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GENE：HDAC6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HDAC6
FullNmae histone deacetylase 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14064
EnsembleID ENSG00000094631
Uniprot Q9UBN7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HDAC6 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
HDAC6 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
HDAC6 autophagy 34944907 Specifically, the ubiquitin-binding histone deacetylase (HDAC) enzyme HDAC6 is known to be an important player in modulating autophagy. retulator signature
HDAC6 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
HDAC6 GO:0000118,GO:0000118,GO:0000122,GO:0000978,GO:0001222,GO:0001975,GO:0003779,GO:0004407,GO:0004407,GO:0004407,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0005771,GO:0005813,GO:0005829,GO:0005829,GO:0005829,GO:0005874,GO:0005875,GO:0005901,GO:0006476,GO:0006476,GO:0006476,GO:0006515,GO:0006886,GO:0006914,GO:0007026,GO:0008013,GO:0008017,GO:0008017,GO:0008134,GO:0008270,GO:0010506,GO:0010634,GO:0010727,GO:0016234,GO:0016235,GO:0016235,GO:0016241,GO:0016575,GO:0019896,GO:0019899,GO:0030424,GO:0030425,GO:0031252,GO:0031333,GO:0031593,GO:0031625,GO:0031647,GO:0031648,GO:0032418,GO:0032984,GO:0033138,GO:0033558,GO:0034983,GO:0035902,GO:0035967,GO:0036064,GO:0042826,GO:0042903,GO:0042903,GO:0042903,GO:0042903,GO:0042903,GO:0043014,GO:0043130,GO:0043162,GO:0043204,GO:0043242,GO:0045598,GO:0045814,GO:0045861,GO:0045892,GO:0048156,GO:0048156,GO:0048156,GO:0048156,GO:0048471,GO:0048487,GO:0048668,GO:0048843,GO:0050775,GO:0051354,GO:0051412,GO:0051787,GO:0051788,GO:0051879,GO:0051968,GO:0060271,GO:0060632,GO:0060765,GO:0060997,GO:0061523,GO:0061523,GO:0061734,GO:0070201,GO:0070301,GO:0070840,GO:0070842,GO:0070845,GO:0070848,GO:0071218,GO:0071374,GO:0071548,GO:0090042,GO:0090042,GO:0090042,GO:0090044,GO:1900409,GO:1901984,GO:1903146,GO:1904056,GO:1904115,GO:2000273

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HDAC6 hsa:10013 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
HDAC6 hsa:10013 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
HDAC6 hsa:10013 path:hsa05034 Alcoholism - Homo sapiens (human)
HDAC6 hsa:10013 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELAVL1 HDAC6 18644987 23180781 physical association anti tag coimmunoprecipitation InnateDB
ERBB2 HDAC6 18644987 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
PLAA HDAC6 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
ETS1 HDAC6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HDAC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HDAC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HDAC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HDAC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HDAC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HDAC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 HDAC6 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000096022 HDAC6 22375943 25416803 28195408 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000027464B HDAC6 25416803 27349231 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 HDAC6 22135298 phosphorylation N/A PhosphoSite
MAPK3 HDAC6 22135298 phosphorylation N/A PhosphoSite
MAPK1 HDAC6 22135298 phosphorylation N/A PhosphoSite
EGFR HDAC6 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HNRNPK HDAC6 25348397 N/A physical interaction ComPPI
MAPRE1 HDAC6 25348397 N/A physical interaction ComPPI
KRT18 HDAC6 25348397 N/A physical interaction ComPPI
DYNLL1 HDAC6 25348397 N/A physical interaction ComPPI
TRIM21 HDAC6 25348397 N/A physical interaction ComPPI
ABT1 HDAC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLAA HDAC6 11689694 14525934 23752268 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HSPA8 HDAC6 25348397 N/A physical interaction ComPPI
HSPA2 HDAC6 25348397 N/A physical interaction ComPPI
FBP1 HDAC6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RPS7 HDAC6 25348397 N/A physical interaction ComPPI
PPP1CC HDAC6 25348397 N/A physical interaction ComPPI
BAG3 HDAC6 25348397 N/A physical interaction ComPPI
ISG15 HDAC6 25348397 N/A physical interaction ComPPI
ATP5F1B HDAC6 25348397 N/A physical interaction ComPPI
NPM1 HDAC6 25348397 N/A physical interaction ComPPI
PCNA HDAC6 25348397 N/A physical interaction ComPPI
MSH3 HDAC6 25348397 N/A physical interaction ComPPI
CDKN1A HDAC6 25348397 N/A physical interaction ComPPI
ACTG1 HDAC6 25348397 N/A physical interaction ComPPI
SMARCC1 HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB HDAC6 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
KPNA1 HDAC6 25348397 N/A physical interaction ComPPI
NUDCD3 HDAC6 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ACTB HDAC6 25348397 N/A physical interaction ComPPI
RPS15 HDAC6 25348397 N/A physical interaction ComPPI
UBE2D1 HDAC6 25348397 N/A physical interaction ComPPI
BRMS1 HDAC6 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
MCM2 HDAC6 25348397 N/A physical interaction ComPPI
HSP90AB1 HDAC6 25348397 N/A physical interaction ComPPI
UBL7 HDAC6 25348397 N/A physical interaction ComPPI
H4C1 HDAC6 10220385 24234451 25348397 deacetylation reaction physical interaction,deacetylase assay ComPPI,IntAct
ERBB2 HDAC6 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
MAPK1 HDAC6 25348397 N/A physical interaction ComPPI
SYK HDAC6 25348397 N/A physical interaction ComPPI
NEK3 HDAC6 25348397 N/A physical interaction ComPPI
ERBB4 HDAC6 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
SMAD7 HDAC6 25348397 N/A physical interaction ComPPI
PTPN11 HDAC6 25348397 N/A physical interaction ComPPI
PRKCA HDAC6 21949397 21952047 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
NAV2 HDAC6 25348397 N/A physical interaction ComPPI
MAPK3 HDAC6 25348397 N/A physical interaction ComPPI
KHDRBS1 HDAC6 25348397 N/A physical interaction ComPPI
RUNX2 HDAC6 12391164 14525934 23618908 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
EP300 HDAC6 14525934 15102857 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ATF3 HDAC6 25348397 N/A physical interaction ComPPI
HIF1A HDAC6 25348397 N/A physical interaction ComPPI
USP7 HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JDP2 HDAC6 25348397 N/A physical interaction ComPPI
NONO HDAC6 25348397 N/A physical interaction ComPPI
TWIST1 HDAC6 25348397 N/A physical interaction ComPPI
PKN1 HDAC6 19036992 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ARHGDIA HDAC6 25348397 N/A physical interaction ComPPI
GSK3B HDAC6 25348397 N/A physical interaction ComPPI
GAPDH HDAC6 25348397 N/A physical interaction ComPPI
YWHAZ HDAC6 25348397 N/A physical interaction ComPPI
TUBA1B HDAC6 12606581 14525934 23703321 23798680 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PFKP HDAC6 25348397 N/A physical interaction ComPPI
PFKL HDAC6 25348397 N/A physical interaction ComPPI
UBB HDAC6 12354939 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
UBC HDAC6 12354939 15171253 17512543 20129057 21690293 24023063 24035499 24234451 25342804 25348397 25429107 27898060 physical association two hybrid,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
RPS27A HDAC6 25348397 N/A in vitro,in vivo ComPPI
UBA52 HDAC6 25348397 N/A in vitro,in vivo ComPPI
DLD HDAC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSP90AA1 HDAC6 25348397 N/A physical interaction ComPPI
NTRK1 HDAC6 25348397 N/A physical interaction ComPPI
ENO1 HDAC6 25348397 N/A physical interaction ComPPI
CAV1 HDAC6 18356165 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
XRCC5 HDAC6 25348397 N/A physical interaction ComPPI
STIP1 HDAC6 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HSPA5 HDAC6 25348397 N/A physical interaction ComPPI
HSPA1A HDAC6 25348397 N/A physical interaction ComPPI
HSPA1B HDAC6 25348397 N/A physical interaction ComPPI
MSH6 HDAC6 25348397 N/A physical interaction ComPPI
HSP90B1 HDAC6 25348397 N/A physical interaction ComPPI
POLDIP2 HDAC6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX4 HDAC6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP1CA HDAC6 25348397 N/A physical interaction ComPPI
PXN HDAC6 25070956 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HNRNPU HDAC6 25348397 N/A physical interaction ComPPI
MAPT HDAC6 18636984 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CBFA2T3 HDAC6 25348397 N/A physical interaction ComPPI
XRCC6 HDAC6 21847364 25299772 25348397 27898060 N/A physical interaction ComPPI,OmniPath
EEF1A1 HDAC6 25348397 N/A physical interaction ComPPI
CACYBP HDAC6 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TUBA4A HDAC6 12024216 14525934 24234451 25348397 colocalization experimental interaction detection,fluorescence microscopy,in vivo ComPPI,HPRD,IntAct
DCTN1 HDAC6 12024216 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
CAD HDAC6 25348397 N/A physical interaction ComPPI
CFTR HDAC6 14675537 22069321 25348397 27898060 N/A physical interaction ComPPI,OmniPath
GSK3A HDAC6 25348397 N/A physical interaction ComPPI
SQSTM1 HDAC6 22674379 24086678 25348397 26363065 27898060 N/A physical interaction ComPPI,OmniPath
PAWR HDAC6 25348397 N/A physical interaction ComPPI
RELA HDAC6 25348397 N/A physical interaction ComPPI
PSMD1 HDAC6 25348397 N/A physical interaction ComPPI
PKM HDAC6 25348397 N/A physical interaction ComPPI
RANBP9 HDAC6 25348397 N/A physical interaction ComPPI
PDHB HDAC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDHX HDAC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDHA1 HDAC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BCL11B HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATM HDAC6 25348397 N/A physical interaction ComPPI
GRK5 HDAC6 25348397 N/A physical interaction ComPPI
XPO1 HDAC6 22334690 25348397 26673895 27898060 N/A physical interaction ComPPI,OmniPath
PSMC5 HDAC6 25348397 N/A physical interaction ComPPI
NR0B2 HDAC6 25348397 N/A physical interaction ComPPI
ZBTB16 HDAC6 14525934 15467736 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GRK2 HDAC6 22193721 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
DIAPH3 HDAC6 25348397 N/A physical interaction ComPPI
RPS6 HDAC6 25348397 N/A physical interaction ComPPI
RPS18 HDAC6 25348397 N/A physical interaction ComPPI
RPLP2 HDAC6 25348397 N/A physical interaction ComPPI
SRSF2 HDAC6 21157427 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
IPO7 HDAC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSNK2A2 HDAC6 25348397 N/A physical interaction ComPPI
GEMIN5 HDAC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BIN1 HDAC6 25348397 N/A physical interaction ComPPI
ACTR1A HDAC6 25348397 N/A physical interaction ComPPI
ADRB2 HDAC6 25348397 N/A physical interaction ComPPI
MED9 HDAC6 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EGF HDAC6 20029029 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
EGFR HDAC6 20029029 24234451 24658140 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,ubiquitin reconstruction,physical interaction,protein kinase assay ComPPI,IntAct
TUBA1A HDAC6 12024216 19893491 24234451 25348397 deacetylation reaction,association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,IntAct
NR4A1 HDAC6 25348397 N/A physical interaction ComPPI
JAK2 HDAC6 25348397 N/A physical interaction ComPPI
TCP1 HDAC6 25348397 N/A physical interaction ComPPI
CDC20 HDAC6 25348397 N/A physical interaction ComPPI
TUBA8 HDAC6 25348397 N/A physical interaction ComPPI
CCT5 HDAC6 25348397 N/A physical interaction ComPPI
CCT7 HDAC6 25348397 N/A physical interaction ComPPI
CTTN HDAC6 21847094 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
HSPA4 HDAC6 25348397 N/A physical interaction ComPPI
SF3A1 HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRRAP HDAC6 25348397 N/A physical interaction ComPPI
MMS19 HDAC6 25348397 N/A physical interaction ComPPI
RASSF2 HDAC6 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HDAC6 BCOR 10898795 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC6 HDAC11 11948178 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HDAC6 SIRT2 12620231 14525934 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vivo ComPPI,HPRD,IntAct
HDAC6 BCL3 14525934 15469820 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC6 RELB 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
HDAC6 UBE2D3 25348397 N/A physical interaction ComPPI
HDAC6 UBE2H 25348397 N/A physical interaction ComPPI
HDAC6 UBE2E1 25348397 N/A physical interaction ComPPI
HDAC6 DNAJB6 25348397 N/A physical interaction ComPPI
HDAC6 DNAJB8 25348397 N/A physical interaction ComPPI
HDAC6 ERBB3 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
HDAC6 FNTA 25348397 N/A physical interaction ComPPI
HDAC6 FNTB 25348397 N/A physical interaction ComPPI
HDAC6 HSP90AA2P 25348397 N/A physical interaction ComPPI
HDAC6 TARDBP 25348397 N/A physical interaction ComPPI
HDAC6 CYLD 19893491 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 LCOR 12535528 19744931 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HDAC6 FAT1 25348397 N/A physical interaction ComPPI
HDAC6 UBD 19033385 21090589 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HDAC6 TUBB2B 25348397 N/A physical interaction ComPPI
HDAC6 TUBB2A 12606581 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
HDAC6 G3BP1 18079183 21532619 24234451 25348397 27898060 colocalization physical interaction,confocal microscopy ComPPI,IntAct,OmniPath
HDAC6 AURKA 25348397 N/A physical interaction ComPPI
HDAC6 TPPP 25348397 N/A physical interaction ComPPI
HDAC6 NR3C1 25348397 N/A physical interaction ComPPI
HDAC6 MIIP 20008322 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HDAC6 MYD88 25348397 N/A physical interaction ComPPI
HDAC6 POLA2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC6 HES1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC6 NASP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC6 BBS10 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC6 NACAD 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC6 ZNF205 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC6 LPXN 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC6 HSPB1 25348397 N/A physical interaction ComPPI
HDAC6 DYSF 22174839 24687993 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HDAC6 FBXO11 25348397 N/A physical interaction ComPPI
HDAC6 PTOV1 25348397 N/A physical interaction ComPPI
HDAC6 STUB1 24234451 25036637 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
HDAC6 RPL36A 25348397 N/A physical interaction ComPPI
HDAC6 BIRC5 25348397 N/A physical interaction ComPPI
HDAC6 BAX 25348397 N/A physical interaction ComPPI
HDAC6 TRIM50 22792322 24308962 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HDAC6 ATP13A2 22645275 24234451 25348397 physical association anti tag coimmunoprecipitation,ubiquitin reconstruction,physical interaction ComPPI,IntAct
HDAC6 VKORC1 25348397 N/A physical interaction ComPPI
HDAC6 SOD1 25348397 N/A physical interaction ComPPI
HDAC6 ACIN1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 DDX19A 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 CEP57 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 BDH1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 DNAJA1 23752268 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 IQCB1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 KDM1A 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 MRPL12 25348397 N/A physical interaction ComPPI
HDAC6 SLC25A10 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 TIMM50 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 NUP50 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 PUF60 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 USP9X 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 PML 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 SEC16A 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 SRRM2 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 USP47 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 ZMYM3 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 TRIM27 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 RAD23B 25348397 N/A physical interaction ComPPI
HDAC6 CNTLN 25348397 N/A physical interaction ComPPI
HDAC6 CENPJ 25348397 N/A physical interaction ComPPI
HDAC6 GBF1 25348397 N/A physical interaction ComPPI
HDAC6 CSE1L 25348397 N/A physical interaction ComPPI
HDAC6 MSH2 25348397 N/A physical interaction ComPPI
HDAC6 NR1H4 25348397 N/A physical interaction ComPPI
HDAC6 GANAB 25348397 N/A physical interaction ComPPI
HDAC6 MCM7 25348397 N/A physical interaction ComPPI
HDAC6 DDX1 25348397 N/A physical interaction ComPPI
HDAC6 HSPA1L 25348397 N/A physical interaction ComPPI
HDAC6 HSPA6 25348397 N/A physical interaction ComPPI
HDAC6 CCT3 25348397 N/A physical interaction ComPPI
HDAC6 TUBA1C 25348397 N/A physical interaction ComPPI
HDAC6 TUBB4B 25348397 N/A physical interaction ComPPI
HDAC6 MC1R 25348397 N/A physical interaction ComPPI
HDAC6 TUBB3 25348397 N/A physical interaction ComPPI
HDAC6 TUBB4A 25348397 N/A physical interaction ComPPI
HDAC6 PGK1 25348397 N/A physical interaction ComPPI
HDAC6 KMT5A 25348397 N/A physical interaction ComPPI
HDAC6 POLR1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HDAC6 SAV1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HDAC6 MEF2B 25348397 N/A physical interaction ComPPI
HDAC6 ATXN3 25348397 N/A physical interaction ComPPI
HDAC6 ELAVL1 25348397 N/A physical interaction ComPPI
HDAC6 DYNC1H1 25348397 N/A physical interaction ComPPI
HDAC6 MYH10 25348397 N/A physical interaction ComPPI
HDAC6 DDIT3 25348397 N/A physical interaction ComPPI
HDAC6 SHMT2 25348397 N/A physical interaction ComPPI
HDAC6 NXF1 25348397 N/A physical interaction ComPPI
HDAC6 RIPOR2 25348397 N/A physical interaction ComPPI
HDAC6 CLIP1 25348397 N/A physical interaction ComPPI
HDAC6 CTNNB1 18356165 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 KCNAB3 25348397 N/A physical interaction ComPPI
HDAC6 KAT5 25348397 N/A physical interaction ComPPI
HDAC6 BANP 25348397 N/A physical interaction ComPPI
HDAC6 AK2 25348397 N/A physical interaction ComPPI
HDAC6 BCKDHA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 BCKDHB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 CPT1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 DBT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 DLAT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 DLST 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 OGDH 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 IFRD2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 GTF3C5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 ZNF518A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 XPOT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 PKN3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 TMEM161A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 ATAD3A 25348397 N/A physical interaction ComPPI
HDAC6 ZMYM1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 UTP15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 UTP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 MRPS36 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 TBC1D16 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 GLOD5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 APOBEC3G 25348397 26105074 27898060 N/A physical interaction ComPPI,OmniPath
HDAC6 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HDAC6 CEP70 24234451 25348397 26112604 27898060 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
HDAC6 FOXR1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HDAC6 NLRP3 25348397 N/A physical interaction ComPPI
HDAC6 MFN2 25348397 N/A physical interaction ComPPI
HDAC6 ITCH 25348397 N/A physical interaction ComPPI
HDAC6 MAP7D3 25348397 N/A physical interaction ComPPI
HDAC6 DDX58 25348397 N/A physical interaction ComPPI
HDAC6 LPIN3 25348397 N/A physical interaction ComPPI
HDAC6 TULP2 25348397 N/A physical interaction ComPPI
HDAC6 DOCK5 25348397 N/A physical interaction ComPPI
HDAC6 SLX1A 25348397 N/A physical interaction ComPPI
HDAC6 MLH1 25348397 N/A physical interaction ComPPI
HDAC6 MRE11 25348397 N/A physical interaction ComPPI
HDAC6 RAD50 25348397 N/A physical interaction ComPPI
HDAC6 NBN 25348397 N/A physical interaction ComPPI
HDAC6 RNF31 25348397 N/A physical interaction ComPPI
HDAC6 RPS15A 25348397 N/A physical interaction ComPPI
HDAC6 RPS17 25348397 N/A physical interaction ComPPI
HDAC6 RPS3 25348397 N/A physical interaction ComPPI
HDAC6 RPS5 25348397 N/A physical interaction ComPPI
HDAC6 RPSA 25348397 N/A physical interaction ComPPI
HDAC6 HSPD1 25348397 N/A physical interaction ComPPI
HDAC6 RPL21 25348397 N/A physical interaction ComPPI
HDAC6 RPL3 25348397 N/A physical interaction ComPPI
HDAC6 ATP5F1A 25348397 N/A physical interaction ComPPI
HDAC6 DDX3X 25348397 N/A physical interaction ComPPI
HDAC6 PHGDH 25348397 N/A physical interaction ComPPI
HDAC6 EEF1A1P5 25348397 N/A physical interaction ComPPI
HDAC6 EEF2 25348397 N/A physical interaction ComPPI
HDAC6 EIF4A1 25348397 N/A physical interaction ComPPI
HDAC6 FASN 25348397 N/A physical interaction ComPPI
HDAC6 FKBP15 25348397 N/A physical interaction ComPPI
HDAC6 HNRNPR 25348397 N/A physical interaction ComPPI
HDAC6 H2BC3 25348397 N/A physical interaction ComPPI
HDAC6 MYL6 25348397 N/A physical interaction ComPPI
HDAC6 MYH9 25348397 N/A physical interaction ComPPI
HDAC6 NCL 25348397 N/A physical interaction ComPPI
HDAC6 PCMT1 25348397 N/A physical interaction ComPPI
HDAC6 FUS 25348397 N/A physical interaction ComPPI
HDAC6 STAT3 25348397 N/A physical interaction ComPPI
HDAC6 PTPA 25348397 N/A physical interaction ComPPI
HDAC6 CDK1 25348397 N/A physical interaction ComPPI
HDAC6 MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC6 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC6 FYN 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
HDAC6 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HDAC6 PSMD2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HDAC6 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
HSPA9 HDAC6 25348397 N/A physical interaction ComPPI
ETV6 HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 HDAC6 25348397 N/A physical interaction ComPPI
DDX19B HDAC6 25348397 N/A physical interaction ComPPI
CPSF1 HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PELO HDAC6 25348397 N/A physical interaction ComPPI
SLMAP HDAC6 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DDX41 HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CTTNBP2NL HDAC6 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VCP HDAC6 11689694 14525934 N/A experimental interaction detection HPRD
H2BC5 HDAC6 24234451 30021884 physical association cross-linking study IntAct
H2BC14 HDAC6 24234451 30021884 physical association cross-linking study IntAct
PKD2 HDAC6 24459142 27898060 N/A N/A OmniPath
HDAC6 CTTN 17643370 21847094 27898060 stimulant N/A OmniPath
EGFR HDAC6 20029029 20133936 24658140 25402006 27898060 inhibition N/A OmniPath
HDAC6 ELAVL1 18644987 27898060 inhibition N/A OmniPath
HDAC6 HSP90B1 19158084 27898060 stimulant N/A OmniPath
AURKA HDAC6 17604723 27898060 stimulant N/A OmniPath
MAPK3 HDAC6 24089523 27898060 stimulant N/A OmniPath
HDAC6 HSP90AA1 15916966 15937340 18266962 18591380 19158084 22367781 23703321 27898060 stimulant N/A OmniPath
HDAC6 TUBA4B 12024216 12486003 20029029 27898060 inhibition N/A OmniPath
EP300 HDAC6 12718889 15102857 19344692 22778253 23133622 27898060 inhibition N/A OmniPath
CSNK2A1 HDAC6 21486957 27898060 N/A N/A OmniPath
HDAC6 SRSF2 21157427 27898060 stimulant N/A OmniPath

Visualization










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