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GENE：KAT2A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KAT2A
FullNmae lysine acetyltransferase 2A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4201
EnsembleID ENSG00000108773
Uniprot Q92830

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KAT2A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KAT2A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KAT2A autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KAT2A GO:0000122,GO:0000123,GO:0000124,GO:0000124,GO:0001701,GO:0001756,GO:0001819,GO:0001843,GO:0003682,GO:0003713,GO:0004402,GO:0004402,GO:0005515,GO:0005615,GO:0005634,GO:0005654,GO:0005813,GO:0006094,GO:0006282,GO:0006338,GO:0006355,GO:0006357,GO:0007507,GO:0007616,GO:0010484,GO:0010484,GO:0014070,GO:0018393,GO:0019903,GO:0021537,GO:0022037,GO:0030901,GO:0031346,GO:0031647,GO:0031667,GO:0033276,GO:0033276,GO:0035264,GO:0042826,GO:0043484,GO:0043992,GO:0043993,GO:0043997,GO:0044154,GO:0045589,GO:0045721,GO:0045722,GO:0045893,GO:0045893,GO:0045944,GO:0045944,GO:0045995,GO:0046600,GO:0048144,GO:0048167,GO:0048312,GO:0050863,GO:0051302,GO:0051726,GO:0060173,GO:0061035,GO:0061733,GO:0071356,GO:0072686,GO:0090043,GO:0106077,GO:0106078,GO:0106227,GO:0106229,GO:0140297,GO:0140672,GO:0140672,GO:1903010,GO:1990090,GO:2000036,GO:2000727

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KAT2A hsa:2648 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)
KAT2A hsa:2648 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
KAT2A hsa:2648 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
KAT2A hsa:2648 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
KAT2A hsa:2648 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF1 KAT2A 10022868 23180781 physical association affinity chromatography technology,pull down InnateDB
NR3C2 KAT2A 23180781 25707758 physical association anti tag coimmunoprecipitation InnateDB
MECOM KAT2A 23180781 23858473 physical association anti tag coimmunoprecipitation InnateDB
KAT2A SMAD3 11058129 15009097 23331499 stimulation N/A SignaLink
KAT2A SMAD2 11058129 15009097 23331499 stimulation N/A SignaLink
KAT2A SMAD7 12408818 23331499 stimulation N/A SignaLink
KAT2A SMURF1 12408818 23331499 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 KAT2A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA KAT2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KAT2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 KAT2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 KAT2A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC KAT2A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB KAT2A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA KAT2A 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
KAT2A TAF4 25361965 interaction type N/A PTMCode2
TAF4 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A ELP3 25361965 interaction type N/A PTMCode2
ELP3 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TAF5L 25361965 interaction type N/A PTMCode2
TAF5L KAT2A 25361965 interaction type N/A PTMCode2
KAT2A KAT2B 25361965 interaction type N/A PTMCode2
KAT2B KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TAF6L 25361965 interaction type N/A PTMCode2
TAF6L KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TAF10 25361965 interaction type N/A PTMCode2
TAF10 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A DDB1 25361965 interaction type N/A PTMCode2
DDB1 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TADA3 25361965 interaction type N/A PTMCode2
TADA3 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TAF6 25361965 interaction type N/A PTMCode2
TAF6 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A RBPJ 25361965 interaction type N/A PTMCode2
RBPJ KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TRRAP 25361965 interaction type N/A PTMCode2
TRRAP KAT2A 25361965 interaction type N/A PTMCode2
KAT2A MAX 25361965 interaction type N/A PTMCode2
MAX KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TAF5 25361965 interaction type N/A PTMCode2
TAF5 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A POLE3 25361965 interaction type N/A PTMCode2
POLE3 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A MYC 25361965 interaction type N/A PTMCode2
MYC KAT2A 25361965 interaction type N/A PTMCode2
KAT2A TAF2 25361965 interaction type N/A PTMCode2
TAF2 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A GTF2A2 25361965 interaction type N/A PTMCode2
GTF2A2 KAT2A 25361965 interaction type N/A PTMCode2
KAT2A ATXN7 25361965 interaction type N/A PTMCode2
ATXN7 KAT2A 25361965 interaction type N/A PTMCode2
POLR2I KAT2A 25361965 interaction type N/A PTMCode2
KAT2A POLR2I 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I KAT2A 25348397 N/A physical interaction ComPPI
SGF29 KAT2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRX KAT2A 25348397 N/A physical interaction ComPPI
KRT2 KAT2A 25348397 N/A physical interaction ComPPI
LDHA KAT2A 25348397 N/A physical interaction ComPPI
TUBB KAT2A 25348397 N/A physical interaction ComPPI
TP53BP1 KAT2A 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
TAF9 KAT2A 25348397 N/A coimmunoprecipitation,physical interaction,physical interaction ComPPI
DR1 KAT2A 25348397 N/A physical interaction ComPPI
H4C1 KAT2A 25348397 N/A physical interaction ComPPI
TACC3 KAT2A 14525934 14767476 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TAF6L KAT2A 25348397 N/A physical interaction ComPPI
TAF9B KAT2A 25348397 N/A physical interaction ComPPI
SMAD1 KAT2A 25348397 N/A physical interaction ComPPI
NOTCH1 KAT2A 10747963 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKDC KAT2A 25348397 N/A physical interaction ComPPI
CREBBP KAT2A 14525934 25348397 9742083 N/A experimental interaction detection,in vitro ComPPI,HPRD
SMAD2 KAT2A 25348397 N/A physical interaction ComPPI
EP300 KAT2A 14525934 25348397 9742083 N/A experimental interaction detection,in vitro ComPPI,HPRD
SMAD3 KAT2A 25348397 N/A physical interaction ComPPI
SMAD5 KAT2A 25348397 N/A physical interaction ComPPI
CEBPB KAT2A 25348397 N/A physical interaction ComPPI
CTBP1 KAT2A 25348397 N/A physical interaction ComPPI
KAT2B KAT2A 10373431 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MED1 KAT2A 18418385 24234451 25348397 association physical interaction,biochemical ComPPI,IntAct
PPARGC1A KAT2A 25348397 N/A physical interaction ComPPI
MED24 KAT2A 18418385 24234451 25348397 association biochemical ComPPI,IntAct
SMAD9 KAT2A 25348397 N/A physical interaction ComPPI
XRCC5 KAT2A 25348397 N/A physical interaction ComPPI
E2F1 KAT2A 20972224 24234451 24502362 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TIRAP KAT2A 25348397 N/A physical interaction ComPPI
PTGES3 KAT2A 25348397 N/A physical interaction ComPPI
MYC KAT2A 12660246 14525934 25348397 N/A affinity chromatography technology,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MAPK8IP3 KAT2A 25348397 N/A physical interaction ComPPI
XRCC6 KAT2A 14525934 25348397 9488450 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NME1 KAT2A 25348397 N/A physical interaction ComPPI
SREBF1 KAT2A 25348397 N/A physical interaction ComPPI
PPARG KAT2A 25348397 N/A physical interaction ComPPI
RELA KAT2A 25348397 N/A physical interaction ComPPI
H2BC21 KAT2A 25348397 N/A physical interaction ComPPI
E2F4 KAT2A 25348397 N/A physical interaction ComPPI
EID1 KAT2A 25348397 N/A physical interaction ComPPI
AATF KAT2A 24234451 25348397 29232376 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,confocal microscopy ComPPI,IntAct
TADA3 KAT2A 10373431 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
CUL2 KAT2A 25348397 N/A physical interaction ComPPI
CDK2 KAT2A 25348397 N/A physical interaction ComPPI
CUL4A KAT2A 25348397 N/A physical interaction ComPPI
H3-4 KAT2A 25348397 N/A physical interaction ComPPI
VHL KAT2A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
H1-5 KAT2A 25348397 N/A physical interaction ComPPI
H3C15 KAT2A 25348397 N/A physical interaction ComPPI
TAF4 KAT2A 10373431 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
TAF6 KAT2A 25348397 N/A physical interaction ComPPI
MED23 KAT2A 18418385 24234451 25348397 association biochemical ComPPI,IntAct
TAF5 KAT2A 10373431 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
TRRAP KAT2A 10373431 11931763 14525934 15115762 18418385 24234451 25348397 association affinity chromatography technology,anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro,in vivo ComPPI,HPRD,IntAct
FUBP1 KAT2A 21779003 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SUPT3H KAT2A 10373431 24234451 25348397 association affinity chromatography technology,coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTL6A KAT2A 25348397 N/A physical interaction ComPPI
KAT2A TADA2A 20508642 20562830 24234451 25348397 association anti bait coimmunoprecipitation,two hybrid,physical interaction,in vitro ComPPI,IntAct
KAT2A IRF7 12374802 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
KAT2A SIRT2 12887892 14525934 25348397 N/A anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD
KAT2A TACC1 14525934 14767476 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KAT2A TACC2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
KAT2A ATXN7 15115762 24234451 25348397 association,physical association anti bait coimmunoprecipitation,molecular sieving,pull down,physical interaction,in vivo ComPPI,IntAct
KAT2A MAX 25348397 N/A coimmunoprecipitation,physical interaction,physical interaction ComPPI
KAT2A IRF1 25348397 N/A physical interaction ComPPI
KAT2A IRF2 25348397 N/A physical interaction ComPPI
KAT2A RBPJ 25348397 N/A physical interaction ComPPI
KAT2A AK6 25348397 N/A physical interaction ComPPI
KAT2A DDB1 25348397 N/A physical interaction ComPPI
KAT2A ATXN7L3 25348397 N/A physical interaction ComPPI
KAT2A USP22 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KAT2A ENY2 25348397 N/A physical interaction ComPPI
KAT2A TAF10 10373431 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
KAT2A CTNNB1 25348397 N/A physical interaction ComPPI
KAT2A HSD11B2 25348397 N/A physical interaction ComPPI
KAT2A TP53 25348397 N/A physical interaction ComPPI
KAT2A GATA2 25348397 N/A physical interaction ComPPI
KAT2A MED16 18418385 24234451 25348397 association physical interaction,biochemical ComPPI,IntAct
KAT2A MED17 18418385 24234451 25348397 association physical interaction,biochemical ComPPI,IntAct
KAT2A SUPT7L 25348397 N/A physical interaction ComPPI
KAT2A H2AX 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KAT2A TAF5L 10373431 24234451 25348397 association affinity chromatography technology,coimmunoprecipitation,physical interaction ComPPI,IntAct
KAT2A ADAT3 25348397 N/A physical interaction ComPPI
KAT2A TADA1 25348397 N/A physical interaction ComPPI
KAT2A RAE1 25348397 N/A physical interaction ComPPI
KAT2A PCBP2 25348397 N/A physical interaction ComPPI
KAT2A SF3B3 25348397 N/A physical interaction ComPPI
KAT2A HDGF 25348397 N/A physical interaction ComPPI
KAT2A PYGO2 25348397 N/A physical interaction ComPPI
KAT2A TAF3 25348397 N/A physical interaction ComPPI
KAT2A COMMD1 25348397 N/A physical interaction ComPPI
KAT2A DTL 25348397 N/A physical interaction ComPPI
KAT2A WDHD1 21725360 21987584 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct,OmniPath
KAT2A SIRT1 25348397 N/A physical interaction ComPPI
KAT2A ZNF148 25348397 N/A physical interaction ComPPI
KAT2A YEATS2 25348397 N/A physical interaction ComPPI
KAT2A MBIP 25348397 N/A physical interaction ComPPI
KAT2A MAP3K7 25348397 N/A physical interaction ComPPI
KAT2A PBX1 25348397 N/A physical interaction ComPPI
KAT2A TCF3 25348397 N/A physical interaction ComPPI
KAT2A H2AC20 25348397 N/A physical interaction ComPPI
KAT2A BATF2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KAT2A HECW2 25348397 N/A physical interaction ComPPI
KAT2A PTF1A 25348397 N/A physical interaction ComPPI
KAT2A MYB 25348397 N/A physical interaction ComPPI
KAT2A MAGEA10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KAT2A ZZZ3 20562830 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
KAT2A UBAP2L 25348397 N/A physical interaction ComPPI
KAT2A KAT14 20562830 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KAT2A SUPT20H 25348397 N/A physical interaction ComPPI
KAT2A MED12 18418385 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,biochemical ComPPI,IntAct
KAT2A XBP1 25348397 N/A physical interaction ComPPI
KAT2A PLAC1 25348397 N/A physical interaction ComPPI
KAT2A CDK4 24234451 24870244 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KAT2A TAF2 10373431 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
KAT2A MED13 18418385 24234451 25348397 association biochemical ComPPI,IntAct
KAT2A MED14 18418385 24234451 25348397 association biochemical ComPPI,IntAct
KAT2A CDK8 18418385 24234451 25348397 29568061 association,physical association anti bait coimmunoprecipitation,ion exchange chromatography,biochemical,proximity-dependent biotin identification ComPPI,IntAct
KAT2A E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
KAT2A BUB1B 24234451 24825348 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
H3C1 KAT2A 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IKZF5 KAT2A 25348397 N/A physical interaction ComPPI
WDR5 KAT2A 25348397 N/A physical interaction ComPPI
SMARCA5 KAT2A 24234451 30021884 physical association cross-linking study IntAct
ERN1 KAT2A 27898060 9113982 N/A N/A OmniPath
KAT2A SOCS1 19339690 27898060 stimulant N/A OmniPath
KAT2A H3C1 14752096 16287840 18838386 19103755 19407812 20224553 27898060 stimulant N/A OmniPath
KAT2A SMAD2 1105813 15009097 27898060 stimulant N/A OmniPath
H2AX KAT2A 20224553 27898060 stimulant N/A OmniPath
KAT2A IRF7 12374802 27898060 N/A N/A OmniPath
KAT2A SMAD3 11058129 15009097 150091 27898060 stimulant N/A OmniPath
KAT2A SMAD7 12408818 27898060 stimulant N/A OmniPath
KAT2A SMURF1 12408818 27898060 inhibition N/A OmniPath

Visualization










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