Gene Information gene info

GENE:USP13

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP13
FullNmae ubiquitin specific peptidase 13
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12611
EnsembleID ENSG00000058056
Uniprot Q92995

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP13 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP13 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP13 autophagy 39216303 USP13 promotes AML cell growth and autophagy by upregulating ATG5. retulator signature
USP13 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
USP13 GO:0004197,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0005829,GO:0006355,GO:0006914,GO:0008270,GO:0008283,GO:0010506,GO:0016579,GO:0030318,GO:0031625,GO:0035523,GO:0043130,GO:0044313,GO:0044389,GO:0050821,GO:0050821,GO:0051087,GO:0070536,GO:0070628,GO:1904288,GO:1904294,GO:1904378,GO:1990380

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR USP13 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TFAP2C USP13 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 USP13 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000006FDD4 USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000042E8CC USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 USP13 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B USP13 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 USP13 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D USP13 25416803 27869170 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
USP13 TRIM63 25361965 interaction type N/A PTMCode2
TRIM63 USP13 25361965 interaction type N/A PTMCode2
KCTD10 USP13 25361965 interaction type N/A PTMCode2
USP13 KCTD10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STAT1 USP13 25348397 N/A physical interaction ComPPI
UBL4A USP13 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VCP USP13 25348397 N/A physical interaction ComPPI
RAD21 USP13 25348397 N/A physical interaction ComPPI
LAPTM5 USP13 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SIAH2 USP13 21659512 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBC USP13 25348397 N/A physical interaction ComPPI
BAG6 USP13 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CACYBP USP13 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC1 USP13 25348397 N/A physical interaction ComPPI
RAD23A USP13 25348397 N/A physical interaction ComPPI
USP13 TRIM63 11927605 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
USP13 TRIM55 11927605 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
USP13 FNBP1L 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
USP13 MRPL20 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
USP13 DVL1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
USP13 MYO15A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
USP13 DVL1P1 25348397 N/A physical interaction ComPPI
USP13 CYLD 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 DLST 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 NEDD8 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 OGDH 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 UFD1 19615732 21571647 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
USP13 SMC1A 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 ATXN3 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
USP13 USP5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 SMC3 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 TCAF1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 FAF2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 KCTD3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 NPLOC4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 DIABLO 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 ITCH 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 KCTD10 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 PMS1 25348397 N/A physical interaction ComPPI
USP13 SKP2 25348397 N/A physical interaction ComPPI
USP13 THOC7 25348397 N/A physical interaction ComPPI
USP13 UBE3C 25348397 N/A physical interaction ComPPI
USP13 PTEN 24270891 25348397 26280536 26453058 27898060 N/A anti bait coimmunoprecipitation,physical interaction ComPPI,OmniPath
USP13 MOV10 25348397 N/A physical interaction ComPPI
USP13 AMFR 25348397 N/A physical interaction ComPPI
USP13 GET4 25348397 N/A physical interaction ComPPI
USP13 SCCPDH 25348397 N/A physical interaction ComPPI
USP13 RPP25 25348397 N/A physical interaction ComPPI
USP13 YTHDF2 25348397 N/A physical interaction ComPPI
USP13 SYNCRIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP13 ACLY 25348397 N/A physical interaction ComPPI
USP13 STING1 25348397 N/A physical interaction ComPPI
USP13 ZEB1 25348397 N/A physical interaction ComPPI
USP13 UIMC1 25348397 N/A physical interaction ComPPI
USP13 MDC1 25348397 N/A physical interaction ComPPI
USP13 L1RE1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
USP13 SPRR2D 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
USP13 DAZAP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FUNDC2 USP13 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct

Visualization