GENE：GALNT2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GALNT2 |
| FullNmae | polypeptide N-acetylgalactosaminyltransferase 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4124 |
| EnsembleID | ENSG00000143641 |
| Uniprot | Q10471 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GALNT2 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| GALNT2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| GALNT2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| GALNT2 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GALNT2 | GO:0000139,GO:0000139,GO:0004653,GO:0004653,GO:0004653,GO:0005515,GO:0005576,GO:0005789,GO:0005794,GO:0005794,GO:0005795,GO:0006493,GO:0006493,GO:0016020,GO:0016266,GO:0016266,GO:0018242,GO:0018243,GO:0030145,GO:0030246,GO:0032580,GO:0048471,GO:0051604 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| GALNT2 | hsa:2590 | path:hsa00512 | Mucin type O-glycan biosynthesis - Homo sapiens (human) |
| GALNT2 | hsa:2590 | path:hsa00514 | Other types of O-glycan biosynthesis - Homo sapiens (human) |
| GALNT2 | hsa:2590 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | GALNT2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | GALNT2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | GALNT2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | GALNT2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | GALNT2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | GALNT2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | GALNT2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | GALNT2 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | GALNT2 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000324096 | GALNT2 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00002971AB | GALNT2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001C308D | GALNT2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000075BDA4 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004D84DB | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B538 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F14FE | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D4A78 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023F008 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000160683 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009A9A2 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000105D19 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001270D3 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001938D9 | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | GALNT2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMNA | GALNT2 | 25348397 | N/A | physical interaction | ComPPI |
| MRM3 | GALNT2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| KASH5 | GALNT2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| PEX19 | GALNT2 | 25348397 | N/A | physical interaction | ComPPI |
| PRPF40A | GALNT2 | 25348397 | N/A | physical interaction | ComPPI |
| PTPN1 | GALNT2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HNRNPL | GALNT2 | 25348397 | N/A | physical interaction | ComPPI |
| OCRL | GALNT2 | 24234451 25107275 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| TRIM25 | GALNT2 | 25348397 | N/A | physical interaction | ComPPI |
| TGOLN2 | GALNT2 | 24234451 25348397 29568061 | association | pull down,physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| NOD2 | GALNT2 | 21699783 24234451 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
| RPS15A | GALNT2 | 25348397 | N/A | physical interaction | ComPPI |
| SLC25A4 | GALNT2 | 25348397 | N/A | physical interaction | ComPPI |
| GALNT2 | ZMPSTE24 | 25348397 | N/A | physical interaction | ComPPI |
| GALNT2 | MUC1 | 12754287 12925576 14525934 27898060 9295285 9312074 | N/A | experimental interaction detection | HPRD,OmniPath |