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GENE：FEZ1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FEZ1
FullNmae fasciculation and elongation protein zeta 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3659
EnsembleID ENSG00000149557
Uniprot Q99689

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FEZ1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEZ1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FEZ1 GO:0005080,GO:0005515,GO:0005737,GO:0005794,GO:0005813,GO:0005874,GO:0005886,GO:0007155,GO:0007399,GO:0007411,GO:0010976,GO:0021766,GO:0030010,GO:0030424,GO:0030425,GO:0030426,GO:0043015,GO:0043025,GO:0051654,GO:0061881,GO:0070584,GO:0071363,GO:1902902

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FEZ1 hsa:9638 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NEK1 FEZ1 14690447 23180781 physical association two hybrid,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 FEZ1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 FEZ1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 FEZ1 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FEZ1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FEZ1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FEZ1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FEZ1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FEZ1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
MARK1 FEZ1 22135298 phosphorylation N/A PhosphoSite
MARK2 FEZ1 22135298 phosphorylation N/A PhosphoSite
MARK3 FEZ1 22135298 phosphorylation N/A PhosphoSite
FEZ1 SAP30L 25361965 interaction type N/A PTMCode2
SAP30L FEZ1 25361965 interaction type N/A PTMCode2
FEZ1 DRAP1 25361965 interaction type N/A PTMCode2
DRAP1 FEZ1 25361965 interaction type N/A PTMCode2
FEZ1 NBR1 25361965 interaction type N/A PTMCode2
NBR1 FEZ1 25361965 interaction type N/A PTMCode2
FEZ1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ FEZ1 25361965 interaction type N/A PTMCode2
FEZ1 SMARCD1 25361965 interaction type N/A PTMCode2
SMARCD1 FEZ1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STAR FEZ1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NDUFB9 FEZ1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TTR FEZ1 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACTG1 FEZ1 25348397 N/A physical interaction ComPPI
TAF9 FEZ1 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
GEMIN7 FEZ1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LANCL2 FEZ1 25348397 N/A physical interaction ComPPI
SMARCD1 FEZ1 14525934 16484223 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
NBR1 FEZ1 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
CIB1 FEZ1 11856312 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
FEZ1 PRKCZ 14525934 25348397 9971736 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
FEZ1 BRD1 25348397 N/A two hybrid,physical interaction ComPPI
FEZ1 TLK2 25348397 N/A two hybrid,physical interaction ComPPI
FEZ1 WWC1 14525934 16484223 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FEZ1 CLASP2 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
FEZ1 RAI14 14525934 16484223 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FEZ1 TEDC2 14525934 16484223 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FEZ1 PDCD7 14525934 16169070 16484223 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 SMC3 14525934 16484223 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FEZ1 RAB3GAP2 14525934 16484223 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
FEZ1 TBC1D25 14525934 16484223 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FEZ1 SCOC 14525934 16484223 22354037 24234451 25348397 colocalization two hybrid,physical interaction,fluorescence microscopy,two hybrid ComPPI,HPRD,IntAct
FEZ1 IMMT 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FEZ1 BARD1 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FEZ1 NEK1 14525934 14690447 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
FEZ1 CEP126 15383276 24234451 25348397 physical association two hybrid,pull down ComPPI,IntAct
FEZ1 RIF1 14525934 15383276 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
FEZ1 TOMM20 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 TXNDC9 14525934 16169070 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 DRAP1 14525934 16484223 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FEZ1 FEZ2 14525934 16484223 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FEZ1 COL9A2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 PTH 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 GTF2F1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 PTPRS 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 P4HB 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 TAC3 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FEZ1 HTATSF1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 DNAAF5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 BORA 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FEZ1 PPP4R3B 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FEZ1 DIS3L2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 OLFML3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FEZ1 SAP30L 14525934 16484223 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FEZ1 HTT 14525934 15383276 17500595 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
FEZ1 PTN 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FEZ1 DISC1 12874605 14525934 25348397 27898060 N/A physical interaction,two hybrid ComPPI,HPRD,OmniPath
FEZ1 ZNF251 25348397 N/A physical interaction ComPPI
FEZ1 RAB3GAP1 25348397 N/A physical interaction ComPPI
FEZ1 MEST 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FEZ1 SERPINH1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FEZ1 C8ORF33 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FEZ1 HAP1 25348397 N/A physical interaction ComPPI
FEZ1 LRIF1 15383276 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FEZ1 UBE4B 25348397 N/A physical interaction ComPPI
FEZ1 AK6 25348397 N/A physical interaction ComPPI
FEZ1 ANK3 25348397 N/A physical interaction ComPPI
FEZ1 DGKD 25348397 N/A physical interaction ComPPI
FEZ1 ZYG11A 25348397 N/A physical interaction ComPPI
FEZ1 NELFA 25348397 N/A physical interaction ComPPI
FEZ1 TUBA3C 25348397 N/A physical interaction ComPPI
FEZ1 CEP192 25348397 N/A physical interaction ComPPI
FEZ1 KLHDC2 25348397 N/A physical interaction ComPPI
FEZ1 AURKA 25348397 N/A physical interaction ComPPI
FEZ1 MRS2 25348397 N/A physical interaction ComPPI
FEZ1 SELENON 25348397 N/A physical interaction ComPPI
FEZ1 IFT140 25348397 N/A physical interaction ComPPI
FEZ1 MED25 25348397 N/A physical interaction ComPPI
FEZ1 MYO5A 25348397 N/A physical interaction ComPPI
FEZ1 ASPM 25348397 N/A physical interaction ComPPI
FEZ1 ATP12A 25348397 N/A physical interaction ComPPI
FEZ1 CREB1 25348397 N/A physical interaction ComPPI
FEZ1 ZNF638 25348397 N/A physical interaction ComPPI
FEZ1 SPECC1L 25348397 N/A physical interaction ComPPI
FEZ1 SCCPDH 25348397 N/A physical interaction ComPPI
FEZ1 PLK1 25348397 N/A physical interaction ComPPI
FEZ1 CKAP4 25348397 N/A physical interaction ComPPI
FEZ1 MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
FEZ1 UVRAG 22354037 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
FEZ1 ULK1 22354037 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CSTF2 FEZ1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCL7 FEZ1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TAF1D FEZ1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAM16 FEZ1 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FEZ1 FEZ1 14525934 16484223 N/A experimental interaction detection,two hybrid HPRD
FEZ1 KHC 20547877 24234451 association cosedimentation in solution,pull down IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B222A FEZ1 27087310 direct interaction,inhibition N/A NPInter

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