Gene Information gene info

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GENE：CDK5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDK5
FullNmae cyclin dependent kinase 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1774
EnsembleID ENSG00000164885
Uniprot Q00535

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDK5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDK5 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDK5 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CDK5 GO:0000083,GO:0000226,GO:0000307,GO:0000307,GO:0001764,GO:0001963,GO:0002039,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004674,GO:0004693,GO:0004693,GO:0005176,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005874,GO:0005886,GO:0006468,GO:0006468,GO:0006886,GO:0007160,GO:0007268,GO:0007409,GO:0007416,GO:0007519,GO:0008045,GO:0008542,GO:0014044,GO:0014069,GO:0016020,GO:0016079,GO:0016241,GO:0016301,GO:0016310,GO:0016533,GO:0016533,GO:0018105,GO:0018105,GO:0018107,GO:0019233,GO:0021697,GO:0021766,GO:0021819,GO:0021954,GO:0022038,GO:0030027,GO:0030054,GO:0030175,GO:0030182,GO:0030182,GO:0030334,GO:0030424,GO:0030425,GO:0030426,GO:0030517,GO:0030549,GO:0031175,GO:0031175,GO:0031397,GO:0031594,GO:0031914,GO:0032801,GO:0035249,GO:0035418,GO:0042981,GO:0043005,GO:0043025,GO:0043113,GO:0043125,GO:0043204,GO:0043525,GO:0045786,GO:0045861,GO:0045892,GO:0045956,GO:0046826,GO:0048148,GO:0048156,GO:0048167,GO:0048167,GO:0048488,GO:0048489,GO:0048511,GO:0048675,GO:0048709,GO:0048813,GO:0050321,GO:0050321,GO:0051301,GO:0051402,GO:0051402,GO:0051726,GO:0051879,GO:0051966,GO:0060079,GO:0061001,GO:0070509,GO:0090314,GO:0098793,GO:0106310,GO:1903076,GO:1903421,GO:1904646

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CDK5 hsa:1020 path:hsa04360 Axon guidance - Homo sapiens (human)
CDK5 hsa:1020 path:hsa05010 Alzheimer disease - Homo sapiens (human)
CDK5 hsa:1020 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
CDK5 hsa:1020 path:hsa05030 Cocaine addiction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DAB1 CDK5 20005715 interaction type N/A PSP
PPP1R1B CDK5 20005715 interaction type N/A PSP
PPP1R2 CDK5 20005715 interaction type N/A PSP
DAB1 CDK5 20005715 20005715 N/A N/A SignaLink
PPP1R1B CDK5 20005715 20005715 N/A N/A SignaLink
PPP1R2 CDK5 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR CDK5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CDK5 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CDK5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF CDK5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CDK5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 CDK5 N/A trascriptional regulation,stimulation inferred by curator TFlink
FOS CDK5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 CDK5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
CDK5 PXN 22135298 phosphorylation N/A PhosphoSite
CDK5 HTT 22135298 phosphorylation N/A PhosphoSite
CDK5 NR3C1 22135298 phosphorylation N/A PhosphoSite
CDK5 PIK3C3 22135298 phosphorylation N/A PhosphoSite
CDK5 BACE1 22135298 phosphorylation N/A PhosphoSite
CDK5 EPRS1 22135298 phosphorylation N/A PhosphoSite
CDK5 AMPH 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK5 CDK5R1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK5 CCDC88A 22135298 phosphorylation N/A PhosphoSite
CDK5 DRD2 22135298 phosphorylation N/A PhosphoSite
CDK5 LMTK2 22135298 phosphorylation N/A PhosphoSite
CDK5 XDH 22135298 phosphorylation N/A PhosphoSite
CDK5 FOXO1 22135298 phosphorylation N/A PhosphoSite
CDK5 PPP1CA 22135298 phosphorylation N/A PhosphoSite
CDK5 STMN3 22135298 phosphorylation N/A PhosphoSite
CDK5 PMAIP1 22135298 phosphorylation N/A PhosphoSite
CDK5 DBN1 22135298 phosphorylation N/A PhosphoSite
CDK5 FZR1 22135298 phosphorylation N/A PhosphoSite
CDK5 SRC 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK5 RPA2 22135298 phosphorylation N/A PhosphoSite
CDK5 PLD2 22135298 phosphorylation N/A PhosphoSite
CDK5 PTK2 22135298 phosphorylation N/A PhosphoSite
CDK5 AR 22135298 phosphorylation N/A PhosphoSite
CDK5 TPPP 22135298 phosphorylation N/A PhosphoSite
CDK5 PPARG 22135298 phosphorylation N/A PhosphoSite
CDK5 NDE1 22135298 phosphorylation N/A PhosphoSite
CDK5 TP53 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK5 CLOCK 22135298 phosphorylation N/A PhosphoSite
CDK5 CRMP1 22135298 phosphorylation N/A PhosphoSite
CDK5 ADD2 22135298 phosphorylation N/A PhosphoSite
CDK5 DNM1L 22135298 phosphorylation N/A PhosphoSite
CDK5 HIF1A 22135298 phosphorylation N/A PhosphoSite
CDK5 NEFL 22135298 phosphorylation N/A PhosphoSite
CDK5 ELAVL1 22135298 phosphorylation N/A PhosphoSite
CDK5 MAP2K1 22135298 phosphorylation N/A PhosphoSite
CDK5 MEF2D 22135298 phosphorylation N/A PhosphoSite
CDK5 PHACTR3 22135298 phosphorylation N/A PhosphoSite
CDK5 MYC 22135298 phosphorylation N/A PhosphoSite
CDK5 DPYSL3 22135298 phosphorylation N/A PhosphoSite
CDK5 PRKN 22135298 phosphorylation N/A PhosphoSite
CDK5 DPYSL2 22135298 phosphorylation N/A PhosphoSite
CDK5 RB1 22135298 phosphorylation N/A PhosphoSite
CDK5 NFE2L2 22135298 phosphorylation N/A PhosphoSite
CDK5 KDR 22135298 phosphorylation N/A PhosphoSite
CDK5 CTNNB1 22135298 phosphorylation N/A PhosphoSite
CDK5 STAT3 22135298 phosphorylation N/A PhosphoSite
CDK5 DNM1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK5 PIP5K1C 22135298 phosphorylation N/A PhosphoSite
CDK5 MEF2A 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CDK5 PPP1R2 22135298 phosphorylation N/A PhosphoSite
CDK5 PRNP 22135298 phosphorylation N/A PhosphoSite
CDK5 HTRA2 22135298 phosphorylation N/A PhosphoSite
CDK5 NOS3 22135298 phosphorylation N/A PhosphoSite
CDK5 DNMT1 22135298 phosphorylation N/A PhosphoSite
CDK5 ATM 22135298 phosphorylation N/A PhosphoSite
CDK5 HDAC5 22135298 phosphorylation N/A PhosphoSite
CDK5 LRRK2 22135298 phosphorylation N/A PhosphoSite
CDK5 AXIN1 22135298 phosphorylation N/A PhosphoSite
CDK5 PSEN1 22135298 phosphorylation N/A PhosphoSite
CDK5 TLN1 22135298 phosphorylation N/A PhosphoSite
CDK5 NFAT5 22135298 phosphorylation N/A PhosphoSite
CDK5 VIM 22135298 phosphorylation N/A PhosphoSite
CSNK1A1 CDK5 22135298 phosphorylation N/A PhosphoSite
CDK5RAP1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 CDK5RAP1 25361965 interaction type N/A PTMCode2
STX1A CDK5 25361965 interaction type N/A PTMCode2
CDK5 STX1A 25361965 interaction type N/A PTMCode2
CABLES2 CDK5 25361965 interaction type N/A PTMCode2
CDK5 CABLES2 25361965 interaction type N/A PTMCode2
CCNH CDK5 25361965 interaction type N/A PTMCode2
CDK5 CCNH 25361965 interaction type N/A PTMCode2
CDKN1A CDK5 25361965 interaction type N/A PTMCode2
CDK5 CDKN1A 25361965 interaction type N/A PTMCode2
CCND2 CDK5 25361965 interaction type N/A PTMCode2
CDK5 CCND2 25361965 interaction type N/A PTMCode2
TP53 CDK5 25361965 interaction type N/A PTMCode2
SYN1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 SYN1 25361965 interaction type N/A PTMCode2
APP CDK5 25361965 interaction type N/A PTMCode2
CDK5 APP 25361965 interaction type N/A PTMCode2
PPP1R1B CDK5 25361965 interaction type N/A PTMCode2
CDK5 PPP1R1B 25361965 interaction type N/A PTMCode2
CDK5 CDK5R2 25361965 interaction type N/A PTMCode2
CDK5R2 CDK5 25361965 interaction type N/A PTMCode2
CDK5R1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 AATK 25361965 interaction type N/A PTMCode2
AATK CDK5 25361965 interaction type N/A PTMCode2
CDK5 CSNK1D 25361965 interaction type N/A PTMCode2
CSNK1D CDK5 25361965 interaction type N/A PTMCode2
CDK5 PURA 25361965 interaction type N/A PTMCode2
PURA CDK5 25361965 interaction type N/A PTMCode2
CDK5 NDEL1 25361965 interaction type N/A PTMCode2
NDEL1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 DCX 25361965 interaction type N/A PTMCode2
DCX CDK5 25361965 interaction type N/A PTMCode2
CDK5 MAPT 25361965 interaction type N/A PTMCode2
MAPT CDK5 25361965 interaction type N/A PTMCode2
CDK5 CDK5RAP2 25361965 interaction type N/A PTMCode2
CDK5RAP2 CDK5 25361965 interaction type N/A PTMCode2
CDK5 CCNG1 25361965 interaction type N/A PTMCode2
CCNG1 CDK5 25361965 interaction type N/A PTMCode2
MEF2A CDK5 25361965 interaction type N/A PTMCode2
AMPH CDK5 25361965 interaction type N/A PTMCode2
SRC CDK5 25361965 interaction type N/A PTMCode2
CDK5 WASF1 25361965 interaction type N/A PTMCode2
WASF1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 NES 25361965 interaction type N/A PTMCode2
NES CDK5 25361965 interaction type N/A PTMCode2
CDK5 FYN 25361965 interaction type N/A PTMCode2
FYN CDK5 25361965 interaction type N/A PTMCode2
CDK5 DAB1 25361965 interaction type N/A PTMCode2
DAB1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 ABL1 25361965 interaction type N/A PTMCode2
ABL1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 SET 25361965 interaction type N/A PTMCode2
SET CDK5 25361965 interaction type N/A PTMCode2
DNM1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 STXBP1 25361965 interaction type N/A PTMCode2
STXBP1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 PCNA 25361965 interaction type N/A PTMCode2
PCNA CDK5 25361965 interaction type N/A PTMCode2
CDK5 CHN1 25361965 interaction type N/A PTMCode2
CHN1 CDK5 25361965 interaction type N/A PTMCode2
FCN2 CDK5 25361965 interaction type N/A PTMCode2
CDK5 FCN2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SH3GLB1 CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PCNA CDK5 14525934 25348397 7949095 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CDKN1A CDK5 15890360 23455922 23602568 24234451 25348397 association,physical association surface plasmon resonance,physical interaction,tandem affinity purification,surface plasmon resonance array ComPPI,IntAct
CCND1 CDK5 25348397 N/A physical interaction ComPPI
CDKN1B CDK5 14525934 15890360 23455922 23602568 24234451 25348397 25852190 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,surface plasmon resonance,physical interaction,footprinting,in vitro,tandem affinity purification,surface plasmon resonance array ComPPI,HPRD,IntAct
SET CDK5 11741927 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ODF1 CDK5 25348397 N/A physical interaction ComPPI
NUBP2 CDK5 25348397 N/A physical interaction ComPPI
KEAP1 CDK5 25348397 N/A physical interaction ComPPI
CDK5R1 CDK5 11583627 12223541 14521924 14525934 15689152 20133653 21220307 23602568 24234451 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,x-ray crystallography,physical interaction,ion exchange chromatography,protein kinase assay,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
HSP90AB1 CDK5 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CSNK1D CDK5 10500146 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK1 CDK5 25348397 N/A physical interaction,in vitro,in vivo ComPPI
NF2 CDK5 25348397 N/A physical interaction ComPPI
SRC CDK5 10544291 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RB1 CDK5 25348397 N/A physical interaction ComPPI
HDAC4 CDK5 25348397 N/A physical interaction ComPPI
FZR1 CDK5 25348397 N/A physical interaction ComPPI
GSK3B CDK5 14525934 15652488 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SCYL2 CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SYN1 CDK5 14525934 25348397 8702879 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HSP90AA1 CDK5 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ACTN1 CDK5 12223541 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NTRK1 CDK5 25348397 N/A physical interaction ComPPI
DAB1 CDK5 12077184 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN2 CDK5 25348397 N/A in vitro,in vivo ComPPI
BAG6 CDK5 25348397 N/A physical interaction ComPPI
TLN1 CDK5 25348397 N/A physical interaction ComPPI
DNM1 CDK5 12855954 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
WASF1 CDK5 14525934 16862120 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
STIP1 CDK5 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SUB1 CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PPP1CA CDK5 11320080 24234451 25348397 N/A pull down ComPPI,IntAct
MAP2K1 CDK5 11684694 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPT CDK5 17078951 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay,in vitro ComPPI,IntAct
PPARG CDK5 25348397 N/A two hybrid,physical interaction ComPPI
GORASP2 CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
STXBP1 CDK5 12963086 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ECT2 CDK5 25348397 N/A physical interaction ComPPI
EPRS1 CDK5 21220307 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAP1 CDK5 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RPE CDK5 25348397 N/A physical interaction ComPPI
NEDD4L CDK5 25348397 N/A physical interaction ComPPI
STX1A CDK5 14525934 25348397 9478941 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAPK10 CDK5 11823425 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EGFR CDK5 25348397 N/A physical interaction ComPPI
MBP CDK5 25348397 N/A physical interaction ComPPI
H1-5 CDK5 25348397 N/A physical interaction ComPPI
TCP1 CDK5 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CCT5 CDK5 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CCT7 CDK5 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
YBX3 CDK5 25348397 N/A physical interaction ComPPI
PURA CDK5 12972605 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MEF2A CDK5 12691662 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CABLES2 CDK5 11955625 14525934 23455922 23602568 24234451 25348397 25852190 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CABLES1 CDK5 10896159 11733001 11955625 14525934 20559324 23455922 23602568 24234451 25348397 25852190 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
CCNB1 CDK5 23455922 23602568 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
UBE2A CDK5 25348397 N/A physical interaction ComPPI
CCNG1 CDK5 14525934 25348397 9013862 N/A experimental interaction detection,in vivo ComPPI,HPRD
SYNJ1 CDK5 14525934 14704270 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
UCHL1 CDK5 25348397 N/A physical interaction ComPPI
AMPH CDK5 11113134 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CDK5 PPP1R2 11320080 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CDK5 CCND2 14525934 23455922 23602568 24234451 25348397 25416956 26871637 27107012 9422379 association,physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid,two hybrid ComPPI,HPRD,IntAct
CDK5 EZR 12769842 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CDK5 FYN 12372285 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CDK5 GRIN2A 11675505 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CDK5 DCX 14525934 14741103 15345747 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CDK5 CDK16 12084709 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CDK5 GAK 14525934 25348397 9013862 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CDK5 CDK5R2 10683146 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CDK5 PPP1R1B 10604473 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CDK5 CDC37 14525934 21163940 24234451 25348397 9150368 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro ComPPI,HPRD,IntAct
CDK5 NDEL1 12796778 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CDK5 NES 11278541 12832492 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CDK5 CDK5RAP1 11882646 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CDK5 FSD1 12154070 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CDK5 MIR9-1HG 10995546 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CDK5 CHN1 14525934 15013773 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
CDK5 PIP5K1C 14525934 17290217 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CDK5 PSEN1 12056836 14525934 21163940 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
CDK5 LMTK2 25348397 N/A physical interaction ComPPI
CDK5 CDK5RAP2 25348397 N/A physical interaction ComPPI
CDK5 TP53 10884347 11483158 12064478 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CDK5 PRKN 25348397 N/A physical interaction ComPPI
CDK5 NEDD4 25348397 N/A physical interaction ComPPI
CDK5 ALAS1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK5 H1-0 25348397 N/A physical interaction ComPPI
CDK5 RPL34 25348397 N/A physical interaction ComPPI
CDK5 KIF26B 25348397 N/A physical interaction ComPPI
CDK5 HTRA2 25348397 N/A physical interaction ComPPI
CDK5 APP 10936190 14525934 15178331 25348397 8764598 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CDK5 MAST1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CDK5 RNF32 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CDK5 GBP1 25348397 N/A physical interaction ComPPI
CDK5 CDC25B 25348397 N/A physical interaction ComPPI
CDK5 C2CD5 23455922 23602568 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 FIBP 23455922 23602568 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 TMEM94 23455922 23602568 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 DCLK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CCND3 23455922 23602568 24234451 25348397 association,physical association physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach ComPPI,IntAct
CDK5 CCNE1 25348397 N/A physical interaction ComPPI
CDK5 GLUD1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 HSP90AA2P 25348397 N/A physical interaction ComPPI
CDK5 CCNA2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CCT6A 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CCT3 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CCT8 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CCT4 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CCT2 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CDK3 23455922 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CDK18 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK5 CHFR 25348397 N/A physical interaction ComPPI
CDK5 CCNI 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK5 CCNI2 25348397 N/A physical interaction ComPPI
CDK5 CDK20 25348397 N/A physical interaction ComPPI
CDK5 CDK14 25348397 N/A physical interaction ComPPI
CDK5 HTR6 25348397 N/A physical interaction ComPPI
CDK5 FBXW11 25348397 N/A physical interaction ComPPI
CDK5 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CDK5 STUB1 25348397 26206088 27898060 N/A physical interaction ComPPI,OmniPath
CDK5 CDC25A 25348397 N/A physical interaction ComPPI
CDK5 CDC25C 25348397 N/A physical interaction ComPPI
CDK5 CNPPD1 25348397 N/A physical interaction ComPPI
CDK5 AURKC 25348397 N/A physical interaction ComPPI
CDK5 PRCC 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK5 SEPTIN7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK5 DIS3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK5 CHORDC1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK5 COPZ1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK5 SEPTIN11 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK5 PIKFYVE 25348397 N/A physical interaction ComPPI
CDK5 AATK 25348397 N/A anti bait coimmunoprecipitation ComPPI
CDK5 CRELD2 21900206 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK5 DBN1 23979715 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
CDK5 CCNC 24234451 25348397 25852190 physical association anti tag coimmunoprecipitation ComPPI,IntAct
CDK5 SPDYE4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDK5 SPDYA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SARNP CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HSCB CDK5 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
PAN CDK5 15575970 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FZ3 CDK5 25348397 N/A anti tag coimmunoprecipitation ComPPI
CDK5 CDK5 11583627 14525934 N/A experimental interaction detection HPRD
ABL1 CDK5 10896159 14525934 N/A experimental interaction detection HPRD
CDK5 ERBB3 12824184 14525934 N/A experimental interaction detection HPRD
GAPDH CDK5 24234451 30021884 physical association cross-linking study IntAct
CDK5 DNM1 12855954 18088087 19651622 27898060 stimulant N/A OmniPath
CDK5 STMN3 22577147 24589734 27898060 N/A N/A OmniPath
CDK5 SRC 10544291 17192257 18691976 19369195 19415658 21442427 27898060 7488156 stimulant N/A OmniPath
CDK5 CTNNB1 17009320 27898060 N/A N/A OmniPath
CDK5 SYN1 10880969 27898060 8702879 stimulant N/A OmniPath
CDK5 DBN1 24637538 27898060 N/A N/A OmniPath
CDK5 STMN1 20630875 27898060 inhibition N/A OmniPath
FYN CDK5 12372285 14757045 16497976 18691976 19413330 19901323 20068231 27898060 stimulant N/A OmniPath
CSNK1A1 CDK5 10500146 27898060 N/A N/A OmniPath
CDK5 NOS3 16270749 19962452 20213743 27898060 inhibition N/A OmniPath
CDK5 TRPV1 17194758 22451679 23077056 27898060 stimulant N/A OmniPath
CDK5 NDEL1 11163260 12796778 18669648 19413330 20068231 27898060 stimulant N/A OmniPath
CDK5 MAPK10 11823425 27898060 inhibition,stimulant N/A OmniPath
CDK5 DNMT1 21565170 27898060 stimulant N/A OmniPath
CDK5 PPP1R1B 10604473 27898060 stimulant N/A OmniPath
CDK5 PRNP 24360565 25572400 27898060 N/A N/A OmniPath
CDK5 PTPN2 15030318 18669648 18767875 19413330 19651622 20068231 27898060 N/A N/A OmniPath
CDK5 TTK 18680479 27898060 N/A N/A OmniPath
CDK5 RB1 15741232 27898060 inhibition N/A OmniPath
CDK5 CRMP1 16611631 18003833 27898060 stimulant N/A OmniPath
CDK5 MAP2K1 11684694 18691976 27898060 inhibition N/A OmniPath
CDK5 APP 10936190 11877420 15178331 27898060 8131745 8764598 stimulant N/A OmniPath
CDK5 HTT 15911879 17611284 18691976 19413330 24505464 25799558 27898060 stimulant N/A OmniPath
CDK5 FZR1 18818692 22654103 23589330 26083744 27898060 N/A N/A OmniPath
CDK5 ATM 19151707 23365634 27898060 stimulant N/A OmniPath
CDK5 SH3GLB1 21499257 27898060 N/A N/A OmniPath
CDK5 NFAT5 21209322 27898060 stimulant N/A OmniPath
CDK5 PTK2 11160818 12941275 17096371 20519501 21876001 25525271 27898060 stimulant N/A OmniPath
CDK5 TP53 10570149 10884347 11483158 11554766 11740489 11780126 12064478 12093737 12907596 14749479 15526030 15657359 15701641 15706352 15866171 16377624 16601678 16738336 16793543 17108107 17210684 17287340 17349958 17349959 17567906 17591690 17967874 18160537 19413330 19465479 19664995 19828042 19857493 19965871 20018442 20171273 20514025 20811699 21057547 21317932 22525275 22878263 23149944 24196445 24379358 25778922 25944899 26236013 27898060 9372954 stimulant N/A OmniPath
ABL1 CDK5 10500146 10896159 11113134 12372285 14757045 16497976 18083107 18691976 19369195 19413330 19534553 19690332 19901323 20068231 20841568 27898060 stimulant N/A OmniPath
CDK5 PXN 18042622 27898060 N/A N/A OmniPath
CDK5 EZR 12769842 27898060 stimulant N/A OmniPath
CDK5 PMAIP1 21145489 25829494 26411306 27898060 inhibition N/A OmniPath
CDK5 CLOCK 24235147 27898060 stimulant N/A OmniPath
CDK5 CAMKK2 22778263 27898060 inhibition N/A OmniPath
CDK5 RPA2 19671522 21664290 26237679 27898060 N/A N/A OmniPath
CDK5 MEF2A 12586839 12691662 16371476 16484498 27898060 inhibition,stimulant N/A OmniPath
CDK5 AR 11396978 17043241 17325038 17698582 21799006 22014572 24441043 25691442 25851605 25982277 27898060 stimulant N/A OmniPath
CDK5 NFE2L2 25909891 27898060 N/A N/A OmniPath
CDK5 PIK3C3 20513426 27898060 inhibition N/A OmniPath
CDK5 PPP1CA 11320080 12202491 17202132 27898060 inhibition N/A OmniPath
CDK5 PAK1 11604394 12176334 19413330 19664994 19664995 20058876 27898060 inhibition N/A OmniPath
CDK5 VIM 16565220 16964243 17081983 17287340 17924679 18669648 18691976 19007248 19369195 19413330 19690332 21465480 27898060 N/A N/A OmniPath
CDK5 PPARG 21892191 22078880 22584573 27898060 N/A N/A OmniPath
CDK5 PRKCI 15314172 27898060 N/A N/A OmniPath
CDK5 PSEN1 12056836 21163940 27898060 stimulant N/A OmniPath
CDK5 SEPTIN5 17224448 27898060 N/A N/A OmniPath
CDK5 BACE1 26317805 27898060 N/A N/A OmniPath
CDK5 MAPT 10620503 11104762 11181841 1181841 12226093 12387894 12414518 12435421 12484777 12614922 12765608 12801934 1330687 15136685 15312816 15664690 15973541 15994305 16568235 16877359 17008320 17078951 17270732 17287340 17314187 17761554 18510355 19413330 19415658 19527721 19562805 19651622 20068231 20639351 21215781 24113872 24116116 27898060 7566346 7592534 8282104 8858002 9199504 9353289 9546672 9565682 9735171 9771888 9832145 inhibition,stimulant N/A OmniPath
CDK5 TLN1 19363486 24793790 26091349 27898060 stimulant N/A OmniPath
MAP2K7 CDK5 27898060 9038181 N/A N/A OmniPath
CDK5 STAT3 15096606 27898060 stimulant N/A OmniPath
CDK5 BUB1B 17785528 19015317 27898060 N/A N/A OmniPath
CDK5 PRKN 17327227 19050041 27898060 inhibition,stimulant N/A OmniPath
CDK5 HTRA2 21701498 27898060 stimulant N/A OmniPath
CDK5 NR3C1 12351702 16125839 17185395 17440046 19812390 19841061 20047289 20156337 22401993 22911818 24024586 27898060 inhibition,stimulant N/A OmniPath
CDK5 CDK5R1 11389014 11583627 12223541 15013773 15689152 17036052 17121855 17591690 17762160 18326489 20097924 20133653 21220307 22654103 23602568 26186194 27898060 inhibition N/A OmniPath
CDK5R1 CDK5 10903889 11389014 11583627 12223541 15013773 15689152 17036052 17591690 17762160 18326489 20133653 21220307 22654103 23602568 26186194 27898060 stimulant N/A OmniPath
CDK5 NEFL 16452125 27898060 N/A N/A OmniPath
CDK5 PLD2 18625302 27898060 N/A N/A OmniPath
CDK5 MEF2D 16356933 27898060 N/A N/A OmniPath
CDK5 CCDC88A 26286990 27898060 N/A N/A OmniPath
CDK5 CORO1A 26823173 27898060 stimulant N/A OmniPath
CDK5 AMPH 11113134 17419807 27898060 stimulant N/A OmniPath
CDK5 NEFH 27898060 7760048 stimulant N/A OmniPath
CDK5 MYBPC3 17560599 18802026 20151718 27898060 N/A N/A OmniPath
CDK5 EPRS1 17287340 17924679 18220336 18669648 18691976 19369195 19413330 19647514 19690332 21220307 27898060 inhibition N/A OmniPath
CDK5 DNM1L 17553808 27898060 N/A N/A OmniPath
CDK5 PPP1R2 11320080 27898060 8288648 N/A N/A OmniPath
CDK5 DAB1 12077184 27898060 stimulant N/A OmniPath
CDK5 CSN1S1 17646876 27898060 N/A N/A OmniPath
CDK5 NDE1 16682949 26206584 27898060 N/A N/A OmniPath
CDK5 AGAP2 18487454 27898060 stimulant N/A OmniPath
CDK5 LMTK2 12832520 22220831 27898060 inhibition,stimulant N/A OmniPath
CDK5 CDK16 12084709 18691976 27898060 N/A N/A OmniPath
CDK5 DPYSL3 16611631 27898060 stimulant N/A OmniPath
CDK5 STXBP2 17716669 27898060 inhibition N/A OmniPath
CDK5 MEF2C 15340086 27898060 N/A N/A OmniPath
CDK5 PIP5K1C 15738269 17290217 27898060 inhibition N/A OmniPath
CDK5 XDH 25831123 27898060 N/A N/A OmniPath
CDK5 TPPP 15822905 17693641 18669648 19413330 27898060 N/A N/A OmniPath
CDK5 PHACTR3 21487013 27898060 N/A N/A OmniPath
CDK5 IGFBP5 17496250 27898060 N/A N/A OmniPath
CDK5 NES 11278541 12832492 17036052 18669648 20068231 27898060 N/A N/A OmniPath
CDK5 POLR2F 11486042 27898060 N/A N/A OmniPath
CDK5 RASGRF2 15128856 27898060 stimulant N/A OmniPath

Visualization










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