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GENE：RAB3GAP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAB3GAP2
FullNmae RAB3 GTPase activating non-catalytic protein subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17168
EnsembleID ENSG00000118873
Uniprot Q9H2M9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAB3GAP2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAB3GAP2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RAB3GAP2 GO:0005085,GO:0005096,GO:0005515,GO:0005515,GO:0005789,GO:0005829,GO:0005829,GO:0005886,GO:0006886,GO:0008047,GO:0030234,GO:0031267,GO:0032991,GO:0043087,GO:0043087,GO:0097051,GO:1903061,GO:1903373,GO:2000786

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 RAB3GAP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RAB3GAP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RAB3GAP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RAB3GAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC RAB3GAP2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 RAB3GAP2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000324096 RAB3GAP2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000285DCB RAB3GAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000001C659 RAB3GAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E RAB3GAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000204177 RAB3GAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A RAB3GAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF RAB3GAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VCP RAB3GAP2 25348397 N/A physical interaction ComPPI
SHC1 RAB3GAP2 25348397 N/A physical interaction ComPPI
CPNE1 RAB3GAP2 25348397 N/A physical interaction ComPPI
FEZ1 RAB3GAP2 14525934 16484223 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
VAPA RAB3GAP2 25348397 N/A physical interaction ComPPI
PAXIP1 RAB3GAP2 25348397 N/A physical interaction ComPPI
NTRK1 RAB3GAP2 25348397 N/A physical interaction ComPPI
CANX RAB3GAP2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CFTR RAB3GAP2 25348397 N/A physical interaction ComPPI
ARF6 RAB3GAP2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VAPB RAB3GAP2 25348397 N/A physical interaction ComPPI
GABPA RAB3GAP2 25348397 N/A physical interaction ComPPI
GABARAP RAB3GAP2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB3GAP2 EXOSC6 14525934 15231747 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RAB3GAP2 PTP4A3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB3GAP2 MAP1LC3A 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB3GAP2 RBM26 25348397 N/A physical interaction ComPPI
RAB3GAP2 NUP43 25348397 N/A physical interaction ComPPI
RAB3GAP2 UTP20 25348397 N/A physical interaction ComPPI
RAB3GAP2 SIRT2 25348397 N/A physical interaction ComPPI
RAB3GAP2 TRIM25 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00008BE6B0 RAB3GAP2 27087310 direct interaction,inhibition N/A NPInter
URS00009B1CF7 RAB3GAP2 27087310 direct interaction,inhibition N/A NPInter

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