Gene Information gene info

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GENE：USP33

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP33
FullNmae ubiquitin specific peptidase 33
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20059
EnsembleID ENSG00000077254
Uniprot Q8TEY7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP33 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP33 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
USP33 GO:0001664,GO:0004197,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005654,GO:0005737,GO:0005794,GO:0005813,GO:0005829,GO:0005925,GO:0006511,GO:0006897,GO:0007411,GO:0008270,GO:0008277,GO:0009267,GO:0010506,GO:0016477,GO:0016579,GO:0016579,GO:0030891,GO:0031267,GO:0032091,GO:0032092,GO:0043025,GO:0048471,GO:0050821,GO:0051298,GO:0070536,GO:0071108

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 USP33 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 USP33 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 USP33 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USP33 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 USP33 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 USP33 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS USP33 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP33 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 USP33 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D USP33 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
GNAI3 USP33 25348397 N/A physical interaction ComPPI
USP20 USP33 25348397 N/A physical interaction ComPPI
TRAF6 USP33 25348397 N/A physical interaction ComPPI
VAPA USP33 25348397 N/A physical interaction ComPPI
UBC USP33 25348397 N/A physical interaction ComPPI
ITGB3BP USP33 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RALA USP33 25348397 N/A physical interaction ComPPI
EIF6 USP33 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
APBA2 USP33 25348397 N/A physical interaction ComPPI
EXOC2 USP33 25348397 N/A physical interaction ComPPI
RALB USP33 25348397 N/A physical interaction ComPPI
ARRB1 USP33 25348397 N/A physical interaction ComPPI
ARRB2 USP33 19363159 19424180 24377933 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ADRB2 USP33 19424180 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
VAPB USP33 25348397 N/A physical interaction ComPPI
VHL USP33 11739384 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TRIM63 USP33 25348397 N/A physical interaction ComPPI
TLR2 USP33 25348397 N/A physical interaction ComPPI
ELOB USP33 25348397 N/A physical interaction ComPPI
ELOC USP33 11739384 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
USP33 DDX56 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
USP33 KRR1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP33 IFIT5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP33 ZFR 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP33 ROBO1 19684588 19706539 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
USP33 ELAVL1 25348397 N/A physical interaction ComPPI
USP33 TRIM54 25348397 N/A physical interaction ComPPI
USP33 USP21 25348397 N/A physical interaction ComPPI
USP33 USP15 25348397 N/A physical interaction ComPPI
USP33 USP28 25348397 N/A physical interaction ComPPI
USP33 CCP110 25348397 N/A physical interaction ComPPI
USP33 BECN1 25348397 N/A physical interaction ComPPI
USP33 PCGF6 25348397 N/A physical interaction ComPPI
CHRM5 USP33 24234451 28298427 physical association ubiquitin reconstruction IntAct

Source Target Pmid Interactiontype Methods Database
URS00008B60D5 USP33 27087310 direct interaction,inhibition N/A NPInter
URS00009B0E59 USP33 27087310 direct interaction,inhibition N/A NPInter

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