GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
TRIM65
FullNmae
tripartite motif containing 65
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:27316
EnsembleID
ENSG00000141569
Uniprot
Q6PJ69
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
TRIM65
autophagy
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
TRIM65
autophagy
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
TRIM65
GO:0001934,GO:0005654,GO:0005737,GO:0005829,GO:0008270,GO:0010508,GO:0010508,GO:0016567,GO:0032461,GO:0032727,GO:0032728,GO:0050728,GO:0060337,GO:0061630,GO:0140374
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
SRPK1
TRIM65
23180781
23602568
phosphorylation reaction
protein kinase assay
InnateDB
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
TRIM65
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
TRIM65
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
TRIM65
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
TRIM65
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
TRIM65
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
TRIM65
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00003380CC
TRIM65
17612493
25416803
mrna cleavage,inhibition
array technology
TarBase
URS000003ABC4
TRIM65
20371350
25416803
mrna cleavage,inhibition
nucleotide sequence identification
TarBase
URS00005651EE
TRIM65
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000005481D
TRIM65
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00001597DC
TRIM65
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00000DDD35
TRIM65
23622248
25416803
27292025
mrna cleavage,inhibition
clip,clash
TarBase
URS0000355E82
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075A760
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002152A8
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00004D84DB
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001C770D
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000006372A
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000052EA98
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000EEE35
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00004CCA62
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000183BED
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001CC864
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000411752
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000753AD
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000011DF
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000041E780
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000013ABA3
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003FBC84
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000043C1C3
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000486E0B
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000047A67D
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000451A1
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003E226A
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00005D12AC
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000038446A
TRIM65
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000039E1E1
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00000600E6
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000016FD1A
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00002075FA
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000021D7C8
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000042E1F
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00002B3783
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000070CD2
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000346991
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000027080C
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000041E949
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000508C13
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000298BA3
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000021D08
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000075AB14
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000075D814
TRIM65
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
MKRN3
TRIM65
22493164
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
RHOA
TRIM65
24234451
25348397
27829229
physical association
coimmunoprecipitation
ComPPI,IntAct
AXIN1
TRIM65
25348397
N/A
physical interaction
ComPPI
SRPK1
TRIM65
23602568
24234451
25348397
phosphorylation reaction
physical interaction,protein kinase assay
ComPPI,IntAct
ALOX5
TRIM65
25348397
N/A
physical interaction
ComPPI
ELAVL1
TRIM65
25348397
N/A
physical interaction
ComPPI
TES
TRIM65
25348397
N/A
physical interaction
ComPPI
P4HA2
TRIM65
25348397
N/A
physical interaction
ComPPI
ANAPC11
TRIM65
22493164
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
UBE2Z
TRIM65
19549727
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
RBCK1
TRIM65
22493164
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
MARCHF7
TRIM65
22493164
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
GATD1
TRIM65
25348397
N/A
physical interaction
ComPPI
TNRC6B
TRIM65
25348397
N/A
physical interaction
ComPPI
TP53
TRIM65
25348397
N/A
physical interaction
ComPPI
UBE3A
TRIM65
21900206
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
TNRC6A
TRIM65
25348397
N/A
physical interaction
ComPPI
UBE2U
TRIM65
19690564
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
TRIM65
ALDH3B1
25348397
N/A
physical interaction
ComPPI
TRIM65
ARHGAP25
25348397
N/A
physical interaction
ComPPI
TRIM65
CCNJL
25348397
N/A
physical interaction
ComPPI
TRIM65
CRYL1
25348397
N/A
physical interaction
ComPPI
TRIM65
SNX21
25348397
N/A
physical interaction
ComPPI
TRIM65
DOCK5
25348397
N/A
physical interaction
ComPPI
Visualization