Gene Information gene info

  1. Home

GENE：FOXO1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FOXO1
FullNmae forkhead box O1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3819
EnsembleID ENSG00000150907
Uniprot Q12778

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FOXO1 autophagy 32197645 NAC and the FOXO1 inhibitor AS1842856 rescued the apoptosis and autophagy induced by cholesterol. retulator signature
FOXO1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FOXO1 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0001228,GO:0001228,GO:0001568,GO:0001659,GO:0001678,GO:0003676,GO:0003682,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0006357,GO:0006473,GO:0006914,GO:0006915,GO:0006974,GO:0008013,GO:0008286,GO:0008286,GO:0009267,GO:0009267,GO:0010467,GO:0010508,GO:0031490,GO:0031625,GO:0032869,GO:0032873,GO:0034599,GO:0043065,GO:0043066,GO:0043565,GO:0045444,GO:0045599,GO:0045722,GO:0045732,GO:0045892,GO:0045893,GO:0045944,GO:0045944,GO:0046676,GO:0051721,GO:0060070,GO:0070417,GO:0070542,GO:0071455,GO:0071732,GO:0090090,GO:0097009,GO:0097150,GO:1903243,GO:1990841,GO:2000177,GO:2000377

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FOXO1 hsa:2308 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04218 Cellular senescence - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04922 Glucagon signaling pathway - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04931 Insulin resistance - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa05131 Shigellosis - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa05200 Pathways in cancer - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
FOXO1 hsa:2308 path:hsa05215 Prostate cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FOXO1 PPARGC1A 10364186 15668399 16122419 19449109 25464856 26192618 association N/A ACSN
FOXO1 PDCD1 15668399 19449109 25464856 26192618 interaction type N/A ACSN
FOXO1 ALAS1 10364186 15668399 16122419 19449109 25464856 26192618 interaction type N/A ACSN
CKS1B FOXO1 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080 26192618 interaction type N/A ACSN
CUL1 FOXO1 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080 26192618 interaction type N/A ACSN
SKP1 FOXO1 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080 26192618 interaction type N/A ACSN
SKP2 FOXO1 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080 26192618 interaction type N/A ACSN
DYRK1A FOXO1 11980723 12138125 16511445 19685005 26192618 interaction type N/A ACSN
FOXO1 FSHR 17030088 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 FOXO1 17077083 23180781 physical association anti tag coimmunoprecipitation InnateDB
AKT1 FOXO1 10358014 10358075 11237865 13679577 18988627 23180781 23331499 phosphorylation reaction,stimulation in-gel kinase assay,protein kinase assay InnateDB,SignaLink,SignaLink
YWHAG FOXO1 11237865 23180781 physical association anti tag coimmunoprecipitation InnateDB
FOXO1 YWHAZ 11237865 23180781 physical association anti tag coimmunoprecipitation InnateDB
TXNIP FOXO1 23180781 24112473 physical association anti tag coimmunoprecipitation InnateDB
FOXO1 PDGFRA 22411791 23180781 physical association anti tag coimmunoprecipitation InnateDB
FOXO1 FOXO1 12913110 26467481 up-regulates quantity by expression,transcriptional regulation N/A Signor
SGK1 FOXO1 17640988 23331499 stimulation N/A SignaLink
CTNNB1 FOXO1 15905404 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR FOXO1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 FOXO1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FOXO1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FOXO1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 FOXO1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 FOXO1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 FOXO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXC1 FOXO1 17993506 21837767 trascriptional regulation,stimulation inferred by curator TFlink
KLF5 FOXO1 21487104 trascriptional regulation,stimulation inferred by curator TFlink
PARP1 FOXO1 19281796 trascriptional regulation,stimulation inferred by curator TFlink
TSC22D3 FOXO1 20018851 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 FOXO1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001CC379 FOXO1 19574223 \N rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000345DEB FOXO1 20028871 rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry miRSponge
URS000021D7C8 FOXO1 20028871 rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry miRSponge
URS00000B7E30 FOXO1 22569260 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay miRSponge
URS00001B341F FOXO1 19574223 20028871 22213032 \N rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS000016FF9C FOXO1 19574223 20028871 \N rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS00001CC379 FOXO1 18927107 19574223 22012620 24865442 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS00001B341F FOXO1 18927107 19574223 20028871 22213032 24746199 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS000016FF9C FOXO1 18927107 19574223 20028871 22012620 23807165 25369914 25416803 26617698 mrna cleavage,inhibition array technology,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS000021D7C8 FOXO1 20028871 20371350 21572407 25416803 mrna cleavage,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,clip TarBase
URS0000345DEB FOXO1 20028871 22012620 24368418 25416803 mrna cleavage,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00000B7E30 FOXO1 22569260 24324762 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 FOXO1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 FOXO1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000600E6 FOXO1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000028BB8 FOXO1 23622248 24014289 25416803 26298723 27556448 mrna cleavage,inhibition experimental interaction detection,nucleotide sequence identification,western blot,quantitative reverse transcription pcr,clash,miRNA interference luciferase reporter assay TarBase
URS0000171CD1 FOXO1 23622248 24862853 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clash,miRNA interference luciferase reporter assay TarBase
URS000041CB9C FOXO1 24862853 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004900F1 FOXO1 23029264 23721824 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000008F0CF FOXO1 24374340 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000031E12 FOXO1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 FOXO1 24746199 25416803 26452502 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry TarBase
URS00001383CF FOXO1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 FOXO1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 FOXO1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE FOXO1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 FOXO1 20371350 21572407 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF FOXO1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 FOXO1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 FOXO1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003677B2 FOXO1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D FOXO1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B FOXO1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 FOXO1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 FOXO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC FOXO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB FOXO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000001C659 FOXO1 25416803 26617737 mrna cleavage,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay TarBase
URS0000171525 FOXO1 25416803 27917915 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000153377 FOXO1 25416803 27746366 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000003FD55 FOXO1 25416803 25695055 mrna cleavage,inhibition western blot TarBase
URS00000F31F4 FOXO1 25416803 28485164 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000009262D FOXO1 25416803 25909227 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 FOXO1 22135298 phosphorylation N/A PhosphoSite
CDK1 FOXO1 22135298 phosphorylation N/A PhosphoSite
CDK2 FOXO1 22135298 phosphorylation N/A PhosphoSite
NLK FOXO1 22135298 phosphorylation N/A PhosphoSite
DYRK1A FOXO1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK4 FOXO1 22135298 phosphorylation N/A PhosphoSite
CDK5 FOXO1 22135298 phosphorylation N/A PhosphoSite
CSNK1A1 FOXO1 22135298 phosphorylation N/A PhosphoSite
AKT1 FOXO1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
G6PC1 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 G6PC1 25361965 interaction type N/A PTMCode2
YWHAG FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 YWHAG 25361965 interaction type N/A PTMCode2
GSK3B FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 GSK3B 25361965 interaction type N/A PTMCode2
BCL2L11 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 BCL2L11 25361965 interaction type N/A PTMCode2
CEBPB FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 CEBPB 25361965 interaction type N/A PTMCode2
CSNK1G1 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 CSNK1G1 25361965 interaction type N/A PTMCode2
TP53 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 TP53 25361965 interaction type N/A PTMCode2
AR FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 AR 25361965 interaction type N/A PTMCode2
HNF4A FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 HNF4A 25361965 interaction type N/A PTMCode2
HOXA11 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 HOXA11 25361965 interaction type N/A PTMCode2
SMAD4 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 SMAD4 25361965 interaction type N/A PTMCode2
YWHAB FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 YWHAB 25361965 interaction type N/A PTMCode2
SKP2 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 SKP2 25361965 interaction type N/A PTMCode2
FOXO1 AKT1 25361965 interaction type N/A PTMCode2
FOXO1 DYRK1A 25361965 interaction type N/A PTMCode2
PML FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 PML 25361965 interaction type N/A PTMCode2
SIRT1 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 SIRT1 25361965 interaction type N/A PTMCode2
HOXA10 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 HOXA10 25361965 interaction type N/A PTMCode2
CTNNB1 FOXO1 25361965 interaction type N/A PTMCode2
FOXO1 CTNNB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MORF4L2 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RARA FOXO1 11353774 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CDKN1A FOXO1 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
SET FOXO1 24234451 24983498 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct,OmniPath
YWHAG FOXO1 11237865 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMAD4 FOXO1 14525934 15084259 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PITX1 FOXO1 25348397 N/A physical interaction ComPPI
NLK FOXO1 25348397 N/A physical interaction ComPPI
PAK1 FOXO1 25348397 N/A in vivo ComPPI
FOXG1 FOXO1 14525934 15084259 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SRC FOXO1 10973497 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RB1 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AR FOXO1 12482965 14525934 17202144 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CREBBP FOXO1 10973497 14525934 15220471 24234451 25348397 25609649 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
NCOA1 FOXO1 25348397 N/A physical interaction ComPPI
EP300 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SMAD3 FOXO1 14525934 15084259 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
COP1 FOXO1 25348397 N/A physical interaction ComPPI
FHL2 FOXO1 14525934 15692560 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,imaging technique,in vitro ComPPI,HPRD,IntAct
CEBPB FOXO1 11893744 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKACA FOXO1 25348397 N/A physical interaction ComPPI
GSK3B FOXO1 11980723 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
THRB FOXO1 11353774 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
YWHAZ FOXO1 11237865 14525934 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PIK3R3 FOXO1 25348397 N/A physical interaction ComPPI
IRF3 FOXO1 25348397 N/A physical interaction ComPPI
TNS2 FOXO1 25348397 N/A physical interaction ComPPI
SNX17 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PARP1 FOXO1 25348397 N/A physical interaction ComPPI
SMARCA4 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PPARG FOXO1 12966085 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
TSC2 FOXO1 25348397 N/A physical interaction ComPPI
ATM FOXO1 25348397 N/A physical interaction ComPPI
XPO1 FOXO1 25348397 N/A physical interaction ComPPI
YWHAQ FOXO1 25348397 N/A physical interaction ComPPI
MDM2 FOXO1 25348397 N/A physical interaction ComPPI
FOXO4 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SKP2 FOXO1 25348397 N/A physical interaction ComPPI
CCNB1 FOXO1 18408765 24234451 25241761 25348397 phosphorylation reaction,physical association physical interaction,protein kinase assay,proximity ligation assay ComPPI,IntAct
CTNNB1 FOXO1 14525934 15905404 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SIRT2 FOXO1 25348397 N/A physical interaction ComPPI
HNF4A FOXO1 25348397 N/A physical interaction,in vitro ComPPI
STK4 FOXO1 25348397 N/A physical interaction,protein kinase assay ComPPI
SIRT1 FOXO1 14525934 15220471 15692560 18235501 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
SETD7 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DLX5 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LRPPRC FOXO1 25348397 N/A physical interaction ComPPI
FSHR FOXO1 25348397 N/A physical interaction ComPPI
RECQL FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ESR1 FOXO1 11353774 11435445 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SATB1 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AKT1 FOXO1 10358014 14525934 18786403 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
STUB1 FOXO1 25348397 N/A physical interaction ComPPI
PML FOXO1 25348397 N/A physical interaction ComPPI
CRY1 FOXO1 25348397 N/A physical interaction ComPPI
ATG7 FOXO1 25348397 N/A physical interaction ComPPI
DYRK1A FOXO1 11311120 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CSNK1G1 FOXO1 25348397 N/A in vivo ComPPI
SATB2 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CUX1 FOXO1 25348397 N/A physical interaction ComPPI
FOXO1 HOXA5 12163409 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FOXO1 HOXA10 12493691 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FOXO1 G6PC1 25348397 N/A in vitro ComPPI
FOXO1 HOXA11 25348397 N/A physical interaction ComPPI
FOXO1 MST1 25348397 N/A physical interaction ComPPI
FOXO1 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXO1 HOXD13 25348397 N/A physical interaction ComPPI
FOXO1 DNAJC9 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXO1 SIRT7 25348397 N/A physical interaction ComPPI
FOXO1 CDK1 18408765 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,protein kinase assay ComPPI,IntAct
FOXO1 HOXC13 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
FOXO1 FOXO6 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
FOXO1 FOXO1 24234451 25609649 association tandem affinity purification IntAct
KLF2 FOXO1 18713968 24234451 association chromatin immunoprecipitation assay IntAct
NCL FOXO1 24234451 30021884 physical association cross-linking study IntAct
PPARA FOXO1 16985262 18391971 27898060 inhibition N/A OmniPath
CTNNB1 FOXO1 15905404 17254970 27898060 stimulant N/A OmniPath
CSNK1A1 FOXO1 11980723 19188143 27898060 inhibition,stimulant N/A OmniPath
SIRT2 FOXO1 15220471 17684529 20543840 24419059 27898060 inhibition,stimulant N/A OmniPath
FOXO1 ATG7 20543840 22622204 23640897 27898060 stimulant N/A OmniPath
FOXO1 IGFBP1 18391971 18985696 27898060 stimulant N/A OmniPath
INS FOXO1 10358076 27898060 inhibition N/A OmniPath
FOXO1 ATG14 22992773 27898060 N/A N/A OmniPath
NR1I3 FOXO1 18391971 27898060 inhibition N/A OmniPath
FOXO1 NCOR2 18391971 27898060 inhibition N/A OmniPath
CDK2 FOXO1 17038621 17522590 27898060 inhibition,stimulant N/A OmniPath
PGR FOXO1 18391971 27898060 stimulant N/A OmniPath
SIRT1 FOXO1 14976264 14980222 15220471 15692560 15788402 16154098 18235501 22013015 27898060 inhibition,stimulant N/A OmniPath
ESR1 FOXO1 11353774 11435445 18391971 22266855 27898060 inhibition N/A OmniPath
SKP2 FOXO1 15668399 17522590 17646672 19686743 27898060 inhibition,stimulant N/A OmniPath
AKT1 FOXO1 10102273 10358014 10358075 10358076 11030146 11237865 11251083 11980723 12228231 1367958 16076959 16341064 16670089 16670091 17254970 17962350 18316359 18423396 18786403 18951090 18985696 20041807 21440011 21798082 25241761 27898060 2984676 2987962 inhibition,stimulant N/A OmniPath
STK4 FOXO1 18394876 18786403 21245099 22898666 27898060 stimulant N/A OmniPath
NR1I2 FOXO1 17684529 27898060 stimulant N/A OmniPath
FOXO1 NR1I2 17684529 27898060 stimulant N/A OmniPath
CEBPB FOXO1 11893744 18391971 27898060 stimulant N/A OmniPath
FOXO1 KLF4 18375530 27898060 stimulant N/A OmniPath
FOXO1 MAML1 18391971 27898060 stimulant N/A OmniPath
FOXG1 FOXO1 15084259 18391971 27898060 inhibition N/A OmniPath
FOXO1 BCL2L11 12913110 27898060 stimulant N/A OmniPath
CDK1 FOXO1 18356527 18408765 27898060 inhibition,stimulant N/A OmniPath
FOXO1 NOXA1 21245099 27898060 stimulant N/A OmniPath
AR FOXO1 12482965 17202144 18391971 27898060 inhibition,stimulant N/A OmniPath
FOXO1 AR 12482965 17202144 18391971 27898060 inhibition,stimulant N/A OmniPath
FOXO1 TRIM63 18612045 27898060 stimulant N/A OmniPath
TSC2 FOXO1 17077083 27898060 N/A N/A OmniPath
PAK1 FOXO1 10358014 12560069 27898060 N/A N/A OmniPath
SGK1 FOXO1 11980723 17640988 17684529 27898060 inhibition,stimulant N/A OmniPath
HOXA10 FOXO1 12493691 18391971 27898060 stimulant N/A OmniPath
FOXO1 PPARG 12966085 17317207 27898060 inhibition N/A OmniPath
USP7 FOXO1 17522590 27898060 inhibition,stimulant N/A OmniPath
AKT2 FOXO1 10377430 27898060 inhibition N/A OmniPath
GSK3B FOXO1 11980723 25241761 27898060 N/A N/A OmniPath
FOXO1 G6PC1 11467835 11672436 16840535 27898060 stimulant N/A OmniPath
DUSP6 FOXO1 22521266 27898060 stimulant N/A OmniPath
SMAD3 FOXO1 15084259 18391971 27898060 stimulant N/A OmniPath
FOXO1 PDGFRA 22411791 27898060 N/A N/A OmniPath
FGFR3 FOXO1 10358014 11311120 11410590 27898060 N/A N/A OmniPath
YWHAH FOXO1 14690436 27898060 inhibition N/A OmniPath
PRKAA1 FOXO1 17900900 27898060 stimulant N/A OmniPath
DYRK1A FOXO1 10358014 10358075 11311120 11410590 11980723 19188143 27898060 inhibition,stimulant N/A OmniPath
PKN1 FOXO1 12560069 27898060 inhibition N/A OmniPath
CSNK1G1 FOXO1 11980723 27898060 stimulant N/A OmniPath

Visualization










  Return