Gene Information gene info

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GENE：TSC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TSC1
FullNmae TSC complex subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12362
EnsembleID ENSG00000165699
Uniprot Q92574

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TSC1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSC1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSC1 autophagy 38593872 Moreover, our experiment using knockdown of TSC1 resulted in chondrocytes expressing lower levels of autophagy. retulator signature
TSC1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TSC1 GO:0001822,GO:0001843,GO:0001952,GO:0002250,GO:0005515,GO:0005634,GO:0005737,GO:0005765,GO:0005811,GO:0005829,GO:0005829,GO:0005884,GO:0005886,GO:0005938,GO:0006407,GO:0006417,GO:0006813,GO:0007160,GO:0008285,GO:0008285,GO:0008306,GO:0008344,GO:0009267,GO:0014069,GO:0016020,GO:0016242,GO:0017148,GO:0021766,GO:0021987,GO:0030027,GO:0030030,GO:0030544,GO:0032007,GO:0032007,GO:0032007,GO:0032007,GO:0032780,GO:0032868,GO:0032991,GO:0033596,GO:0033596,GO:0033596,GO:0033596,GO:0042030,GO:0042552,GO:0043379,GO:0043666,GO:0045792,GO:0046323,GO:0048471,GO:0050808,GO:0050821,GO:0050821,GO:0051087,GO:0051492,GO:0051726,GO:0051879,GO:0051894,GO:0055007,GO:0090630,GO:0090650,GO:0101031,GO:1904262

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TSC1 hsa:7248 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04140 Autophagy - animal - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04218 Cellular senescence - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04714 Thermogenesis - Homo sapiens (human)
TSC1 hsa:7248 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
TSC1 hsa:7248 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
TSC1 hsa:7248 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
TSC1 hsa:7248 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
TSC1 hsa:7248 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TSC2 TSC1 10807585 10915759 11175345 11290735 11741832 11741833 12150915 12167664 12172553 12176984 12869586 12906785 14551205 14651849 15342917 15611338 15851026 15851513 15963462 16339216 16424383 16556040 16636147 16678438 16959574 17077083 17604271 17658474 17680028 17693255 18198340 18411301 18481918 18692468 18974095 19022819 19027299 19339977 20146692 20226003 21071413 21533173 21621563 21708191 23030059 23180781 23331499 26192618 26597054 27328425 9069260 9580671 phosphorylation reaction,stimulation,association,physical association anti tag coimmunoprecipitation,protein kinase assay ACSN,InnateDB,SignaLink,SignaLink
TSC1 RHEB 12906785 14551205 16636147 17604271 17680028 17693255 19022819 20146692 26192618 interaction type N/A ACSN
AKT1 TSC1 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 26192618 9812896 interaction type N/A ACSN
SESN2 TSC1 14651849 15509864 15980064 16054095 16054096 17244528 18692468 19037093 19197243 19339977 20484410 26192618 interaction type N/A ACSN
DDIT4 TSC1 18198340 19557001 26192618 interaction type N/A ACSN
DAPK1 TSC1 11323415 17703233 18974095 19180116 26192618 interaction type N/A ACSN
CDK1 TSC1 11444800 14551205 15279786 17303408 17660363 18414028 18590585 23180781 26192618 7575488 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
TSC1 RAC1 11955434 12829230 12906785 15611338 15851026 15967165 16636147 17680028 18974095 19022819 20146692 26192618 interaction type N/A ACSN
RICTOR TSC1 18411301 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPKAP1 TSC1 18411301 23180781 physical association anti tag coimmunoprecipitation InnateDB
MLST8 TSC1 18411301 23180781 physical association anti tag coimmunoprecipitation InnateDB
YWHAZ TSC1 12176984 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
CCNB1 TSC1 11444800 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC1 DOCK7 15963462 23180781 physical association anti tag coimmunoprecipitation InnateDB
GSK3B TSC1 15972957 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC1 EZR 10806479 23180781 physical association anti tag coimmunoprecipitation InnateDB
RB1CC1 TSC1 16043512 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
PPP1R15A TSC1 17273797 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB TSC1 17693255 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
FTH1 TSC1 17355907 23180781 physical association two hybrid InnateDB
NDUFB10 TSC1 17355907 23180781 physical association two hybrid InnateDB
RASA1 TSC1 17355907 23180781 physical association two hybrid InnateDB
RAB11FIP5 TSC1 17355907 23180781 physical association two hybrid InnateDB
ACTB TSC1 17355907 23180781 physical association two hybrid InnateDB
RASSF7 TSC1 17355907 23180781 physical association two hybrid InnateDB
TSC1 ID3 17355907 23180781 physical association two hybrid InnateDB
HBA1 TSC1 17355907 23180781 physical association two hybrid InnateDB
EIF3F TSC1 17355907 23180781 physical association two hybrid InnateDB
TSC1 SFPQ 17355907 23180781 physical association two hybrid InnateDB
ACTA2 TSC1 17355907 23180781 physical association two hybrid InnateDB
CD63 TSC1 17355907 23180781 physical association two hybrid InnateDB
TSC1 SDCCAG8 17355907 23180781 physical association two hybrid InnateDB
MNAT1 TSC1 17355907 23180781 physical association two hybrid InnateDB
BEX3 TSC1 17355907 23180781 physical association two hybrid InnateDB
CDKN1B TSC1 15355997 23180781 physical association anti tag coimmunoprecipitation InnateDB
PLK1 TSC1 16339216 23180781 physical association anti tag coimmunoprecipitation InnateDB
TBC1D7 TSC1 17658474 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
TSC1 TSC2 17658474 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC1 TBC1D7 17658474 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC1 FBXW5 18381890 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUL4A TSC1 18381890 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC1 PATJ 17234746 23180781 physical association anti tag coimmunoprecipitation InnateDB
NEFL TSC1 12226091 23180781 physical association two hybrid,pull down InnateDB
TSC1 NEFL 12226091 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
TSC1 AKT1 12167664 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
TSC1 GSK3B 20005715 interaction type N/A PSP
TSC1 PTK2 20005715 interaction type N/A PSP
TSC1 RHEB 20005715 interaction type N/A PSP,SignaLink
TSC1 RPS6KA1 20005715 interaction type N/A PSP,SignaLink
TSC1 GSK3B 12511557 20005715 20005715 21071413 N/A N/A SignaLink
TSC1 PTK2 17043358 20005715 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR TSC1 20610535 21036700 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 TSC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 TSC1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TSC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TSC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TSC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TSC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TSC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TSC1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002FC5B0 TSC1 22431589 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002FC5B0 TSC1 22431589 22473208 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 TSC1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000AA464 TSC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 TSC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD TSC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065FDF TSC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000358C16 TSC1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 TSC1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 TSC1 25416803 25452577 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002E857A TSC1 25416803 25915427 26458815 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 TSC1 22135298 phosphorylation N/A PhosphoSite
IKBKB TSC1 22135298 phosphorylation N/A PhosphoSite
RHEB TSC1 25361965 interaction type N/A PTMCode2
TSC1 RHEB 25361965 interaction type N/A PTMCode2
YWHAE TSC1 25361965 interaction type N/A PTMCode2
TSC1 YWHAE 25361965 interaction type N/A PTMCode2
AXIN1 TSC1 25361965 interaction type N/A PTMCode2
TSC1 AXIN1 25361965 interaction type N/A PTMCode2
TSC1 PLK1 25361965 interaction type N/A PTMCode2
PLK1 TSC1 25361965 interaction type N/A PTMCode2
TSC1 YWHAB 25361965 interaction type N/A PTMCode2
YWHAB TSC1 25361965 interaction type N/A PTMCode2
TSC1 PAM 25361965 interaction type N/A PTMCode2
PAM TSC1 25361965 interaction type N/A PTMCode2
TSC1 YWHAG 25361965 interaction type N/A PTMCode2
YWHAG TSC1 25361965 interaction type N/A PTMCode2
TSC1 FBXW5 25361965 interaction type N/A PTMCode2
FBXW5 TSC1 25361965 interaction type N/A PTMCode2
TSC1 GSK3B 25361965 interaction type N/A PTMCode2
GSK3B TSC1 25361965 interaction type N/A PTMCode2
TSC1 EZR 25361965 interaction type N/A PTMCode2
EZR TSC1 25361965 interaction type N/A PTMCode2
TSC1 DOCK7 25361965 interaction type N/A PTMCode2
DOCK7 TSC1 25361965 interaction type N/A PTMCode2
TSC1 NF2 25361965 interaction type N/A PTMCode2
NF2 TSC1 25361965 interaction type N/A PTMCode2
TSC1 TBC1D7 25361965 interaction type N/A PTMCode2
TBC1D7 TSC1 25361965 interaction type N/A PTMCode2
TSC1 MSN 25361965 interaction type N/A PTMCode2
MSN TSC1 25361965 interaction type N/A PTMCode2
CDKN1B TSC1 25361965 interaction type N/A PTMCode2
TSC1 CDKN1B 25361965 interaction type N/A PTMCode2
AKT1 TSC1 25361965 interaction type N/A PTMCode2
TSC1 AKT1 25361965 interaction type N/A PTMCode2
YWHAH TSC1 25361965 interaction type N/A PTMCode2
TSC1 YWHAH 25361965 interaction type N/A PTMCode2
YWHAQ TSC1 25361965 interaction type N/A PTMCode2
TSC1 YWHAQ 25361965 interaction type N/A PTMCode2
CCNB1 TSC1 25361965 interaction type N/A PTMCode2
TSC1 CCNB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CIAO1 TSC1 25348397 N/A physical interaction ComPPI
TBC1D7 TSC1 14525934 17658474 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FTH1 TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDKN1B TSC1 25348397 N/A physical interaction ComPPI
ACTB TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
YWHAG TSC1 14525934 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ATXN1 TSC1 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HBA1 TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
NF2 TSC1 12226091 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAPK14 TSC1 20368287 24234451 25348397 physical association pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SFPQ TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
DOCK7 TSC1 25348397 N/A physical interaction ComPPI
GSK3B TSC1 25348397 N/A physical interaction ComPPI
PAM TSC1 25348397 N/A physical interaction ComPPI
YWHAB TSC1 12176984 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
YWHAZ TSC1 12176984 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
AXIN1 TSC1 25348397 N/A physical interaction ComPPI
RUVBL1 TSC1 25348397 N/A physical interaction ComPPI
TNS2 TSC1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PLK1 TSC1 14525934 16339216 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IKBKB TSC1 17693255 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,protein kinase assay ComPPI,IntAct
RPS6KA1 TSC1 25348397 N/A physical interaction ComPPI
RDX TSC1 10806479 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
EIF3F TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSC2 TSC1 10585443 10915759 11175345 11290735 11741833 12511557 12869586 14525934 15342917 15963462 16424383 17658474 17693255 20412061 21134130 24234451 25263562 25348397 9580671 9809973 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
RIN3 TSC1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
YWHAQ TSC1 12176984 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MNAT1 TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
ID3 TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
RASA1 TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
YWHAH TSC1 12176984 14525934 17979178 24234451 25348397 association experimental interaction detection,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
YWHAE TSC1 12176984 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NGFR TSC1 17355907 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
URI1 TSC1 25348397 N/A physical interaction ComPPI
HSH2D TSC1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
CCNB1 TSC1 11444800 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RHEB TSC1 25348397 N/A physical interaction ComPPI
TSC1 MSN 12226091 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TSC1 EZR 10806479 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TSC1 AKT1 12167664 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TSC1 ACTA1 25348397 N/A physical interaction ComPPI
TSC1 CDK1 11444800 14525934 14551205 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TSC1 PTK2 25348397 N/A physical interaction ComPPI
TSC1 FBXW5 25348397 N/A physical interaction ComPPI
TSC1 BECN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSC1 BEX3 17355907 24234451 25348397 colocalization,physical association two hybrid,pull down,physical interaction,confocal microscopy ComPPI,IntAct
TSC1 ESR1 25348397 N/A physical interaction ComPPI
TSC1 KDM1A 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TSC1 PRMT6 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TSC1 MOV10 25348397 N/A physical interaction ComPPI
TSC1 NXF1 25348397 N/A physical interaction ComPPI
TSC1 DAPK1 21134130 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TSC1 RRAGA 25348397 N/A physical interaction ComPPI
TSC1 RRAGC 25348397 N/A physical interaction ComPPI
TSC1 AKTIP 25348397 N/A physical interaction ComPPI
TSC1 SH2D2A 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
TSC1 APPL2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSC1 DOK5 25348397 N/A physical interaction ComPPI
TSC1 PPM1H 25348397 N/A physical interaction ComPPI
TSC1 CPVL 25348397 N/A physical interaction ComPPI
TSC1 DYRK1A 25348397 N/A physical interaction ComPPI
TSC1 PCM1 25348397 N/A physical interaction ComPPI
TSC1 PIH1D1 25348397 N/A physical interaction ComPPI
TSC1 RPAP3 25348397 N/A physical interaction ComPPI
TSC1 RUVBL2 25348397 N/A physical interaction ComPPI
TSC1 DNAAF10 25348397 N/A physical interaction ComPPI
TSC1 SDCCAG8 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSC1 RAB11FIP5 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSC1 CD63 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSC1 NDUFB10 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSC1 ACTA2 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSC1 RASSF7 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSC1 ETS1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
NEFL TSC1 12226091 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TSC1 TSC1 17355907 24234451 physical association two hybrid IntAct
GOLGA4 TSC1 24234451 30021884 physical association cross-linking study IntAct
ACTB TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 ACTB 17355907 27898060 N/A N/A OmniPath
PRKAA2 TSC1 14651849 27898060 stimulant N/A OmniPath
PLK1 TSC1 16339216 27898060 N/A N/A OmniPath
MAPKAPK2 TSC1 18075516 27898060 inhibition N/A OmniPath
TSC1 SFPQ 17355907 27898060 N/A N/A OmniPath
CDKN1B TSC1 15355997 27898060 N/A N/A OmniPath
PPP1R15A TSC1 17273797 27898060 N/A N/A OmniPath
MLST8 TSC1 18411301 27898060 N/A N/A OmniPath
AKT1 TSC1 12167664 15342917 16288292 27898060 inhibition,stimulant N/A OmniPath
RICTOR TSC1 18411301 27898060 N/A N/A OmniPath
TSC1 YWHAZ 12176984 27898060 N/A N/A OmniPath
TSC1 RHEB 20006481 27898060 inhibition N/A OmniPath
TSC1 EIF3F 17355907 27898060 N/A N/A OmniPath
TSC1 EZR 10806479 27898060 N/A N/A OmniPath
CDK1 TSC1 11444800 14551205 15963462 20006582 27898060 inhibition,stimulant N/A OmniPath
TSC1 CDK1 11444800 14551205 27898060 N/A N/A OmniPath
ACTA2 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 ACTA2 17355907 27898060 N/A N/A OmniPath
RB1CC1 TSC1 16043512 27898060 inhibition N/A OmniPath
TSC2 TSC1 10585443 10807585 10915759 11175345 11290735 11741832 11741833 12147258 12167664 12176984 12511557 12869586 14551205 14651849 15340059 15342917 15851026 15851513 15963462 16339216 16424383 16464865 16636147 17077083 17355907 17658474 17693255 18411301 20166753 20412061 21134130 27898060 9580671 9809973 inhibition,stimulant N/A OmniPath
TSC1 TSC2 10585443 10807585 10915759 11175345 11290735 11741832 11741833 12147258 12167664 12176984 12511557 12869586 14551205 14651849 15340059 15342917 15851026 15851513 15963462 16339216 16424383 16464865 16636147 17077083 17355907 17658474 17693255 18411301 20166753 20412061 21134130 27898060 9580671 9809973 stimulant N/A OmniPath
MAPK1 TSC1 15851026 17671177 27898060 inhibition N/A OmniPath
TSC1 CCNB1 11444800 27898060 N/A N/A OmniPath
TSC1 MTOR 12271141 27898060 inhibition,stimulant N/A OmniPath
TSC1 GSK3B 15972957 27898060 N/A N/A OmniPath
CUL4A TSC1 18381890 27898060 N/A N/A OmniPath
IKBKB TSC1 17693255 18075516 19188143 24135021 27898060 inhibition N/A OmniPath
TSC1 IKBKB 17693255 27898060 N/A N/A OmniPath
ID3 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 ID3 17355907 27898060 N/A N/A OmniPath
SDCCAG8 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 SDCCAG8 17355907 27898060 N/A N/A OmniPath
NEFL TSC1 12226091 27898060 N/A N/A OmniPath
FTH1 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 FTH1 17355907 27898060 N/A N/A OmniPath
TSC1 DOCK7 15963462 27898060 N/A N/A OmniPath
FBXW5 TSC1 18381890 27898060 N/A N/A OmniPath
MNAT1 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 MNAT1 17355907 27898060 N/A N/A OmniPath
NDUFB10 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 NDUFB10 17355907 27898060 N/A N/A OmniPath
PATJ TSC1 17234746 27898060 N/A N/A OmniPath
TSC1 SEPTIN9 17355907 27898060 N/A N/A OmniPath
TSC1 RASSF7 17355907 27898060 N/A N/A OmniPath
RASA1 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 RASA1 17355907 27898060 N/A N/A OmniPath
TSC1 RAB11FIP5 17355907 27898060 N/A N/A OmniPath
TBC1D7 TSC1 17658474 26186194 27898060 stimulant N/A OmniPath
TSC1 CD63 17355907 27898060 N/A N/A OmniPath
TSC1 BEX3 17355907 27898060 N/A N/A OmniPath
MAPKAP1 TSC1 18411301 27898060 N/A N/A OmniPath

Visualization










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