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GENE：TP53INP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TP53INP2
FullNmae tumor protein p53 inducible nuclear protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16104
EnsembleID ENSG00000078804
Uniprot Q8IXH6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TP53INP2 autophagy 31810209 Tumor protein p53 inducible nuclear protein 2 (TP53INP2) is a key positive regulator of autophagy, and it has been shown to modulate adipocyte differentiation. retulator signature
TP53INP2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TP53INP2 GO:0000045,GO:0000045,GO:0001649,GO:0001894,GO:0005515,GO:0005634,GO:0005634,GO:0005776,GO:0005776,GO:0005829,GO:0006511,GO:0008104,GO:0016605,GO:0031410,GO:0043130,GO:0045893,GO:0045893,GO:1903828

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TP53INP2 hsa:58476 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAP1LC3A TP53INP2 19056683 23180781 physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid InnateDB
GABARAP TP53INP2 19056683 23180781 physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid InnateDB
GABARAPL2 TP53INP2 19056683 23180781 physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR TP53INP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 TP53INP2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 TP53INP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TP53INP2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TP53INP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002F3336 TP53INP2 23807165 25416803 mrna cleavage,inhibition array technology TarBase
URS0000330617 TP53INP2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F TP53INP2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000022B729 TP53INP2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 TP53INP2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D TP53INP2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 TP53INP2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 TP53INP2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GABARAPL2 TP53INP2 20010805 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAP1LC3A TP53INP2 25348397 N/A physical interaction ComPPI
TP53INP2 MAP1LC3A 19056683 27898060 stimulant N/A OmniPath
TP53INP2 GABARAPL2 19056683 20010805 27898060 stimulant N/A OmniPath

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