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GENE：BECN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BECN1
FullNmae beclin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1034
EnsembleID ENSG00000126581
Uniprot Q14457

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BECN1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BECN1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BECN1 entotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BECN1 entotic_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
BECN1 cuproptosis 36523779 Consistent with our expectations, the key genes for Cuproptosis and autophagy key genes, such as Atg5, Atg12, and BECN-1, were co-expressed and strongly correlated. retulator signature
BECN1 cuproptosis 35964468 Cuproptosis-related gene sets were obtained from a previous study [9] and combined with the Molecular Signature Database (MsigDB) v7.0 database (http://www.gsea-msigdb.org/gsea/msigdb/, GOBP_CELLULAR_COPPER_ION_HOMEOSTASIS, GOBP_CELLULAR_RESPONSE_TO_COPPER_ION). Cuproptosis-related gene sets obtained from Molecular Signature Database (MsigDB) v7.25 database.
BECN1 autophagy 39636430 Among these, Beclin 1 protein encoded by BECN1 gene plays a crucial role during the initiation of autophagy. retulator signature
BECN1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
BECN1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BECN1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
BECN1 GO:0000045,GO:0000045,GO:0000045,GO:0000407,GO:0000422,GO:0000423,GO:0001666,GO:0005515,GO:0005737,GO:0005739,GO:0005768,GO:0005776,GO:0005783,GO:0005789,GO:0005802,GO:0005829,GO:0005829,GO:0006622,GO:0006914,GO:0006914,GO:0006915,GO:0006968,GO:0006995,GO:0007040,GO:0007080,GO:0008285,GO:0009410,GO:0010008,GO:0010040,GO:0010288,GO:0010506,GO:0010508,GO:0010613,GO:0016236,GO:0016241,GO:0016604,GO:0019901,GO:0030425,GO:0030674,GO:0031625,GO:0032465,GO:0032473,GO:0032801,GO:0033197,GO:0034198,GO:0034271,GO:0034272,GO:0035032,GO:0035032,GO:0036092,GO:0039521,GO:0042149,GO:0042802,GO:0043066,GO:0043069,GO:0043548,GO:0043652,GO:0045022,GO:0045022,GO:0045324,GO:0045335,GO:0048666,GO:0050435,GO:0051020,GO:0051301,GO:0051607,GO:0051897,GO:0061912,GO:0065003,GO:0070301,GO:0071275,GO:0071280,GO:0071364,GO:0097352,GO:0098780,GO:1902425,GO:1902902,GO:1905672,GO:2000378,GO:2000786,GO:2001244,GO:2001244

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BECN1 hsa:8678 path:hsa04136 Autophagy - other - Homo sapiens (human)
BECN1 hsa:8678 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
BECN1 hsa:8678 path:hsa04140 Autophagy - animal - Homo sapiens (human)
BECN1 hsa:8678 path:hsa04215 Apoptosis - multiple species - Homo sapiens (human)
BECN1 hsa:8678 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
BECN1 hsa:8678 path:hsa05010 Alzheimer disease - Homo sapiens (human)
BECN1 hsa:8678 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
BECN1 hsa:8678 path:hsa05016 Huntington disease - Homo sapiens (human)
BECN1 hsa:8678 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
BECN1 hsa:8678 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
BECN1 hsa:8678 path:hsa05131 Shigellosis - Homo sapiens (human)
BECN1 hsa:8678 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BCL2 BECN1 10604474 11704864 16179260 17106237 17438366 17446862 17891140 18612260 19050071 19273585 19347031 20622903 22039431 22885520 23064052 23180781 23377657 23430059 23850759 26192618 27754749 8929532 9765397 interaction type,physical association anti tag coimmunoprecipitation,two hybrid,tandem affinity purification ACSN,InnateDB
UVRAG BECN1 10604474 10949026 11085534 11704864 12667443 16179260 16227588 17106237 17446862 17891140 18097445 18612260 18843052 19265852 22039431 22093031 22166994 22421439 22836101 22885520 23030059 23064052 23180781 23301705 23377657 23430059 23725295 23850759 24070470 26192618 27754749 28645028 8929532 9765397 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
BECN1 ATG14 17106237 17446862 18612260 19270696 22093031 22166994 22421439 22885520 23030059 23180781 23301705 23377657 23725295 24070470 26192618 27754749 28645028 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
BECN1 PIK3C3 17106237 17446862 18612260 19270696 22093031 22166994 22421439 22885520 23030059 23180781 23301705 23377657 23725295 24070470 26192618 27754749 28645028 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
NFKB1 BECN1 19289499 21725609 23178297 23572150 26192618 interaction type N/A ACSN
DAPK1 BECN1 11323415 17703233 18974095 19180116 26192618 interaction type N/A ACSN
AMBRA1 BECN1 20417604 21358617 22441670 23030059 23180781 23377657 23974797 26192618 interaction type,physical association anti tag coimmunoprecipitation,two hybrid ACSN,InnateDB
BECN1 UVRAG 18641390 18843052 19050071 19270696 23180781 physical association anti tag coimmunoprecipitation,two hybrid,isothermal titration calorimetry,pull down,tandem affinity purification InnateDB
ATG14 BECN1 18843052 19050071 19270696 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down,tandem affinity purification InnateDB
PIK3C3 BECN1 16179260 16390869 17438366 18628207 18843052 19050071 19270696 19713971 23180781 physical association anti tag coimmunoprecipitation,tandem affinity purification InnateDB
BECN1 PIK3R4 18843052 19050071 19270696 23180781 physical association anti tag coimmunoprecipitation,tandem affinity purification InnateDB
BECN1 RUBCN 19270696 23180781 physical association anti tag coimmunoprecipitation,tandem affinity purification InnateDB
BECN1 BECN1 18641390 19050071 19270696 23180781 physical association cosedimentation in solution,pull down,tandem affinity purification InnateDB
BECN1 GOPC 19837375 23180781 physical association pull down InnateDB
BECN1 PINK1 20057503 23180781 physical association anti tag coimmunoprecipitation,two hybrid,fluorescent resonance energy transfer,pull down InnateDB
ITPR1 BECN1 19325567 23180781 physical association anti tag coimmunoprecipitation InnateDB
BECN1 BCL2L1 17659302 18628207 18641390 19049976 19713971 23180781 physical association anti tag coimmunoprecipitation,fluorescence polarization spectroscopy,isothermal titration calorimetry,nuclear magnetic resonance,pull down InnateDB
BECN1 SH3GLB1 17891140 23180781 physical association anti tag coimmunoprecipitation InnateDB
BECN1 VMP1 19056683 23180781 physical association anti tag coimmunoprecipitation InnateDB
BECN1 E2F1 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
E2F4 BECN1 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
BECN1 RBL1 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBL2 BECN1 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
RB1 BECN1 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
BECN1 JUN 19060920 23180781 physical association anti tag coimmunoprecipitation InnateDB
BCL2A1 BECN1 21167304 23180781 physical association anti tag coimmunoprecipitation InnateDB
RUBCN BECN1 22423967 23180781 physical association anti tag coimmunoprecipitation InnateDB
BECN1 NLRP4 21209283 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 BECN1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF BECN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BECN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN BECN1 19060920 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 BECN1 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F2 BECN1 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F3 BECN1 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F4 BECN1 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F6 BECN1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 BECN1 19535919 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000065D58 BECN1 19535919 22157765 22395361 22473208 22743998 25416803 25712526 26463633 26488467 mrna cleavage,inhibition experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS00002152A8 BECN1 22473208 22647547 22743998 25416803 28578340 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS00003AD231 BECN1 22248718 22743998 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS00001A405B BECN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000013ABA3 BECN1 23313552 24481443 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000046CDA6 BECN1 24681041 25416803 27158405 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000005CF5F BECN1 22473208 23274497 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS000033EBB8 BECN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 BECN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 BECN1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 BECN1 25416803 26313360 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS0000170CF4 BECN1 25416803 27940575 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 BECN1 22135298 phosphorylation N/A PhosphoSite
MAPKAPK2 BECN1 22135298 phosphorylation N/A PhosphoSite
CSNK1G2 BECN1 22135298 phosphorylation N/A PhosphoSite
DAPK1 BECN1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPKAPK3 BECN1 22135298 phosphorylation N/A PhosphoSite
PTK2 BECN1 22135298 phosphorylation N/A PhosphoSite
STK4 BECN1 22135298 phosphorylation N/A PhosphoSite
DAPK3 BECN1 22135298 phosphorylation N/A PhosphoSite
EGFR BECN1 22135298 phosphorylation N/A PhosphoSite
AKT1 BECN1 22135298 phosphorylation N/A PhosphoSite
BCL2L1 BECN1 25361965 interaction type N/A PTMCode2
BECN1 BCL2L1 25361965 interaction type N/A PTMCode2
UVRAG BECN1 25361965 interaction type N/A PTMCode2
BECN1 UVRAG 25361965 interaction type N/A PTMCode2
BECN1 GOPC 25361965 interaction type N/A PTMCode2
GOPC BECN1 25361965 interaction type N/A PTMCode2
BECN1 MCL1 25361965 interaction type N/A PTMCode2
MCL1 BECN1 25361965 interaction type N/A PTMCode2
GRID2 BECN1 25361965 interaction type N/A PTMCode2
BECN1 GRID2 25361965 interaction type N/A PTMCode2
PIK3C3 BECN1 25361965 interaction type N/A PTMCode2
BECN1 PIK3C3 25361965 interaction type N/A PTMCode2
BCL2 BECN1 25361965 interaction type N/A PTMCode2
BECN1 BCL2 25361965 interaction type N/A PTMCode2
ATG3 BECN1 25361965 interaction type N/A PTMCode2
BECN1 ATG3 25361965 interaction type N/A PTMCode2
XPO1 BECN1 25361965 interaction type N/A PTMCode2
BECN1 XPO1 25361965 interaction type N/A PTMCode2
AMBRA1 BECN1 25361965 interaction type N/A PTMCode2
BECN1 AMBRA1 25361965 interaction type N/A PTMCode2
PIK3R4 BECN1 25361965 interaction type N/A PTMCode2
BECN1 PIK3R4 25361965 interaction type N/A PTMCode2
BECN1 DAPK1 25361965 interaction type N/A PTMCode2
ATG14 BECN1 25361965 interaction type N/A PTMCode2
BECN1 ATG14 25361965 interaction type N/A PTMCode2
ATG4C BECN1 25361965 interaction type N/A PTMCode2
BECN1 ATG4C 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT18 BECN1 23112296 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB39A BECN1 24234451 24349490 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
RAB39B BECN1 24234451 24349490 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
DYNLL1 BECN1 25348397 N/A physical interaction ComPPI
TRIM21 BECN1 25348397 N/A physical interaction ComPPI
YES1 BECN1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
SGF29 BECN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 BECN1 20562859 24056303 24234451 25348397 association,physical association anti tag coimmunoprecipitation,molecular sieving ComPPI,IntAct
TBC1D7 BECN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VIM BECN1 23112296 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFAIP3 BECN1 25348397 N/A physical interaction ComPPI
TRAF6 BECN1 25348397 N/A physical interaction ComPPI
LSM3 BECN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP2 BECN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOC8 BECN1 21241894 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
TAB3 BECN1 22081109 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
TUFM BECN1 25348397 N/A physical interaction ComPPI
AIM2 BECN1 22286270 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
BCL2L1 BECN1 14525934 19180116 24234451 25348397 9765397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
DAB2 BECN1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
BTK BECN1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SLAMF1 BECN1 22493499 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CASP3 BECN1 25348397 N/A physical interaction ComPPI
PRKDC BECN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIK3CG BECN1 19050071 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AR BECN1 24234451 25348397 28445460 association anti bait coimmunoprecipitation ComPPI,IntAct
FRS2 BECN1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EIF5B BECN1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RBX1 BECN1 23974797 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HERC5 BECN1 25348397 N/A physical interaction ComPPI
NRBF2 BECN1 20562859 24234451 24785657 24849286 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDKN2A BECN1 25348397 N/A physical interaction ComPPI
UBC BECN1 25348397 N/A physical interaction ComPPI
HSP90AA1 BECN1 25348397 N/A physical interaction ComPPI
HAX1 BECN1 25348397 N/A physical interaction ComPPI
RUBCN BECN1 20562859 21062745 22493499 23954414 24034250 24234451 25348397 25594178 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
HSPA1A BECN1 25348397 N/A physical interaction ComPPI
HSPA1B BECN1 25348397 N/A physical interaction ComPPI
CHAF1A BECN1 25348397 N/A physical interaction ComPPI
MCL1 BECN1 21139567 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIB1 BECN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLEC BECN1 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
HMGB1 BECN1 20819940 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RELA BECN1 25348397 N/A physical interaction ComPPI
CAMK2G BECN1 25348397 N/A physical interaction ComPPI
EXOC2 BECN1 25348397 N/A physical interaction ComPPI
EXOC4 BECN1 21241894 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALB BECN1 21241894 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
XPO1 BECN1 11309306 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
TRAF2 BECN1 25348397 N/A physical interaction ComPPI
NSF BECN1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SMC1A BECN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GFI1B BECN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CUL4A BECN1 23974797 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EGFR BECN1 24034250 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
HTT BECN1 24234451 25348397 28445460 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
RNF2 BECN1 25348397 N/A physical interaction ComPPI
SHD BECN1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ITCH BECN1 25348397 N/A physical interaction ComPPI
SMC3 BECN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPKAPK2 BECN1 25348397 N/A physical interaction ComPPI
TSC1 BECN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP63 BECN1 19050071 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ING4 BECN1 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
ATXN3 BECN1 25348397 N/A anti bait coimmunoprecipitation ComPPI
BAK1 BECN1 17446862 24234451 25348397 physical association fluorescence polarization spectroscopy ComPPI,IntAct
USP33 BECN1 25348397 N/A physical interaction ComPPI
F7 BECN1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PYCARD BECN1 22286270 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MEFV BECN1 25348397 N/A physical interaction ComPPI
BCL2 BECN1 14525934 17446862 19050071 19180116 19959994 21139567 21358617 23541952 23954414 24034250 24234451 24472739 25348397 29849149 9765397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,cosedimentation through density gradient,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
TAB2 BECN1 22081109 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
PRKN BECN1 23737459 24386307 24879156 25348397 27898060 N/A physical interaction ComPPI,OmniPath
NEDD4 BECN1 25348397 N/A physical interaction ComPPI
BECN1 GOPC 12372286 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
BECN1 AMBRA1 14525934 17589504 20562859 21358617 23954414 23974797 24234451 25348397 25438055 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
BECN1 PIK3C3 19050071 20562859 23316280 23332761 23364696 23954414 24034250 24056303 24234451 24472739 24785657 25348397 25490155 25594178 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,electron microscopy,molecular sieving,physical interaction ComPPI,IntAct
BECN1 PIK3R4 19050071 20562859 24234451 25348397 25490155 26496610 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction ComPPI,IntAct
BECN1 SLC27A4 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 UVRAG 19050071 20562859 21597469 22081109 22493499 23954414 24034250 24056303 24234451 25348397 25490155 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,electron microscopy,molecular sieving,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BECN1 DZIP3 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 PTOV1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 ATG14 19050071 20562859 21062745 22081109 22493499 23112296 23332761 23954414 24034250 24234451 25348397 25490155 25594178 26496610 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,electron microscopy,molecular sieving,pull down,physical interaction,two hybrid array,phosphotransferase assay,two hybrid prey pooling approach ComPPI,IntAct
BECN1 TRABD 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 GSPT1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 AFG3L2 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 SEH1L 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 RUBCNL 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 ZWINT 20562859 22081109 23478334 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
BECN1 HSP90AA2P 25348397 N/A physical interaction ComPPI
BECN1 S100A8 25348397 N/A physical interaction ComPPI
BECN1 WASHC1 23974797 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
BECN1 ATG3 25348397 N/A physical interaction ComPPI
BECN1 ULK1 25348397 N/A physical interaction ComPPI
BECN1 BRCA1 25348397 N/A physical interaction ComPPI
BECN1 DACT1 25348397 N/A physical interaction ComPPI
BECN1 CDKN2A 25348397 N/A physical interaction ComPPI
BECN1 DAPK1 19180116 24234451 25348397 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,protein kinase assay ComPPI,IntAct
BECN1 DYNC1I1 25348397 N/A physical interaction ComPPI
BECN1 DDB1 23974797 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 USP18 25348397 N/A physical interaction ComPPI
BECN1 TCOF1 20562859 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 NLRP2 25348397 N/A physical interaction ComPPI
BECN1 NLRP5 25348397 N/A physical interaction ComPPI
BECN1 MDN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 NGDN 25348397 N/A physical interaction ComPPI
BECN1 RNF216 25348397 N/A physical interaction ComPPI
BECN1 BIRC5 20638385 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
BECN1 IRGM 25348397 N/A physical interaction ComPPI
BECN1 TP53 25348397 N/A physical interaction ComPPI
BECN1 MAPKAPK3 25348397 N/A physical interaction ComPPI
BECN1 TRIM16 25348397 N/A physical interaction ComPPI
BECN1 SPHK1 25348397 N/A physical interaction ComPPI
BECN1 WDR81 25348397 N/A physical interaction ComPPI
BECN1 WDR91 25348397 N/A physical interaction ComPPI
BECN1 GLIPR2 23364696 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 AKT1 23112296 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 FAM120A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 USP10 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 IMMT 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 SH3GLB2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 GYS1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 MYL12B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 ATG12 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 WDR82 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 MYH9 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 MYH10 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 HSD17B12 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 ATG5 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 SRP72 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 MYL6 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 TECPR1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 ATG16L1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 WIPI1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 DSP 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
BECN1 GAS7 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
BECN1 SNX4 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
BECN1 GSE1 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
BECN1 TNRC18 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
BECN1 VMP1 23316280 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
BECN1 NXF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BECN1 ATN1 24234451 25348397 28445460 association anti bait coimmunoprecipitation ComPPI,IntAct
BECN1 BECN1 20562859 24034250 24234451 association,physical association anti tag coimmunoprecipitation IntAct
BECN1 ITPR1 19325567 27898060 N/A N/A OmniPath
BECN1 BCL2A1 21167304 27898060 N/A N/A OmniPath
BECN1 NLRP4 21209283 27898060 N/A N/A OmniPath
EGFR BECN1 24034250 27898060 N/A N/A OmniPath
TNFAIP3 BECN1 20501938 27898060 inhibition N/A OmniPath
MAPKAPK3 BECN1 23878393 25693418 27898060 N/A N/A OmniPath
RUBCN BECN1 19270693 19270696 20562859 22423967 22493499 24980960 25594178 25891078 26496610 27898060 inhibition N/A OmniPath
BCL2L1 BECN1 17337444 17446862 17659302 18628207 18641390 19049976 19180116 19713971 22219388 24115198 27898060 9765397 inhibition,stimulant N/A OmniPath
BECN1 BCL2L1 17659302 18628207 18641390 19049976 19180116 19713971 22219388 24115198 27898060 9765397 N/A N/A OmniPath
VMP1 BECN1 17940279 19056683 23316280 27898060 stimulant N/A OmniPath
ATG14 BECN1 18843052 19050071 19223761 19270693 19270696 20562859 20711182 21062745 22081109 23112296 23878393 23954414 24034250 24980960 25891078 26496610 27898060 stimulant N/A OmniPath
BCL2 BECN1 16179260 16799551 17438366 17446862 17643073 18281291 18570871 18641390 18772134 19050071 19273585 19347031 19959994 20010695 20622903 20711182 20889974 21358617 21543763 21971985 22622204 23168911 23316280 23479509 23504944 23541952 23564079 23954414 24034250 24472739 25891078 25984893 27898060 9765397 inhibition N/A OmniPath
ULK1 BECN1 16940348 17595159 21241894 23685627 25891078 27898060 stimulant N/A OmniPath
TRAF6 BECN1 20501938 27898060 stimulant N/A OmniPath
TP63 BECN1 22356768 27898060 N/A N/A OmniPath
AKT1 BECN1 23112296 27898060 N/A N/A OmniPath
SH3GLB1 BECN1 17891140 21311563 27898060 stimulant N/A OmniPath
STK4 BECN1 24141421 27898060 N/A N/A OmniPath
BECN1 AMBRA1 17589504 20417604 20562859 20711182 20921139 21358617 23954414 23974797 24587252 25499913 27898060 stimulant N/A OmniPath
AMBRA1 BECN1 17589504 20417604 20562859 20711182 20921139 21358617 23954414 23974797 24587252 25499913 27898060 stimulant N/A OmniPath
XBP1 BECN1 23184933 27898060 N/A N/A OmniPath
MCL1 BECN1 21139567 21353614 22219388 27898060 inhibition N/A OmniPath
BECN1 PIK3C3 16179260 16390869 17438366 18628207 18843052 19050071 19172397 19270696 19379691 19713971 20562859 20711182 21936852 23315026 23878393 23974797 24472739 24980959 24980960 25825496 25906440 26496610 27898060 stimulant N/A OmniPath
RELA BECN1 19289499 27898060 stimulant N/A OmniPath
HMGB1 BECN1 20819940 27898060 inhibition N/A OmniPath
BECN1 HMGB1 20819940 27898060 stimulant N/A OmniPath
PINK1 BECN1 20057503 27898060 stimulant N/A OmniPath
DAPK1 BECN1 19180116 19395874 27898060 inhibition,stimulant N/A OmniPath
MAPK8 BECN1 19060920 27898060 N/A N/A OmniPath
UVRAG BECN1 16799551 17106237 18641390 18843052 19050071 19172397 19270696 20562859 21311563 21597469 22081109 23878393 23954414 24034250 26496610 27898060 inhibition,stimulant N/A OmniPath
BECN1 PIK3R4 18843052 18957027 19050071 19270696 20562859 20711182 23878393 26496610 27898060 stimulant N/A OmniPath
GOPC BECN1 12372286 19837375 21311563 27898060 stimulant N/A OmniPath
CSNK1G2 BECN1 26008601 27898060 N/A N/A OmniPath

Visualization










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