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GENE：UBQLN4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBQLN4
FullNmae ubiquilin 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1237
EnsembleID ENSG00000160803
Uniprot Q9NRR5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBQLN4 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBQLN4 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
UBQLN4 GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005776,GO:0005789,GO:0005829,GO:0005829,GO:0005829,GO:0006281,GO:0006511,GO:0006914,GO:0006974,GO:0031410,GO:0031593,GO:0031593,GO:0031593,GO:0032434,GO:0032434,GO:0032991,GO:0036435,GO:0042802,GO:0048471,GO:0090734,GO:1901097,GO:2000042

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBQLN4 hsa:56893 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
UBQLN4 hsa:56893 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 UBQLN4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UBQLN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBQLN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 UBQLN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBQLN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBQLN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UBQLN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 UBQLN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE UBQLN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004E008F UBQLN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE UBQLN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD UBQLN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E UBQLN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000024A59E UBQLN4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032D69B UBQLN4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 UBQLN4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC UBQLN4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001067D1 UBQLN4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000156390 UBQLN4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D5391 UBQLN4 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
KLHL42 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
VPS4B UBQLN4 25348397 N/A physical interaction ComPPI
GPX7 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
RPN1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
SRGN UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
PPIB UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
PPIC UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
NME3 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
CD2BP2 UBQLN4 25348397 N/A physical interaction ComPPI
EFEMP2 UBQLN4 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IMPDH2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
HK2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
ATXN1 UBQLN4 11001934 14525934 16713569 24234451 25348397 27898060 colocalization,physical association two hybrid,physical interaction,fluorescence microscopy,two hybrid ComPPI,HPRD,IntAct,OmniPath
TRIM32 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
PNMA1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MOAP1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PICK1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UNC119 UBQLN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SMAD3 UBQLN4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CTSB UBQLN4 25348397 N/A physical interaction ComPPI
SPP1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
HGS UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SERPINH1 UBQLN4 11162551 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
UBC UBQLN4 25348397 N/A physical interaction ComPPI
LAT2 UBQLN4 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SMAD9 UBQLN4 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SERPINE1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
PRPF40A UBQLN4 14525934 15231748 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
COPB1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
BAG6 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
HSPA5 UBQLN4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRL UBQLN4 25348397 N/A physical interaction ComPPI
SEMG1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
TXN UBQLN4 25348397 N/A physical interaction ComPPI
EEF1A1 UBQLN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
STAM2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
GJB1 UBQLN4 25348397 N/A physical interaction ComPPI
PDLIM7 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
NPHP1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
MDK UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
GDI1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RBM10 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
YWHAQ UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMARCB1 UBQLN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TRAF2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RAD23A UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SRSF2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NAE1 UBQLN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MDM2 UBQLN4 14525934 17290220 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
TGFB1I1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FKBP2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
EDN1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 IGHM 16713569 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
UBQLN4 STMN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 MLLT6 14525934 16713569 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 NPPA 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 OAT 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 PTPRN 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 PTPRN2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 DMPK 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 PTN 14525934 16169070 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBQLN4 CCL21 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 AREG 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 FZD7 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 PIP4K2B 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 CRIPT 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 FGFBP1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 ARL4C 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 RNPS1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 ERP29 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 IMMT 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 CPSF6 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBQLN4 SCMH1 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBQLN4 TNRC6B 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 ZFPM2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 TRIB2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 UBQLN1 14525934 16713569 23459205 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
UBQLN4 KLHL26 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 DTX2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 PELI2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 MIF4GD 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 RIC8A 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 CCDC136 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBQLN4 RSRC2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 CCDC33 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 GKAP1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 ATP5MK 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 C1ORF94 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 ATP5IF1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 RNF11 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBQLN4 RUNX1T1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 CDSN 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 RXRA 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBQLN4 HERPUD1 25348397 N/A physical interaction ComPPI
UBQLN4 PSMD4 15280365 18079109 24256120 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBQLN4 GJA1 18079109 20940304 24256120 25348397 25583071 27898060 N/A physical interaction ComPPI,OmniPath
UBQLN4 DNAJB11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBQLN4 TNFRSF14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBQLN4 PSMD2 25348397 N/A physical interaction ComPPI
UBQLN4 NXF1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBQLN4 AHCYL1 25348397 N/A physical interaction ComPPI
UBQLN4 UBXN1 25348397 N/A physical interaction ComPPI
UBQLN4 UBE2A 25348397 N/A physical interaction ComPPI
UBQLN4 USP34 25348397 N/A physical interaction ComPPI
UBQLN4 TYMS 25348397 N/A physical interaction ComPPI
UBQLN4 STAM 25348397 N/A physical interaction ComPPI
UBQLN4 PRDX3 25348397 N/A physical interaction ComPPI
UBQLN4 UBE2C 25348397 N/A physical interaction ComPPI
UBQLN4 MAP1LC3A 23459205 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
UBQLN4 ORC5 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBQLN4 ASNS 25348397 N/A physical interaction ComPPI
UBQLN4 RAD23B 25348397 N/A physical interaction ComPPI
UBQLN4 KDELR1 25348397 N/A physical interaction ComPPI
UBQLN4 MTNR1B 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
UBQLN4 UBE2V1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
CSTF2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
TFF1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
SCG2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct

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