Gene Information gene info

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GENE：MTDH

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTDH
FullNmae metadherin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29608
EnsembleID ENSG00000147649
Uniprot Q86UE4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTDH ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTDH autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTDH autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MTDH GO:0000122,GO:0001650,GO:0003712,GO:0003713,GO:0003723,GO:0003725,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005783,GO:0005789,GO:0005923,GO:0006357,GO:0010508,GO:0016324,GO:0016604,GO:0031663,GO:0031965,GO:0043066,GO:0043123,GO:0045766,GO:0045893,GO:0046581,GO:0048471,GO:0051059,GO:0051059,GO:0051092,GO:0051897,GO:0061629

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MTDH 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MTDH 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MTDH 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MTDH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC MTDH 17088530 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000204177 MTDH 22967897 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000ED600 MTDH 22508479 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000ED600 MTDH 20215506 22508479 22752059 25416803 25944465 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000204177 MTDH 22967897 25266957 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F31F4 MTDH 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 MTDH 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000B59A2 MTDH 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 MTDH 18668040 22473208 23851509 25416803 26884832 mrna cleavage,inhibition experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay TarBase
URS000023BE29 MTDH 23592263 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00004F859B MTDH 25416803 25432696 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000027352D MTDH 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 MTDH 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 MTDH 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 MTDH 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 MTDH 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F MTDH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MTDH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 MTDH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 MTDH 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 MTDH 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 MTDH 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 MTDH 24144591 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00002E0524 MTDH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000553F51 MTDH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 MTDH 21572407 23446348 23592263 24398324 25416803 27602115 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS000061E50F MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004C689A MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000009265 MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000058863C MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000055BBE5 MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD MTDH 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003CF1AD MTDH 25416803 27229534 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000027080C MTDH 25416803 26176806 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004F4657 MTDH 25416803 25428378 27765924 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay TarBase
URS0000148B91 MTDH 25416803 28112756 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000096022 MTDH 25323629 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000060B2B MTDH 25416803 28184926 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004BC299 MTDH 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB14 MTDH 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MTDH RELA 25361965 interaction type N/A PTMCode2
RELA MTDH 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF1B MTDH 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LMNA MTDH 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SND1 MTDH 24234451 24981741 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
JUN MTDH 24234451 25348397 25609649 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CREBBP MTDH 18316612 24234451 25348397 26141861 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
EP300 MTDH 25348397 N/A physical interaction ComPPI
CUL3 MTDH 25348397 N/A physical interaction ComPPI
NTRK1 MTDH 25348397 N/A physical interaction ComPPI
CANX MTDH 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BTRC MTDH 25348397 N/A physical interaction ComPPI
PLEC MTDH 25348397 N/A physical interaction ComPPI
CSNK2A1 MTDH 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
RELA MTDH 18316612 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB16 MTDH 25348397 N/A physical interaction ComPPI
TOPORS MTDH 24529480 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RNF2 MTDH 25348397 N/A physical interaction ComPPI
GABARAP MTDH 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ACTL6A MTDH 25348397 N/A physical interaction ComPPI
SIRT2 MTDH 25348397 N/A physical interaction ComPPI
HIF1AN MTDH 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
MME MTDH 17342744 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC4 MTDH 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ESR1 MTDH 21182205 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
TARDBP MTDH 25348397 N/A physical interaction ComPPI
AGO2 MTDH 24234451 24981741 25348397 association,physical association anti tag coimmunoprecipitation ComPPI,IntAct
MTUS2 MTDH 25348397 N/A physical interaction ComPPI
LYAR MTDH 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PLGRKT MTDH 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TMEM216 MTDH 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LAMP1 MTDH 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
OTUD6B MTDH 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZYG11B MTDH 25348397 N/A physical interaction ComPPI
MTDH CCDC8 25348397 N/A physical interaction ComPPI
MTDH NR2E1 25348397 N/A physical interaction ComPPI
MTDH TMEM237 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MTDH SNN 25348397 N/A physical interaction ComPPI
MTDH MNS1 24234451 30021884 physical association cross-linking study IntAct

Visualization










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