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GENE：ATP6V1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6V1A
FullNmae ATPase H+ transporting V1 subunit A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:851
EnsembleID ENSG00000114573
Uniprot P38606

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6V1A autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V1A autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP6V1A GO:0000139,GO:0000221,GO:0005515,GO:0005524,GO:0005654,GO:0005765,GO:0005765,GO:0005765,GO:0005829,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005902,GO:0006879,GO:0007035,GO:0007042,GO:0007042,GO:0010008,GO:0015986,GO:0016020,GO:0016241,GO:0016324,GO:0016469,GO:0016887,GO:0030141,GO:0030665,GO:0033176,GO:0036295,GO:0043231,GO:0046933,GO:0046961,GO:0048388,GO:0051452,GO:0061795,GO:0070062,GO:0097401,GO:0098850,GO:1902495,GO:1902600,GO:1902600,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6V1A hsa:523 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa04966 Collecting duct acid secretion - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6V1A hsa:523 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ATP6V1A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ATP6V1A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ATP6V1A 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATP6V1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP6V1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP6V1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ATP6V1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 ATP6V1A 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000CF1D2 ATP6V1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000017DBB8 ATP6V1A 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E ATP6V1A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F ATP6V1A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 ATP6V1A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C ATP6V1A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA ATP6V1A 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP6V1G1 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PKP4 ATP6V1A 25348397 N/A anti bait coimmunoprecipitation ComPPI
TFRC ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPN1 ATP6V1A 25348397 N/A physical interaction ComPPI
FTH1 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDKN1A ATP6V1A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TK1 ATP6V1A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
XIAP ATP6V1A 25348397 N/A physical interaction ComPPI
SMN1 ATP6V1A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TUFM ATP6V1A 11741979 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PDCD10 ATP6V1A 25348397 N/A physical interaction ComPPI
RRAS ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CD9 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
JUN ATP6V1A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SERPINA3 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
VAPA ATP6V1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL3 ATP6V1A 25348397 N/A physical interaction ComPPI
PDIA3 ATP6V1A 25348397 N/A physical interaction ComPPI
CTSD ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NTRK1 ATP6V1A 25348397 N/A physical interaction ComPPI
HNRNPL ATP6V1A 25348397 N/A physical interaction ComPPI
VCL ATP6V1A 25348397 N/A physical interaction ComPPI
PDLIM7 ATP6V1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC1 ATP6V1A 25348397 N/A physical interaction ComPPI
S100A11 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RAB1A ATP6V1A 25348397 N/A physical interaction ComPPI
EIF3F ATP6V1A 25348397 N/A physical interaction ComPPI
RAB2A ATP6V1A 25348397 N/A physical interaction ComPPI
RALB ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6AP2 ATP6V1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA2 ATP6V1A 25348397 N/A physical interaction ComPPI
RBBP4 ATP6V1A 25348397 N/A physical interaction ComPPI
ABCE1 ATP6V1A 25348397 N/A physical interaction ComPPI
VDAC2 ATP6V1A 25348397 N/A physical interaction ComPPI
ATP1A1 ATP6V1A 25348397 N/A physical interaction ComPPI
VAMP8 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
VAMP7 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
STX8 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SCARB2 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
BANF1 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NCSTN ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CSE1L ATP6V1A 25348397 N/A physical interaction ComPPI
PRDX6 ATP6V1A 25348397 N/A physical interaction ComPPI
RAB9A ATP6V1A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CUL7 ATP6V1A 25348397 N/A physical interaction ComPPI
ELAVL1 ATP6V1A 25348397 N/A physical interaction ComPPI
DNAJC5 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CAPN1 ATP6V1A 25348397 N/A physical interaction ComPPI
SOD1 ATP6V1A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TGOLN2 ATP6V1A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ATP6V1A ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP6V1A ATP5F1A 25348397 N/A physical interaction ComPPI
ATP6V1A ATP5F1C 25348397 N/A physical interaction ComPPI
ATP6V1A TXNL1 25348397 N/A physical interaction ComPPI
ATP6V1A RMDN3 25348397 N/A physical interaction ComPPI
ATP6V1A ZNF706 25348397 N/A physical interaction ComPPI
ATP6V1A UBXN1 25348397 N/A physical interaction ComPPI
ATP6V1A PRDX2 25348397 N/A physical interaction ComPPI
ATP6V1A EIF4A1 25348397 N/A physical interaction ComPPI
ATP6V1A MARCKSL1 25348397 N/A physical interaction ComPPI
ATP6V1A UBR1 25348397 N/A physical interaction ComPPI
ATP6V1A USP5 25348397 N/A physical interaction ComPPI
ATP6V1A TXNDC5 25348397 N/A physical interaction ComPPI
ATP6V1A UBE2S 25348397 N/A physical interaction ComPPI
ATP6V1A TIPRL 25348397 N/A physical interaction ComPPI
ATP6V1A FBXO6 25348397 N/A physical interaction ComPPI
ATP6V1A HSPD1 25348397 N/A physical interaction ComPPI
ATP6V1A MTAP 25348397 N/A physical interaction ComPPI
ATP6V1A MTPN 25348397 N/A physical interaction ComPPI
ATP6V1A ACADM 25348397 N/A physical interaction ComPPI
ATP6V1A ATP1A3 25348397 N/A physical interaction ComPPI
ATP6V1A VDAC3 25348397 N/A physical interaction ComPPI
ATP6V1A DDOST 25348397 N/A physical interaction ComPPI
ATP6V1A EEF1E1 25348397 N/A physical interaction ComPPI
ATP6V1A MCMBP 25348397 N/A physical interaction ComPPI
ATP6V1A SHMT2 25348397 N/A physical interaction ComPPI
ATP6V1A DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6V1A RAB5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6V1A GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6V1A HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A A2M 17174955 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
ATP6V1A MYOF 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A RAB35 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A CHMP2B 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A CHMP5 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A CD63 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A TMOD3 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A TACSTD2 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A VTI1B 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A GNB1 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A IST1 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A FLOT1 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A ATP6V0A1 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1A RRAGC 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP6V1A OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP6V1A PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
RAB22A ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4A3 ATP6V1A 25348397 N/A physical interaction ComPPI
COX4I1 ATP6V1A 25348397 N/A physical interaction ComPPI
AHCY ATP6V1A 25348397 N/A physical interaction ComPPI
ATP6V1B2 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct

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