042149,GO:0042149,GO:0042593,GO:0042752,GO:0043025,GO:0043066,GO:0043627,GO:0045542,GO:0045821,GO:0045893,GO:0046318,GO:0046627,GO:0046872,GO:0047322,GO:0048156,GO:0048511,GO:0048643,GO:0050321,GO:0050405,GO:0050995,GO:0055089,GO:0060627,GO:0061744,GO:0061762,GO:0061762,GO:0061762,GO:0062028,GO:0070050,GO:0070301,GO:0070507,GO:0071277,GO:0071333,GO:0071361,GO:0071380,GO:0071417,GO:0071456,GO:0071466,GO:0097009,GO:0097009,GO:0106310,GO:0120188,GO:0140823,GO:1903109,GO:1903829,GO:1903944,GO:1903955,GO:1904179,GO:1904262,GO:1904428,GO:1905691,GO:1990044,GO:2000758

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRKAA1 hsa:5562 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04140 Autophagy - animal - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04530 Tight junction - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04710 Circadian rhythm - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04714 Thermogenesis - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04922 Glucagon signaling pathway - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04931 Insulin resistance - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
PRKAA1 hsa:5562 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TLE5 PRKAA1 23180781 25416956 physical association two hybrid InnateDB
PRKAA1 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ABI1 PRKAA1 20005715 interaction type N/A PSP,SignaLink
PRKAB1 PRKAA1 20005715 interaction type N/A PSP
PRKAB2 PRKAA1 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
E2F4 PRKAA1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PRKAA1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 PRKAA1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PRKAA1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MITF PRKAA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PRKAA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 PRKAA1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00002C0FCB PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000065D58 PRKAA1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000013DD8 PRKAA1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001DE669 PRKAA1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003ABC4 PRKAA1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A PRKAA1 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1B PRKAA1 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005C1F22 PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027464B PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B0E50 PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000412AC7 PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000759EB8 PRKAA1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 PRKAA1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 PRKAA1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B PRKAA1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 PRKAA1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A PRKAA1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 PRKAA1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PRKAA1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PRKAA1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PRKAA1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 PRKAA1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 PRKAA1 25416803 27199118 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001E3523 PRKAA1 25416803 27497953 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 PRKAB1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKAA1 ATG9A 22135298 phosphorylation N/A PhosphoSite
PRKAA1 NET1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 PRKAA1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 SNX17 22135298 phosphorylation N/A PhosphoSite
PRKAA1 HDAC5 22135298 phosphorylation N/A PhosphoSite
PRKAA1 GAPDH 22135298 phosphorylation N/A PhosphoSite
PRKAA1 NOS3 22135298 phosphorylation N/A PhosphoSite
PRKAA1 VASP 22135298 phosphorylation N/A PhosphoSite
PRKAA1 ACACA 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKAA1 PPP1R3C 22135298 phosphorylation N/A PhosphoSite
PRKAA1 YAP1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 RACK1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 EPM2A 22135298 phosphorylation N/A PhosphoSite
PRKAA1 RRN3 22135298 phosphorylation N/A PhosphoSite
PRKAA1 KLC2 22135298 phosphorylation N/A PhosphoSite
PRKAA1 KPNA2 22135298 phosphorylation N/A PhosphoSite
PRKAA1 EEF2K 22135298 phosphorylation N/A PhosphoSite
PRKAA1 PFKFB2 22135298 phosphorylation N/A PhosphoSite
PRKAA1 CFTR 22135298 phosphorylation N/A PhosphoSite
PRKAA1 FOXO3 22135298 phosphorylation N/A PhosphoSite
PRKAA1 CDKN1B 22135298 phosphorylation N/A PhosphoSite
PRKAA1 GLI1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 DDIT3 22135298 phosphorylation N/A PhosphoSite
PRKAA1 PPP1R12C 22135298 phosphorylation N/A PhosphoSite
PRKAA1 PAQR3 22135298 phosphorylation N/A PhosphoSite
PRKAA1 TP53 22135298 phosphorylation N/A PhosphoSite
PRKAA1 EGFR 22135298 phosphorylation N/A PhosphoSite
PRKAA1 GBF1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 TNNI3 22135298 phosphorylation N/A PhosphoSite
PRKAA1 RPTOR 22135298 phosphorylation N/A PhosphoSite
PRKAA1 SLC12A1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 PIAS1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 PPP2R5C 22135298 phosphorylation N/A PhosphoSite
PRKAA1 HNF4A 22135298 phosphorylation N/A PhosphoSite
PRKAA1 CSNK1E 22135298 phosphorylation N/A PhosphoSite
PRKAA1 ERBB2 22135298 phosphorylation N/A PhosphoSite
PRKAA1 USP10 22135298 phosphorylation N/A PhosphoSite
PRKAA1 FANCA 22135298 phosphorylation N/A PhosphoSite
PRKAA1 BECN1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 ULK1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 ZNF692 22135298 phosphorylation N/A PhosphoSite
PRKAA1 TP73 22135298 phosphorylation N/A PhosphoSite
PRKAA1 LIPE 22135298 phosphorylation N/A PhosphoSite
PRKAA1 GFPT1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 EP300 22135298 phosphorylation N/A PhosphoSite
PRKAA1 TBC1D1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 KLC1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 PFKFB3 22135298 phosphorylation N/A PhosphoSite
PRKAA1 CGN 22135298 phosphorylation N/A PhosphoSite
PRKAA1 SIRT2 22135298 phosphorylation N/A PhosphoSite
PRKAA1 POU2F1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 CTBP1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 CTTN 22135298 phosphorylation N/A PhosphoSite
PRKAA1 BRAF 22135298 phosphorylation N/A PhosphoSite
PRKAA1 FOXO1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 SYK 22135298 phosphorylation N/A PhosphoSite
PRKAA1 ACACB 22135298 phosphorylation N/A PhosphoSite
CAMKK1 PRKAA1 22135298 phosphorylation N/A PhosphoSite
BRSK2 PRKAA1 22135298 phosphorylation N/A PhosphoSite
STK11 PRKAA1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
GSK3B PRKAA1 22135298 phosphorylation N/A PhosphoSite
CAMK2B PRKAA1 22135298 phosphorylation N/A PhosphoSite
MAP3K11 PRKAA1 22135298 phosphorylation N/A PhosphoSite
CAMKK2 PRKAA1 22135298 phosphorylation N/A PhosphoSite
PRKCA PRKAA1 22135298 phosphorylation N/A PhosphoSite
PRKCB PRKAA1 22135298 phosphorylation N/A PhosphoSite
AKT1 PRKAA1 22135298 phosphorylation N/A PhosphoSite
PRKAG1 PRKAA1 25361965 interaction type N/A PTMCode2
PRKAA1 PRKAG1 25361965 interaction type N/A PTMCode2
ACACA PRKAA1 25361965 interaction type N/A PTMCode2
PRKAA1 STK11 25361965 interaction type N/A PTMCode2
PRKAB1 PRKAA1 25361965 interaction type N/A PTMCode2
PRKAA1 PRKAA2 25361965 interaction type N/A PTMCode2
PRKAA2 PRKAA1 25361965 interaction type N/A PTMCode2
PRKAG3 PRKAA1 25361965 interaction type N/A PTMCode2
PRKAA1 PRKAG3 25361965 interaction type N/A PTMCode2
CAB39 PRKAA1 25361965 interaction type N/A PTMCode2
PRKAA1 CAB39 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RBPMS PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GOLGA2 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZBED1 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA2 PRKAA1 20562859 20801214 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BHLHE40 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDX4 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FXR2 PRKAA1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PNMA5 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VCP PRKAA1 25348397 N/A physical interaction ComPPI
MCM2 PRKAA1 25348397 N/A physical interaction ComPPI
KRT40 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSP90AB1 PRKAA1 22939624 23455922 24234451 25348397 association,physical association physical interaction,tandem affinity purification,luminescence based mammalian interactome mapping ComPPI,IntAct
RFX6 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PHC2 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIK2 PRKAA1 25348397 N/A physical interaction ComPPI
VPS37B PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXNIP PRKAA1 25348397 N/A physical interaction ComPPI
NOTCH1 PRKAA1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SND1 PRKAA1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBXN11 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EP300 PRKAA1 25348397 N/A physical interaction ComPPI
SNRK PRKAA1 25348397 N/A physical interaction ComPPI
GATA1 PRKAA1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CTBP1 PRKAA1 25348397 N/A physical interaction ComPPI
GLI1 PRKAA1 25348397 N/A physical interaction ComPPI
EIF5B PRKAA1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD11 PRKAA1 25348397 N/A physical interaction ComPPI
PPARGC1A PRKAA1 25348397 N/A physical interaction ComPPI
YWHAZ PRKAA1 25348397 N/A physical interaction ComPPI
PPM1A PRKAA1 25348397 N/A physical interaction ComPPI
PFKFB2 PRKAA1 12853467 1322130 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKAA1 CFTR 10862786 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKAA1 PRKAB2 14525934 16306228 20562859 21988832 22363791 23455922 24234451 25348397 25416956 25852190 8626596 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PRKAA1 EEF2K 11171059 11500364 14525934 14709557 15024086 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKAA1 CAB39 14525934 25348397 8910387 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKAA1 TOMM34 11913976 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PRKAA1 PRKAG3 14525934 25348397 8626596 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PRKAA1 PRKAB1 14525934 16306228 18480843 20562859 22363791 23455922 24234451 25348397 25852190 8626596 8663446 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
PRKAA1 PRKAG1 14525934 16306228 20562859 22363791 23455922 24234451 25348397 25416956 25852190 8663446 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vitro,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
PRKAA1 MTOR 14525934 14970221 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRKAA1 RAF1 11971957 14525934 25348397 9091312 9710607 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKAA1 TSC2 25348397 N/A physical interaction ComPPI
PRKAA1 FNIP1 25348397 N/A physical interaction ComPPI
PRKAA1 SUPT16H 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 PA2G4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 G3BP1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 PARP1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 FMR1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 RPL35 25348397 N/A physical interaction ComPPI
PRKAA1 PRKAG2 20562859 23455922 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PRKAA1 ULK1 20562859 21072212 24234451 25348397 25686248 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 HSP90AA1 16306228 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PRKAA1 HSP90AA2P 25348397 N/A physical interaction ComPPI
PRKAA1 HSPA4 25348397 N/A physical interaction ComPPI
PRKAA1 TUBA1A 25348397 N/A physical interaction ComPPI
PRKAA1 CDC37 16306228 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PRKAA1 YWHAE 25348397 N/A physical interaction ComPPI
PRKAA1 SIK1 25348397 N/A physical interaction ComPPI
PRKAA1 PPP2R1B 25348397 N/A physical interaction ComPPI
PRKAA1 PPP2CA 25348397 N/A physical interaction ComPPI
PRKAA1 USP2 25348397 N/A physical interaction ComPPI
PRKAA1 NUAK1 25348397 N/A physical interaction ComPPI
PRKAA1 NUAK2 25348397 N/A physical interaction ComPPI
PRKAA1 BRSK1 25348397 N/A physical interaction ComPPI
PRKAA1 BRSK2 25348397 N/A physical interaction ComPPI
PRKAA1 MARK1 25348397 N/A physical interaction ComPPI
PRKAA1 MARK2 25348397 N/A physical interaction ComPPI
PRKAA1 MARK3 25348397 N/A physical interaction ComPPI
PRKAA1 MARK4 25348397 N/A physical interaction ComPPI
PRKAA1 ELAVL1 25348397 N/A physical interaction ComPPI
PRKAA1 CRBN 25348397 N/A physical interaction ComPPI
PRKAA1 EPM2A 25348397 N/A physical interaction ComPPI
PRKAA1 RPTOR 25348397 N/A physical interaction ComPPI
PRKAA1 HDAC5 25348397 N/A physical interaction ComPPI
PRKAA1 CRTC2 25348397 N/A physical interaction ComPPI
PRKAA1 MAP3K7 25348397 N/A physical interaction ComPPI
PRKAA1 ABI1 20368287 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PRKAA1 CPE 20368287 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PRKAA1 MORC4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKAA1 PLEKHA4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKAA1 SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
PRKAA1 MDM4 25348397 N/A physical interaction ComPPI
PRKAA1 ACACA 11052978 14525934 23455922 24234451 25348397 2900138 7907095 association experimental interaction detection,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
PRKAA1 FKBP5 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PRKAA1 EGFR 25348397 N/A physical interaction ComPPI
PRKAA1 PPARG 25348397 N/A physical interaction ComPPI
PRKAA1 STK11 22575644 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
PRKAA1 TLE5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 VPS52 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 TRIP6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 ABI2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 IKZF3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 FSBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 RAD54B 25348397 N/A physical interaction ComPPI
PRKAA1 ROPN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 THAP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 HOMEZ 25348397 N/A physical interaction ComPPI
PRKAA1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 TSC22D4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 L3MBTL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 RIMBP3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 SSX2IP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 INO80E 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA1 CCDC8 25348397 N/A physical interaction ComPPI
PRKAA1 INSR 25348397 N/A physical interaction ComPPI
PRKAA1 PPM1F 20801214 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 PPM1E 25348397 N/A physical interaction ComPPI
PRKAA1 CAMKK1 25348397 N/A physical interaction ComPPI
PRKAA1 MAST3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 SUN2 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 TRAK2 25348397 N/A physical interaction ComPPI
PRKAA1 MCL1 25348397 N/A physical interaction ComPPI
PRKAA1 DCLRE1C 25348397 N/A physical interaction ComPPI
PRKAA1 NUP50 25348397 N/A physical interaction ComPPI
PRKAA1 NTRK1 25348397 N/A physical interaction ComPPI
PRKAA1 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PRKAA1 DVL2 25348397 N/A physical interaction ComPPI
PRKAA1 ASPM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 USP10 25348397 N/A physical interaction ComPPI
PRKAA1 STIM2 25348397 N/A physical interaction ComPPI
PRKAA1 PHKG2 25348397 N/A physical interaction ComPPI
PRKAA1 CUTA 25348397 N/A physical interaction ComPPI
PRKAA1 CCKBR 25348397 N/A physical interaction ComPPI
PRKAA1 FANCG 25348397 N/A physical interaction ComPPI
PRKAA1 FANCA 25348397 N/A physical interaction ComPPI
PRKAA1 PASK 25348397 N/A physical interaction ComPPI
PRKAA1 MYL9 17486097 24234451 25348397 phosphorylation reaction phosphorylation reaction,protein kinase assay ComPPI,IntAct
PRKAA1 YAP1 24234451 25348397 25751139 25751140 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PRKAA1 SLC25A5 16306228 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PRKAA1 HSPA5 16306228 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PRKAA1 ULK2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRKAA1 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRKAA1 KSR2 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PRKAA1 ANG 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
SIK3 PRKAA1 25348397 N/A physical interaction ComPPI
DDA1 PRKAA1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA1 GRIK2 14525934 8094892 8163463 N/A experimental interaction detection HPRD
PRKAA1 PRKAA1 20562859 24234451 physical association anti tag coimmunoprecipitation IntAct
PRKAA1 FLCN 19914239 27898060 N/A N/A OmniPath
PRKAA1 RC3H1 26496200 27898060 N/A N/A OmniPath
PRKACA PRKAA1 15980064 19376078 27898060 8910387 inhibition N/A OmniPath
PRKAA1 TNNI3 22456184 22493448 24657721 27898060 N/A N/A OmniPath
PRKAA1 SYN1 10880969 27898060 inhibition N/A OmniPath
CAMK2B PRKAA1 15980064 27898060 stimulant N/A OmniPath
PRKAA1 NOS3 10376603 11029403 11319202 11402048 11425855 11978735 12446767 12522122 12644590 12791703 16043647 16338973 16873402 16946136 17572401 18303014 23768697 24379783 26132171 27898060 inhibition,stimulant N/A OmniPath
PRKAA1 SIRT2 24446434 27898060 N/A N/A OmniPath
PRKAA1 SREBF1 21459323 21892142 27898060 inhibition N/A OmniPath
PRKAA1 RB1 19217427 27898060 inhibition N/A OmniPath
PRKAA1 FOXO4 17900900 27898060 stimulant N/A OmniPath
PRKAA1 CRTC2 21892142 27898060 inhibition N/A OmniPath
PRKAA1 FOXO3 17711846 22474372 27898060 stimulant N/A OmniPath
STK11 PRKAA1 12391032 12944390 14511394 14532170 14614828 14985505 15327994 15980064 16041368 16115917 16600998 16912160 17287464 17728241 18056705 18617528 18693249 19036825 19366811 19414597 19884317 20135346 20479254 20616029 20656472 20685962 20801214 20938636 21399626 21474997 21673972 21680840 24289924 24652283 25683918 25696921 25792737 25874865 26068970 26247630 27898060 stimulant N/A OmniPath
PRKAA1 CDKN1B 17053782 18593906 19118035 27898060 N/A N/A OmniPath
PRKAA1 PRKAB1 16306228 17728241 18480843 20562859 21232561 22939629 23455922 25852190 26344197 27898060 8621713 8626596 8663446 stimulant N/A OmniPath
PRKAA1 CSNK1E 17525164 27898060 N/A N/A OmniPath
PRKAA1 PPARGC1A 17609368 27898060 stimulant N/A OmniPath
ULK1 PRKAA1 20562859 21460634 25686248 27898060 inhibition N/A OmniPath
PRKAA1 ULK1 20562859 21460634 25686248 27898060 stimulant N/A OmniPath
PRKAA1 FOXO1 17900900 27898060 stimulant N/A OmniPath
PRKAA1 ATG9A 25266655 27898060 N/A N/A OmniPath
PRKAA1 ACACA 11052978 14985505 15107497 15371448 15383373 15967841 16407220 16434556 17116771 17137347 17237771 17244528 17255104 17272808 17276402 18195011 18212344 18303014 18431490 18474592 18480843 18482975 18669648 18707149 18715874 18767875 18854318 19061860 19176702 19651622 19958286 20068231 20166139 20489196 21062936 21918180 21931634 22137581 22517326 22561688 23325788 23418352 23455922 23612973 23909401 24247980 24702155 24959379 25065674 25679763 25762623 26143491 26456332 26506235 27898060 2900138 7907095 inhibition N/A OmniPath
PRKAA1 KPNA2 15342649 17919121 27898060 stimulant N/A OmniPath
PRKAA1 TBC1D1 17995453 27898060 inhibition N/A OmniPath
PRKAA1 TP53 10606744 10733583 11883897 15355354 15542844 15866171 18246126 21386980 27898060 stimulant N/A OmniPath
PRKAA1 CTBP1 23291169 27898060 inhibition N/A OmniPath
CAMKK2 PRKAA1 21918180 27898060 stimulant N/A OmniPath
PRKAA1 RAF1 11971957 19007248 19651622 20068231 20166139 27898060 9091312 9710607 inhibition,stimulant N/A OmniPath
PRKAA1 HDAC4 21565617 27898060 inhibition N/A OmniPath
PRKAA1 CRY1 21892142 27898060 inhibition N/A OmniPath
PRKAA1 EP300 11020388 11518699 12379484 15006641 21940946 22465714 27898060 inhibition N/A OmniPath
PPP2CA PRKAA1 16306228 22065577 27898060 8652652 N/A N/A OmniPath
PRKAA1 NR2C2 21478464 27898060 inhibition N/A OmniPath
PRKAA1 TP73 24874608 27898060 N/A N/A OmniPath
PRKAA1 RPTOR 18439900 20169205 20227367 20354225 21460630 21460634 21900751 23142078 23928304 24247720 25728766 26212320 26348909 26391395 27898060 inhibition N/A OmniPath
PRKAA1 POU2F1 1684878 27898060 9368058 inhibition N/A OmniPath
PRKAA1 MAPT 16606369 18949077 27898060 N/A N/A OmniPath
CAMKK1 PRKAA1 21918180 27898060 stimulant N/A OmniPath
PRKAA1 PFKFB3 12065600 27898060 stimulant N/A OmniPath
PRKAA1 SNAI1 19923321 27898060 stimulant N/A OmniPath
PRKAA1 KLC1 20074060 21099273 27898060 N/A N/A OmniPath
PRKAA1 CFTR 10862786 11053017 14602047 15657296 16887929 1716180 19095655 19328185 19419994 20861072 20952391 21455600 23060444 24727471 25330774 25867080 26079370 27898060 9385646 N/A N/A OmniPath
PRKAA1 HDAC5 21892142 27898060 inhibition N/A OmniPath
PRKAA1 PFKFB2 11069105 12853467 1322130 17924679 18669648 18767875 19413330 19651622 20068231 27898060 stimulant N/A OmniPath
PRKAA1 HNF4A 12740371 16351573 21598922 27898060 inhibition N/A OmniPath
PRKAA1 HDAC7 21892142 27898060 inhibition N/A OmniPath
PRKAA1 EEF2K 11171059 11500364 14709557 15024086 22669845 27898060 stimulant N/A OmniPath
PRKAA1 ACACB 12068056 12413941 12488245 16051629 27898060 inhibition N/A OmniPath
PRKAA1 GBF1 18063581 27898060 inhibition N/A OmniPath
PRKAA1 LIPE 27898060 9636039 inhibition N/A OmniPath
PRKAA1 KLC2 21725060 27898060 stimulant N/A OmniPath
PRKAA1 MLXIPL 11724780 21892142 27898060 inhibition N/A OmniPath
PRKAA1 RRN3 19815529 27898060 inhibition N/A OmniPath
PRKAA1 GRIK2 27898060 8094892 8163463 N/A N/A OmniPath
PPP2CB PRKAA1 27898060 8652652 N/A N/A OmniPath
BRSK2 PRKAA1 21918180 27898060 stimulant N/A OmniPath
PRKAA1 MFF 26816379 27898060 stimulant N/A OmniPath
PRKAA1 CRTC1 21331044 27898060 inhibition N/A OmniPath
PRKAA1 ZNF692 17097062 27898060 inhibition N/A OmniPath
PRKAA1 GFPT1 17941647 19170765 27898060 inhibition,stimulant N/A OmniPath
PRKAA1 SLC12A1 21321328 27898060 N/A N/A OmniPath
PRKAA1 CGN 26083411 27898060 N/A N/A OmniPath
PRKAA1 EPM2A 21728993 27898060 N/A N/A OmniPath
PRKAA1 PPP1R3C 19171932 27898060 N/A N/A OmniPath

Visualization