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GENE：FAIM2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FAIM2
FullNmae Fas apoptotic inhibitory molecule 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17067
EnsembleID ENSG00000135472
Uniprot Q9BWQ8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FAIM2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FAIM2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FAIM2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FAIM2 GO:0002931,GO:0005515,GO:0005783,GO:0005794,GO:0016020,GO:0021549,GO:0021680,GO:0021681,GO:0021702,GO:0043066,GO:0043523,GO:0043524,GO:0045121,GO:0045211,GO:0051402,GO:0097190,GO:1902042,GO:2001234

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 FAIM2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FAIM2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FAIM2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 FAIM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002F74F1 FAIM2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRIM21 FAIM2 25348397 N/A physical interaction ComPPI
STK11 FAIM2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FAS FAIM2 10535980 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath

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