GENE:EMP2
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | EMP2 |
FullNmae | epithelial membrane protein 2 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:3334 |
EnsembleID | ENSG00000213853 |
Uniprot | P54851 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
EMP2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
EMP2 | autophagy | 39866225 | Conversely, overexpression of EMP2 enhances the invasive capacity of HCC cells and induces autophagy. | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
EMP2 | GO:0000139,GO:0001765,GO:0001787,GO:0001913,GO:0001952,GO:0001954,GO:0003093,GO:0005178,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005794,GO:0005794,GO:0005829,GO:0005886,GO:0005886,GO:0006915,GO:0007015,GO:0007155,GO:0007155,GO:0007160,GO:0007566,GO:0008284,GO:0009986,GO:0010594,GO:0016020,GO:0016324,GO:0016477,GO:0019900,GO:0019901,GO:0019901,GO:0031410,GO:0032060,GO:0032147,GO:0034394,GO:0034394,GO:0043534,GO:0043549,GO:0044854,GO:0045022,GO:0045121,GO:0045177,GO:0045765,GO:0045765,GO:0045766,GO:0048471,GO:0060136,GO:0060914,GO:0062043,GO:0070252,GO:0072659,GO:1990266,GO:2001046,GO:2001046,GO:2001212 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
EMP2 | hsa:2013 | path:hsa04510 | Focal adhesion - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | EMP2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
GATA1 | EMP2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | EMP2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
TFAP2C | EMP2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | EMP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000277201 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000237E04 | EMP2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075B538 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001FC26E | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000160683 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C5969 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005C1F22 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000045147B | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000544FF1 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000EEE35 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000054A671 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000195F5B | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003AA845 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000043F369 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006DA05 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002ECEE4 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000043D2C1 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004BC299 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C0FCB | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008AA34 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000118224 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C02E4 | EMP2 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000486E0B | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000047A67D | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000451A1 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E226A | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000016FD1A | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000021D7C8 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003ACE11 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001F0C23 | EMP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005DEC41 | EMP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000BF7F9 | EMP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000049FAE8 | EMP2 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |