Gene Information gene info

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GENE：USP10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP10
FullNmae ubiquitin specific peptidase 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12608
EnsembleID ENSG00000103194
Uniprot Q14694

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP10 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP10 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP10 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
USP10 GO:0002039,GO:0003723,GO:0004197,GO:0004843,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005769,GO:0005769,GO:0005829,GO:0005829,GO:0005829,GO:0006914,GO:0006974,GO:0010506,GO:0010506,GO:0016579,GO:0016579,GO:0016579,GO:0019985,GO:0022626,GO:0030330,GO:0030330,GO:0032991,GO:0043124,GO:0044325,GO:0045111,GO:0062030,GO:0071347,GO:0072344,GO:0140678

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
USP10 TBX21 23180781 24845384 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR USP10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 USP10 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 USP10 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 USP10 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 USP10 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00003380CC USP10 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 USP10 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 USP10 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AD002 USP10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 USP10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F USP10 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 USP10 22135298 phosphorylation N/A PhosphoSite
ATM USP10 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CDC5L USP10 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAA2 USP10 25348397 N/A physical interaction ComPPI
NPM1 USP10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCNA USP10 25348397 N/A physical interaction ComPPI
TRAF6 USP10 25348397 N/A physical interaction ComPPI
VCP USP10 25348397 N/A physical interaction ComPPI
SNAI1 USP10 25348397 N/A physical interaction ComPPI
ZC3H12A USP10 24234451 24270572 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RACK1 USP10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPL10 USP10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TBP USP10 25348397 N/A physical interaction ComPPI
JUN USP10 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
AR USP10 16368182 25348397 27898060 N/A physical interaction ComPPI,OmniPath
EIF4G1 USP10 25348397 N/A physical interaction ComPPI
PRKAA1 USP10 25348397 N/A physical interaction ComPPI
UBC USP10 25348397 N/A physical interaction ComPPI
NTRK1 USP10 25348397 N/A physical interaction ComPPI
YBX1 USP10 23986595 24234451 25348397 25497084 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC USP10 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
HNRNPL USP10 25348397 N/A physical interaction ComPPI
SCNN1G USP10 14525934 18632802 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CFTR USP10 19398555 20215869 21455491 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
PABPC1 USP10 25348397 N/A physical interaction ComPPI
RAD51 USP10 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPS6 USP10 25348397 N/A physical interaction ComPPI
RNF168 USP10 25348397 N/A physical interaction ComPPI
MDM2 USP10 25348397 N/A physical interaction ComPPI
SCNN1A USP10 14525934 18632802 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ZEB1 USP10 25348397 N/A physical interaction ComPPI
PTEN USP10 25348397 N/A physical interaction ComPPI
IBTK USP10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 USP10 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GAR1 USP10 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NOP56 USP10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TANK USP10 25348397 N/A physical interaction ComPPI
HECW2 USP10 25348397 N/A physical interaction ComPPI
PPP4R2 USP10 25348397 N/A physical interaction ComPPI
ULK1 USP10 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF4G3 USP10 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TARDBP USP10 25348397 N/A physical interaction ComPPI
SF3B3 USP10 25348397 N/A physical interaction ComPPI
USP10 SNX3 14525934 18632802 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
USP10 G3BP1 11439350 14525934 19615732 21455491 23230274 24234451 24998844 25348397 26344197 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,bimolecular fluorescence complementation,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
USP10 G3BP2 19615732 24234451 25348397 25416956 physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
USP10 CELF1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP10 TP53 25348397 N/A physical interaction ComPPI
USP10 WAPL 25348397 N/A physical interaction ComPPI
USP10 ZC3H18 25348397 N/A physical interaction ComPPI
USP10 USP15 25348397 N/A physical interaction ComPPI
USP10 UBE2S 25348397 N/A physical interaction ComPPI
USP10 TSKS 25348397 N/A physical interaction ComPPI
USP10 TRPM8 25348397 N/A physical interaction ComPPI
USP10 ZNF281 25348397 N/A physical interaction ComPPI
USP10 ANKRD28 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
USP10 PPP6R1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
USP10 PPP6R3 25348397 N/A physical interaction ComPPI
USP10 IKBKG 24234451 24270572 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USP10 TBX21 25348397 N/A physical interaction ComPPI
USP10 SIRT6 25348397 N/A physical interaction ComPPI
USP10 KLHDC3 25348397 N/A physical interaction ComPPI
USP10 KMT2E 25348397 N/A physical interaction ComPPI
USP10 H2AC20 25348397 N/A physical interaction ComPPI
USP10 MSH2 25348397 N/A physical interaction ComPPI
USP10 ANKRD44 25348397 N/A physical interaction ComPPI
USP10 ANKRD52 25348397 N/A physical interaction ComPPI
USP10 AARSD1 25348397 N/A physical interaction ComPPI
USP10 PPP4R3A 25348397 N/A physical interaction ComPPI
USP10 GFAP 25348397 N/A physical interaction ComPPI
USP10 PPP6R2 25348397 N/A physical interaction ComPPI
USP10 CYLD 25348397 N/A physical interaction ComPPI
USP10 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
ATM USP10 20096447 27898060 N/A N/A OmniPath

Visualization










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