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GENE：ZBTB17

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZBTB17
FullNmae zinc finger and BTB domain containing 17
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12936
EnsembleID ENSG00000116809
Uniprot Q13105

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZBTB17 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ZBTB17 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZBTB17 GO:0000122,GO:0000978,GO:0000978,GO:0001046,GO:0001223,GO:0001227,GO:0001228,GO:0001228,GO:0001702,GO:0001817,GO:0002682,GO:0003700,GO:0005515,GO:0005654,GO:0005654,GO:0007398,GO:0008285,GO:0032991,GO:0032993,GO:0045786,GO:0045944,GO:0045944,GO:0046872,GO:0070314,GO:0140297

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ZBTB17 hsa:7709 path:hsa04110 Cell cycle - Homo sapiens (human)
ZBTB17 hsa:7709 path:hsa05200 Pathways in cancer - Homo sapiens (human)
ZBTB17 hsa:7709 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
ZBTB17 hsa:7709 path:hsa05222 Small cell lung cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYC ZBTB17 23180781 9312026 physical association two hybrid InnateDB
CCND1 ZBTB17 23180781 9312026 physical association electrophoretic mobility shift assay InnateDB
IRF8 ZBTB17 12904288 23180781 physical association two hybrid InnateDB
KLF5 ZBTB17 19419955 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDKN2A ZBTB17 19901969 23180781 physical association anti tag coimmunoprecipitation InnateDB
TP53 ZBTB17 19901969 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ZBTB17 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ZBTB17 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ZBTB17 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ZBTB17 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ZBTB17 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ZBTB17 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ZBTB17 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ZBTB17 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
MAX ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 MAX 25361965 interaction type N/A PTMCode2
ZBTB17 MYC 25361965 interaction type N/A PTMCode2
MYC ZBTB17 25361965 interaction type N/A PTMCode2
HCFC1 ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 HCFC1 25361965 interaction type N/A PTMCode2
GTF2I ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 GTF2I 25361965 interaction type N/A PTMCode2
TOPBP1 ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 TOPBP1 25361965 interaction type N/A PTMCode2
DNMT3A ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 DNMT3A 25361965 interaction type N/A PTMCode2
CDKN2A ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 CDKN2A 25361965 interaction type N/A PTMCode2
IRF8 ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 IRF8 25361965 interaction type N/A PTMCode2
GFI1 ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 GFI1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZBTB8A ZBTB17 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAGEA4 ZBTB17 14739298 24234451 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,confocal microscopy ComPPI,IntAct,OmniPath
HK2 ZBTB17 11068878 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
ITGB5 ZBTB17 12356872 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HSP90AB1 ZBTB17 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HCFC1 ZBTB17 12244100 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CREBBP ZBTB17 14525934 15752756 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
EP300 ZBTB17 12244100 12840021 14525934 24234451 25348397 27898060 physical association experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
IRF8 ZBTB17 12904288 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
GTF2I ZBTB17 12193603 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
CDKN2A ZBTB17 25348397 N/A physical interaction ComPPI
HSP90AA1 ZBTB17 25348397 N/A physical interaction ComPPI
MYC ZBTB17 14525934 16352593 18923429 24234451 25348397 26766587 9312026 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
KLF5 ZBTB17 25348397 N/A physical interaction ComPPI
YWHAQ ZBTB17 25348397 N/A physical interaction ComPPI
HUWE1 ZBTB17 25348397 N/A physical interaction ComPPI
DVL2 ZBTB17 25348397 N/A physical interaction ComPPI
YWHAH ZBTB17 15580267 24234451 25348397 27898060 association coimmunoprecipitation ComPPI,IntAct,OmniPath
DNMT3A ZBTB17 14525934 15616584 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ZBTB17 CDKN2B 11283613 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ZBTB17 DIS3 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZBTB17 MSX2 14525934 25348397 9256341 N/A experimental interaction detection,in vitro ComPPI,HPRD
ZBTB17 ESR2 11117529 14525934 25348397 N/A experimental interaction detection,physical interaction,biochemical,in vitro ComPPI,HPRD
ZBTB17 PGR 11117529 14525934 25348397 N/A experimental interaction detection,physical interaction,biochemical,in vitro ComPPI,HPRD
ZBTB17 ESR1 11117529 14525934 25348397 N/A experimental interaction detection,physical interaction,biochemical,in vitro ComPPI,HPRD
ZBTB17 HK3 11068878 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
ZBTB17 TOPBP1 12408820 14525934 17006541 18923429 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct,OmniPath
ZBTB17 MAX 25348397 N/A physical interaction ComPPI
ZBTB17 MYCN 21123453 21908575 24234451 25348397 26766587 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
ZBTB17 TMPRSS11A 14525934 15095404 25348397 27898060 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
ZBTB17 HSP90AA2P 25348397 N/A physical interaction ComPPI
ZBTB17 ZBTB49 25348397 N/A physical interaction ComPPI
ZBTB17 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
ZBTB17 ZBTB4 25348397 N/A physical interaction ComPPI
ZBTB17 GFI1 19164764 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB17 CDKN2A 25348397 N/A physical interaction ComPPI
ZBTB17 TP53 25348397 N/A physical interaction ComPPI
ZBTB17 BCL6 25348397 N/A physical interaction ComPPI
ZBTB17 DACT1 25348397 N/A physical interaction ComPPI
ZBTB17 ZBTB7C 25348397 N/A physical interaction ComPPI
ZBTB17 UBE2H 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZBTB17 CDKN1A 17828269 27898060 inhibition,stimulant N/A OmniPath
MYC ZBTB17 11283613 16352593 17145710 17418410 18923429 19786833 20426839 20697356 26766587 27898060 9312026 inhibition N/A OmniPath
ZBTB17 MYC 11283613 16352593 17145710 17418410 18923429 19786833 20426839 20697356 26766587 27898060 9312026 N/A N/A OmniPath
BCL6 ZBTB17 16142238 17828269 27898060 inhibition N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B1B5A ZBTB17 27087310 direct interaction,inhibition N/A NPInter
URS00008C3792 ZBTB17 27087310 direct interaction,inhibition N/A NPInter

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