Gene Information gene info

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GENE：UVRAG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UVRAG
FullNmae UV radiation resistance associated
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12640
EnsembleID ENSG00000198382
Uniprot Q9P2Y5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UVRAG mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UVRAG immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UVRAG entotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UVRAG entotic_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
UVRAG autophagy 31905312 UVRAG is one of the key players of autophagy, but its role in vivo remained puzzling. retulator signature
UVRAG autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
UVRAG GO:0000149,GO:0000323,GO:0000421,GO:0000775,GO:0005515,GO:0005737,GO:0005764,GO:0005768,GO:0005769,GO:0005770,GO:0005783,GO:0005813,GO:0006281,GO:0006890,GO:0006914,GO:0007051,GO:0007059,GO:0007098,GO:0010506,GO:0017124,GO:0030496,GO:0032465,GO:0032801,GO:0033116,GO:0035032,GO:0035493,GO:0036092,GO:0045335,GO:0046718,GO:0051684,GO:0071900,GO:0071985,GO:0097352,GO:0097680,GO:1901098

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UVRAG hsa:7405 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BCL2 UVRAG 10604474 11704864 16179260 17106237 17446862 17891140 18612260 22039431 22885520 23064052 23377657 23430059 23850759 26192618 27754749 8929532 9765397 interaction type N/A ACSN
UVRAG BECN1 10604474 10949026 11085534 11704864 12667443 16179260 16227588 17106237 17446862 17891140 18097445 18612260 18843052 19265852 22039431 22093031 22166994 22421439 22836101 22885520 23030059 23064052 23180781 23301705 23377657 23430059 23725295 23850759 24070470 26192618 27754749 28645028 8929532 9765397 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
UVRAG ATG14 16227588 17106237 17446862 17891140 18612260 19265852 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 26192618 27754749 28645028 interaction type N/A ACSN
UVRAG PIK3C3 16227588 17106237 17446862 17891140 18612260 18843052 19265852 22093031 22166994 22421439 22885520 23030059 23180781 23301705 23377657 23725295 24070470 26192618 27754749 28645028 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
BECN1 UVRAG 18641390 18843052 19050071 19270696 23180781 physical association anti tag coimmunoprecipitation,two hybrid,isothermal titration calorimetry,pull down,tandem affinity purification InnateDB
PIK3C3 UVRAG 18843052 23180781 physical association anti tag coimmunoprecipitation InnateDB
UVRAG SH3GLB1 17891140 23180781 physical association anti tag coimmunoprecipitation InnateDB
RUBCN UVRAG 22423967 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 UVRAG 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 UVRAG 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UVRAG 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 UVRAG 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 UVRAG 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYCN UVRAG 16093321 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 UVRAG 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 UVRAG 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB UVRAG 22228303 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000285DCB UVRAG 22356768 22743998 mrna cleavage,inhibition N/A miRDeathDB
URS00004DA9DB UVRAG 22421148 25416803 25939713 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002C0FCB UVRAG 22228303 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000F31F4 UVRAG 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 UVRAG 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00002FC5B0 UVRAG 20371350 22473208 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00003D5391 UVRAG 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 UVRAG 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 UVRAG 25202981 25416803 mrna cleavage,inhibition array technology,rna immunoprecipitation,quantitative reverse transcription pcr TarBase
URS00001C11BC UVRAG 25416803 26990571 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000016914 UVRAG 25416803 26181203 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000345DEB UVRAG 25416803 26717041 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
MTOR UVRAG 22135298 phosphorylation N/A PhosphoSite
UVRAG BECN1 25361965 interaction type N/A PTMCode2
BECN1 UVRAG 25361965 interaction type N/A PTMCode2
PIK3C3 UVRAG 25361965 interaction type N/A PTMCode2
UVRAG PIK3C3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF3G UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB39A UVRAG 24234451 24349490 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 UVRAG 17891140 24056303 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF5B UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
VPS11 UVRAG 14525934 18552835 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CALM1 UVRAG 25348397 N/A anti tag coimmunoprecipitation ComPPI
RINT1 UVRAG 24056303 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,pull down,physical interaction ComPPI,IntAct
SLAMF1 UVRAG 22493499 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
FEZ1 UVRAG 22354037 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
RBX1 UVRAG 25348397 N/A physical interaction ComPPI
PTPRA UVRAG 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RUBCN UVRAG 20562859 21062745 22493499 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
COPB2 UVRAG 24056303 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IQGAP2 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RALB UVRAG 25348397 N/A physical interaction ComPPI
XPO1 UVRAG 25348397 N/A physical interaction ComPPI
CLPB UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CUL4A UVRAG 25348397 N/A physical interaction ComPPI
YWHAE UVRAG 25348397 N/A physical interaction ComPPI
TGFBRAP1 UVRAG 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HECTD1 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GYG1 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 UVRAG 19050071 20562859 21597469 22081109 22493499 23954414 24034250 24056303 24234451 25348397 25490155 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,electron microscopy,molecular sieving,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAX UVRAG 21597469 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
PIK3C3 UVRAG 20562859 22493499 24056303 24234451 24785657 24849286 25348397 25490155 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PURB UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DFFA UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDB2 UVRAG 25348397 N/A physical interaction ComPPI
DDB1 UVRAG 25348397 N/A physical interaction ComPPI
EIF3B UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PIK3R4 UVRAG 20562859 22493499 24234451 25348397 25490155 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
VPS18 UVRAG 14525934 18552835 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
VPS16 UVRAG 14525934 18552835 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VPS33A UVRAG 20562859 24234451 24554770 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZW10 UVRAG 24056303 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EDARADD UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GYS1 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SPTLC1 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CDC42EP1 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TOP2B UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BRCC3 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYO1C UVRAG 25348397 N/A physical interaction ComPPI
NUP160 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AGL UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
STX18 UVRAG 24056303 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USP18 UVRAG 25348397 N/A physical interaction ComPPI
CPNE7 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
VPS33B UVRAG 14525934 18552835 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PPP2R2D UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NBAS UVRAG 24056303 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UVRAG RUBCNL 20562859 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UVRAG ACSL4 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UVRAG RGPD4 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UVRAG TUBAL3 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UVRAG RPF2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UVRAG RPS27L 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UVRAG ZNF768 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UVRAG BECN2 23954414 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
VPS39 UVRAG 25348397 N/A physical interaction ComPPI
WDR6 UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PASK UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UVRAG UVRAG 20562859 24234451 association,physical association anti tag coimmunoprecipitation IntAct
UVRAG CALM2 20562859 24234451 association anti tag coimmunoprecipitation IntAct
UVRAG SH3GLB1 17891140 18032918 21068542 27898060 stimulant N/A OmniPath
SH3GLB1 UVRAG 17891140 18032918 21068542 27898060 stimulant N/A OmniPath
UVRAG PIK3C3 18843052 20562859 24785657 24980960 27898060 stimulant N/A OmniPath
UVRAG BECN1 16799551 17106237 18641390 18843052 19050071 19172397 19270696 20562859 21311563 21597469 22081109 23878393 23954414 24034250 26496610 27898060 inhibition,stimulant N/A OmniPath
TP73 UVRAG 19001857 27898060 inhibition N/A OmniPath
MTOR UVRAG 25533187 26139536 27898060 N/A N/A OmniPath
UVRAG PIK3R4 18957027 27898060 stimulant N/A OmniPath
TFEB UVRAG 21617040 27898060 N/A N/A OmniPath

Visualization










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