Gene Information gene info

  1. Home

GENE：SH3GLB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SH3GLB1
FullNmae SH3 domain containing GRB2 like, endophilin B1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10833
EnsembleID ENSG00000097033
Uniprot Q9Y371

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SH3GLB1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SH3GLB1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SH3GLB1 GO:0000139,GO:0000421,GO:0005515,GO:0005737,GO:0005741,GO:0005829,GO:0006914,GO:0006915,GO:0008289,GO:0010508,GO:0016020,GO:0016241,GO:0030496,GO:0031334,GO:0031410,GO:0031647,GO:0032465,GO:0032801,GO:0032991,GO:0034198,GO:0042149,GO:0042802,GO:0042803,GO:0045296,GO:0048102,GO:0061024,GO:0090148,GO:1903527,GO:1903778,GO:1903955,GO:2000786

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SH3GLB1 hsa:51100 path:hsa04140 Autophagy - animal - Homo sapiens (human)
SH3GLB1 hsa:51100 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BECN1 SH3GLB1 17891140 23180781 physical association anti tag coimmunoprecipitation InnateDB
UVRAG SH3GLB1 17891140 23180781 physical association anti tag coimmunoprecipitation InnateDB
GADD45A SH3GLB1 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP SH3GLB1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
SH3GLB1 CBL 11894095 20542890 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
E2F4 SH3GLB1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SH3GLB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SH3GLB1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SH3GLB1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SH3GLB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SH3GLB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SH3GLB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SH3GLB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SH3GLB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SH3GLB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SH3GLB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000272A3D SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000DDD35 SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000324096 SH3GLB1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000009262D SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 SH3GLB1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED SH3GLB1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 SH3GLB1 22100165 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B SH3GLB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000054D341 SH3GLB1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 SH3GLB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 SH3GLB1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB SH3GLB1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 SH3GLB1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SRC SH3GLB1 22135298 phosphorylation N/A PhosphoSite
SH3GLB1 BAX 25361965 interaction type N/A PTMCode2
BAX SH3GLB1 25361965 interaction type N/A PTMCode2
SH3GLB1 BIN1 25361965 interaction type N/A PTMCode2
BIN1 SH3GLB1 25361965 interaction type N/A PTMCode2
SH3GLB1 ATG5 25361965 interaction type N/A PTMCode2
ATG5 SH3GLB1 25361965 interaction type N/A PTMCode2
SH3GLB1 DNM2 25361965 interaction type N/A PTMCode2
DNM2 SH3GLB1 25361965 interaction type N/A PTMCode2
SH3GLB1 DNM1 25361965 interaction type N/A PTMCode2
DNM1 SH3GLB1 25361965 interaction type N/A PTMCode2
SH3GLB1 SH3KBP1 25361965 interaction type N/A PTMCode2
SH3KBP1 SH3GLB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I SH3GLB1 25348397 N/A physical interaction ComPPI
SH3GLB1 TPD52L2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 FUNDC1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 ZNF576 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 BAX 11161816 11259440 14525934 19074440 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SH3GLB1 AMPH 12456676 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SH3GLB1 BIN1 12456676 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SH3GLB1 ADAM9 10531379 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SH3GLB1 SYNJ1 14525934 14704270 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SH3GLB1 SH3GLB2 11161816 14525934 20562859 23414517 24234451 25348397 25416956 27107012 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid prey pooling approach,split luciferase complementation,validated two hybrid,barcode fusion genetics two hybrid,two hybrid ComPPI,HPRD,IntAct
SH3GLB1 MTA1 14525934 15978591 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SH3GLB1 ARHGAP17 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SH3GLB1 HTT 12456676 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SH3GLB1 USP7 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SH3GLB1 CUL2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SH3GLB1 KLHDC10 25348397 N/A physical interaction ComPPI
SH3GLB1 ITCH 25348397 N/A physical interaction ComPPI
SH3GLB1 ADAM15 16374509 24234451 25348397 physical association filter binding,physical interaction ComPPI,IntAct
SH3GLB1 APP 25348397 N/A physical interaction ComPPI
SH3GLB1 GADD45A 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SH3GLB1 GADD45G 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GLB1 AARSD1 25348397 N/A physical interaction ComPPI
SH3GLB1 ARPC1A 25348397 N/A physical interaction ComPPI
SH3GLB1 ARPC4 25348397 N/A physical interaction ComPPI
SH3GLB1 CALR 25348397 N/A physical interaction ComPPI
SH3GLB1 KIFBP 25348397 N/A physical interaction ComPPI
SH3GLB1 NSUN2 25348397 N/A physical interaction ComPPI
SH3GLB1 PRKACA 25348397 N/A physical interaction ComPPI
SH3GLB1 RANGAP1 25348397 N/A physical interaction ComPPI
SH3GLB1 ACTR2 25348397 N/A physical interaction ComPPI
SH3GLB1 ACTR3 25348397 N/A physical interaction ComPPI
SH3GLB1 AGFG1 25348397 N/A physical interaction ComPPI
SH3GLB1 ARPC2 25348397 N/A physical interaction ComPPI
SH3GLB1 CALU 25348397 N/A physical interaction ComPPI
SH3GLB1 HSPBP1 25348397 N/A physical interaction ComPPI
SH3GLB1 LAP3 25348397 N/A physical interaction ComPPI
SH3GLB1 P3H1 25348397 N/A physical interaction ComPPI
SH3GLB1 LPP 25348397 N/A physical interaction ComPPI
SH3GLB1 NIF3L1 25348397 N/A physical interaction ComPPI
SH3GLB1 RPA2 25348397 N/A physical interaction ComPPI
SH3GLB1 SH3GL1 25348397 N/A physical interaction ComPPI
SH3GLB1 THG1L 25348397 N/A physical interaction ComPPI
SH3GLB1 TPRKB 25348397 N/A physical interaction ComPPI
SH3GLB1 PSMA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 TFIP11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 CMTM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 SERPINB3 25348397 N/A physical interaction ComPPI
SH3GLB1 CCDC22 25348397 N/A physical interaction ComPPI
SH3GLB1 COMMD3 25348397 N/A physical interaction ComPPI
SH3GLB1 VPS26C 25348397 N/A physical interaction ComPPI
SH3GLB1 FLAD1 25348397 N/A physical interaction ComPPI
SH3GLB1 RPRD1A 25348397 N/A physical interaction ComPPI
SH3GLB1 USP14 25348397 N/A physical interaction ComPPI
SH3GLB1 WARS1 25348397 N/A physical interaction ComPPI
SH3GLB1 XPO7 25348397 N/A physical interaction ComPPI
SH3GLB1 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SH3GLB1 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SH3GLB1 HTATIP2 25348397 N/A physical interaction ComPPI
SH3GLB1 RAB5A 25348397 N/A physical interaction ComPPI
SH3GLB1 ACSL4 25348397 N/A physical interaction ComPPI
SH3GLB1 CDH1 25348397 N/A physical interaction ComPPI
SH3GLB1 FCGRT 25348397 N/A physical interaction ComPPI
SH3GLB1 SERPINB13 25348397 N/A physical interaction ComPPI
SH3GLB1 SCYL2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 PRCC 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 SEPTIN7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 DIS3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 CHORDC1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 SUB1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 COPZ1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 GORASP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 SEPTIN11 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 DRG1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 UVRAG 17891140 24056303 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SH3GLB1 PIK3C3 24056303 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SH3GLB1 ATG5 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 BECN1 20562859 24056303 24234451 25348397 association,physical association anti tag coimmunoprecipitation,molecular sieving ComPPI,IntAct
SH3GLB1 FLNC 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 KRI1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 ZNRD2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 ZNF207 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 LRRC59 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 TOE1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 WDR36 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 GYS1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 PGAM2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 RPL36AL 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 TMEM109 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 AGL 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 DDX27 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 TCOF1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 SQSTM1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 ITGB1BP2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 F8A1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 FN1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 GSTP1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 RABGGTB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 TAX1BP1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 TTN 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 UBL7 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 ARFIP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 DESI2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 SNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 COQ8A 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 RABAC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 MAL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 SYNGR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 SNX4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 CACFD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 SYP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 SMIM5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 RHEX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 FAM114A2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 ABHD5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GLB1 HSCB 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
SH3KBP1 SH3GLB1 25348397 N/A physical interaction ComPPI
PPP2R5D SH3GLB1 25348397 N/A physical interaction ComPPI
SARNP SH3GLB1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3GLB1 DNM2 12456676 14525934 16696976 N/A experimental interaction detection HPRD
SH3GLB1 SH3GLB1 11161816 14525934 20562859 23414517 24234451 25416956 association,physical association anti tag coimmunoprecipitation,two hybrid array,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid HPRD,IntAct
CDK5 SH3GLB1 21499257 27898060 N/A N/A OmniPath
SRC SH3GLB1 18474606 27898060 stimulant N/A OmniPath
SH3GLB1 BAK1 16227588 27898060 stimulant N/A OmniPath
SH3GLB1 CBL 11894095 27898060 stimulant N/A OmniPath
SH3GLB1 PIK3C3 17891140 27898060 stimulant N/A OmniPath
SH3GLB1 BECN1 17891140 21311563 27898060 stimulant N/A OmniPath
SH3GLB1 BAX 11161816 11259440 16227588 27898060 stimulant N/A OmniPath
UVRAG SH3GLB1 17891140 18032918 21068542 27898060 stimulant N/A OmniPath
SH3GLB1 UVRAG 17891140 18032918 21068542 27898060 stimulant N/A OmniPath

Visualization










  Return