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GENE：NEK7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NEK7
FullNmae NIMA related kinase 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13386
EnsembleID ENSG00000151414
Uniprot Q8TDX7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NEK7 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NEK7 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NEK7 GO:0000922,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005815,GO:0005874,GO:0006468,GO:0007346,GO:0007346,GO:0018105,GO:0032212,GO:0035865,GO:0046872,GO:0051225,GO:0051973,GO:0051973,GO:0106310,GO:0140677,GO:1900227,GO:1904355

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NEK7 hsa:140609 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NSD2 NEK7 23180781 25280969 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NEK7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NEK7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NEK7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NEK7 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 NEK7 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NEK7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA NEK7 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00004AC389 NEK7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 NEK7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075994C NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 NEK7 22100165 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 NEK7 22100165 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 NEK7 22100165 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F NEK7 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 NEK7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E NEK7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 NEK7 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NEK9 NEK7 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
DYNLL1 NEK7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CBSL NEK7 25348397 N/A physical interaction ComPPI
NFATC1 NEK7 25348397 N/A physical interaction ComPPI
P4HB NEK7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 NEK7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TNF NEK7 25348397 N/A physical interaction ComPPI
PTPN21 NEK7 25348397 N/A physical interaction ComPPI
TRIM25 NEK7 25348397 N/A physical interaction ComPPI
TERF1 NEK7 25348397 N/A physical interaction ComPPI
NEK9 NEK7 12840024 14525934 20562859 24234451 25348397 27173435 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
RREB1 NEK7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NEK6 NEK7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NLRP3 NEK7 24234451 25348397 26814970 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NEK7 LAMP3 25348397 N/A physical interaction ComPPI
NEK7 ZNF669 25348397 N/A physical interaction ComPPI
NEK7 ZNF214 25348397 N/A physical interaction ComPPI
NEK7 PCDHGB1 25348397 N/A physical interaction ComPPI
NEK7 IL13RA2 25348397 N/A physical interaction ComPPI
NEK7 P4HA2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NEK7 SLC39A9 25348397 N/A physical interaction ComPPI
NEK7 ZNF331 25348397 N/A physical interaction ComPPI
NEK7 DPH3 25348397 N/A physical interaction ComPPI
NEK7 LLGL2 25348397 N/A physical interaction ComPPI
NEK7 GPR107 25348397 N/A physical interaction ComPPI
NEK7 ZNF556 25348397 N/A physical interaction ComPPI
NEK7 ANKS3 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NEK7 ANKS6 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NEK7 SCYL1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NEK7 EML4 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NEK7 CBS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NEK7 WDR19 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NEK7 IFT122 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NEK7 WDR35 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NEK8 NEK7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
NEK9 NEK7 12840024 18452278 18691976 19369195 20562859 27898060 stimulant N/A OmniPath

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