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GENE：CISD2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CISD2
FullNmae CDGSH iron sulfur domain 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24212
EnsembleID ENSG00000145354
Uniprot Q8N5K1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CISD2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CISD2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CISD2 GO:0000422,GO:0003723,GO:0005515,GO:0005741,GO:0005741,GO:0005783,GO:0005789,GO:0010506,GO:0016020,GO:0032991,GO:0042803,GO:0046872,GO:0051537,GO:0051537,GO:0097038

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CISD2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A CISD2 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CISD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CISD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CISD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CISD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CISD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CISD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 CISD2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AD002 CISD2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC379 CISD2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000211070 CISD2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E CISD2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 CISD2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD CISD2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 CISD2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 CISD2 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000085F64 CISD2 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003380CC CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FAA8C CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001481F9 CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000221168 CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CC20C CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075BDAA CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EC1BE CISD2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LMNA CISD2 25348397 N/A physical interaction ComPPI
BCL2L2 CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NRG4 CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PNKP CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPP1 CISD2 25348397 N/A physical interaction ComPPI
PVR CISD2 25348397 N/A physical interaction ComPPI
IER3 CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VDAC1 CISD2 25348397 N/A physical interaction ComPPI
VDAC2 CISD2 25348397 N/A physical interaction ComPPI
EHHADH CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CHRND CISD2 25348397 N/A physical interaction ComPPI
ATXN3 CISD2 25348397 N/A physical interaction ComPPI
BCL2 CISD2 25348397 N/A physical interaction ComPPI
ELAVL1 CISD2 25348397 N/A physical interaction ComPPI
LTBR CISD2 25348397 N/A physical interaction ComPPI
IL17RB CISD2 25348397 N/A physical interaction ComPPI
BET1 CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAMP4 CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IKBKE CISD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GAST CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COX4I1 CISD2 25348397 N/A physical interaction ComPPI
VDAC3 CISD2 25348397 N/A physical interaction ComPPI
APOL2 CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KIR2DL3 CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GH1 CISD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IL1R2 CISD2 25348397 N/A physical interaction ComPPI
APP CISD2 25348397 N/A physical interaction ComPPI
NRG1 CISD2 25348397 N/A physical interaction ComPPI
COX6B1 CISD2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
HLA-C CISD2 25348397 N/A physical interaction ComPPI
TTPA CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDIPT CISD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CISD2 NDUFA4 25348397 N/A physical interaction ComPPI
CISD2 CLN6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CISD2 BCL2 20010695 27898060 stimulant N/A OmniPath

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