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GENE：RIMS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RIMS2
FullNmae regulating synaptic membrane exocytosis 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17283
EnsembleID ENSG00000176406
Uniprot Q9UQ26

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RIMS2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RIMS2 GO:0005515,GO:0006886,GO:0007188,GO:0017156,GO:0017157,GO:0030073,GO:0030154,GO:0031267,GO:0042391,GO:0042391,GO:0042734,GO:0042995,GO:0044325,GO:0044325,GO:0046872,GO:0048167,GO:0048786,GO:0048788,GO:0048791,GO:0048791,GO:0050806,GO:0061669,GO:0070062,GO:0097151,GO:1903861,GO:2000300,GO:2000463

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RIMS2 hsa:9699 path:hsa04911 Insulin secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 RIMS2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RIMS2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RIMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 RIMS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD231 RIMS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 RIMS2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RABAC1 RIMS2 10707984 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
LYN RIMS2 25348397 N/A physical interaction ComPPI
RPH3AL RIMS2 10707984 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
RIMS2 RAB3B 12578829 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RIMS2 YWHAH 12871946 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RIMS2 RAB27A 12578829 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RIMS2 ABCA1 14525934 16192289 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
RIMS2 MYC 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RIMS2 FYN 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RIMS2 GRB2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RIMS2 NCK1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RIMS2 ESR2 21182203 24234451 25348397 association cosedimentation through density gradient ComPPI,IntAct
CACNA1S RIMS2 14525934 14660679 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD

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